scholarly journals Randomized Comparison of the Nobori Biolimus A9-Eluting Coronary Stent With the Taxus Liberté Paclitaxel-Eluting Coronary Stent in Patients With Stenosis in Native Coronary Arteries

2009 ◽  
Vol 2 (3) ◽  
pp. 188-195 ◽  
Author(s):  
Bernard Chevalier ◽  
Sigmund Silber ◽  
Seung-Jung Park ◽  
Eulogio Garcia ◽  
Gerhard Schuler ◽  
...  
2018 ◽  
Vol 33 (1) ◽  
pp. 64-71 ◽  
Author(s):  
Jinpeng Wang ◽  
Chunli Song ◽  
Yanlong Xiao ◽  
Bin Liu

Currently, percutaneous coronary intervention is an important treatment for coronary heart disease. However, the in-stent restenosis rate is still approximately 10–30% after stenting. Nickel ions from the stent are considered to be associated with in-stent restenosis. Therefore, in the present study, we quantitatively evaluated in-stent restenosis after implanting the novel high-nitrogen low-nickel coronary stent (HNS) and studied the mechanism underlying the reduction in in-stent restenosis by using ELISA and Western blot. The in vivo results showed that the HNS could significantly reduce neointima formation and inflammation as compared to SUS316L stents (316L) at 180 days after implantation in porcine coronary arteries and that vascular endothelial growth factor-A expression in porcine coronary arteries after HNS implantation also decreased. The in vitro results showed that, in the case of the HNS, human umbilical vein endothelial cell (HUVEC) proliferation was lower and lesser IL-6 release was noted from HUVECs at one and three days after culture than in the 316L group. Furthermore, p-STAT3 expression in HUVECs on the HNS surface was downregulated after culture for seven days. Thus, we conclude that the HNS could be a promising alternative coronary stent for percutaneous coronary intervention.


Circulation ◽  
2002 ◽  
Vol 105 (25) ◽  
pp. 2986-2991 ◽  
Author(s):  
Takeshi Kimura ◽  
Kenichi Abe ◽  
Satoshi Shizuta ◽  
Keita Odashiro ◽  
Yoshinori Yoshida ◽  
...  

2010 ◽  
Vol 55 (10) ◽  
pp. A194.E1811
Author(s):  
Hitomi Hagiwara ◽  
Masashige Sasaki ◽  
Yoshiaki Hiraishi ◽  
Hisako Terao ◽  
Junji Kimura ◽  
...  

2002 ◽  
Vol 40 (5) ◽  
pp. 882-889 ◽  
Author(s):  
Jörg Hausleiter ◽  
Adnan Kastrati ◽  
Julinda Mehilli ◽  
Helmut Schühlen ◽  
Jürgen Pache ◽  
...  

2015 ◽  
Vol 86 (7) ◽  
pp. 1151-1160 ◽  
Author(s):  
Philip Urban ◽  
Mariano Valdés ◽  
Ian Menown ◽  
Franz Eberli ◽  
Imad Alhaddad ◽  
...  

2012 ◽  
Vol 80 (4) ◽  
pp. 546-553 ◽  
Author(s):  
Louis A. Cannon ◽  
Daniel I. Simon ◽  
Dean Kereiakes ◽  
Jennifer Jones ◽  
Roxana Mehran ◽  
...  

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