scholarly journals Impact of Mitral Valve Regurgitation Evaluated by Intraoperative Transesophageal Echocardiography on Long-Term Outcomes After Coronary Artery Bypass Grafting

Circulation ◽  
2005 ◽  
Vol 112 (9_supplement) ◽  
Author(s):  
Jacob N. Schroder ◽  
Matthew L. Williams ◽  
Jonathan A. Hata ◽  
Lawrence H. Muhlbaier ◽  
Madhav Swaminathan ◽  
...  
Keyword(s):  
Heart Failure ◽  
Mitral Valve ◽  
Artery Bypass ◽  
Mitral Valve Regurgitation ◽  
Valve Regurgitation ◽  
Heart Failure Hospitalization ◽  
Intraoperative Transesophageal Echocardiography ◽  
Cabg Patients

Background— It is unclear if mild or moderate mitral valve regurgitation (MR) should be repaired at the time of coronary artery bypass grafting (CABG). We sought to determine the long-term effect of uncorrected MR, measured by intraoperative transesophageal echocardiography (TEE), in CABG patients. Methods and Results— Between May 1999 and September 2003, data were gathered for 3264 consecutive patients who underwent isolated CABG and had MR graded by intraoperative TEE. MR was graded on the following 5 levels: none, trace, mild, moderate, and severe. Patients who had severe MR or who underwent mitral valve surgery were eliminated from the analysis. The remaining patients were combined into the following 3 groups: none or trace, mild, and moderate MR. Preoperative and follow-up data were 99% complete. The median length of follow-up was 3.0 years. Multivariable analysis controlling for important preoperative risk factors was performed to determine predictors of death and death/hospitalization for heart failure. Increasing MR was a risk factor for death [hazard ratio (HR), 1.44; P <0.001] and death/heart failure hospitalization (HR, 1.34; P <0.01). When patients with moderate MR were eliminated from the analysis, mild MR was a risk factor for death (HR, 1.34; P =0.011) and death/hospitalization for heart failure (HR, 1.34; P <0.001). Conclusions— Even mild MR, identified by intraoperative TEE, predicts worse outcomes after CABG. Revascularization alone did not eliminate the negative long-term effects of mild MR. CABG patients with uncorrected mild or moderate MR are at increased risk for death and heart-failure hospitalization; consideration for surgical repair or more aggressive medical management and follow-up is warranted.

A Simplified Technique for Correcting Mitral Valve Regurgitation via Minimally Invasive Approach

2018 ◽  
Vol 13 (3) ◽  
pp. 236-238
Author(s):  
Giuseppe Speziale ◽  
Marco Moscarelli
Keyword(s):  
Cardiopulmonary Bypass ◽  
Mitral Valve ◽  
Mitral Regurgitation ◽  
Minimally Invasive ◽  
Mitral Valve Regurgitation ◽  
Valve Regurgitation ◽  
Minimally Invasive Approach ◽  
Invasive Approach ◽  
Repair Techniques

Mitral valve regurgitation may require complex repair techniques that are challenging in minimally invasive and may expose patients to prolonged cardiopulmonary bypass and cross-clamp times. Here, we present a stepwise operative approach that may facilitate the repair of the mitral valve in a minimally invasive fashion and may be carried out even when multiple posterior segments are involved. This how-to-do article presents a method that was performed in 148 patients that were referred to our institution for severe organic mitral regurgitation between 2008 and 2016. At mean ± SD follow-up of 45.5 ± 27 months, freedom from recurrent of mitral regurgitation 2+ or greater and reoperation was 95.2%.

Previous malignancy is an independent predictor of follow-up mortality after percutaneous treatment of mitral valve regurgitation by means of MitraClip

2017 ◽  
Vol 35 (2) ◽  
pp. e12239 ◽  
Author(s):  
Alper Öner ◽  
Hüseyin Ince ◽  
Liliya Paranskaya ◽  
Guido Schröder ◽  
Mohammad Sherif ◽  
...  
Keyword(s):  
Mitral Valve ◽  
Independent Predictor ◽  
Percutaneous Treatment ◽  
Mitral Valve Regurgitation ◽  
Valve Regurgitation

scholarly journals TCT-825 In-Vivo Long Term Evaluation of a Novel Mitral Valve Regurgitation Therapy: Experience in a Preclinical Large Animal Model

2013 ◽  
Vol 62 (18) ◽  
pp. B249
Author(s):  
Athanasios Peppas ◽  
Jon Wilson ◽  
Yanping Cheng ◽  
Christopher Seguin ◽  
Masahiko Shibuya ◽  
...  
Keyword(s):  
Animal Model ◽  
Mitral Valve ◽  
Mitral Valve Regurgitation ◽  
Large Animal Model ◽  
Large Animal ◽  
Valve Regurgitation ◽  
Term Evaluation

scholarly journals Mitral regurgitation in Dachshund dogs without heart murmurs

2017 ◽  
Vol 61 (3) ◽  
pp. 363-366
Author(s):  
Magdalena Garncarz ◽  
Marta Parzeniecka-Jaworska ◽  
Magdalena Hulanicka ◽  
Michał Jank ◽  
Olga Szaluś-Jordanow ◽  
...  
Keyword(s):  
Heart Failure ◽  
Mitral Valve ◽  
Mitral Regurgitation ◽  
Mitral Valve Prolapse ◽  
Mitral Valve Disease ◽  
Mitral Valve Regurgitation ◽  
Valve Disease ◽  
Valve Regurgitation ◽  
Heart Murmurs ◽  
Few Data

Abstract Introduction: Older small breed dogs are considered at risk for heart failure secondary to chronic mitral valve disease. However, few data are available on the onset of this disease in such dogs. This study was performed to determine if auscultation alone can be used to eliminate clinically relevant mitral valve regurgitation seen in echocardiography in Dachshund dogs. Material and Methods: Clinical and echocardiographic data were obtained from 107 dogs without heart murmurs. Results: The study revealed that 63.6% of the dogs had mitral regurgitation. Numbers increased with age and a larger percentage of male Dachshunds were affected than female Dachshunds. Mitral valve prolapse and thickening were mild, and the regurgitant area inextensive in most dogs. Conclusions: The study shows that mitral valve regurgitation is prevalent (63.6%) in Dachshunds without heart murmurs. Typical lesions often become apparent during echocardiographic examinations in dogs under 5 years of age.

Percutaneous repair of mitral valve regurgitation in patients with severe heart failure: comparison with optimal medical treatment

2017 ◽  
Vol 73 (4) ◽  
pp. 378-386 ◽  
Author(s):  
Nicolas Geis ◽  
Philip Raake ◽  
Markus Lewening ◽  
Derliz Mereles ◽  
Emmanuel Chorianopoulos ◽  
...  
Keyword(s):  
Heart Failure ◽  
Mitral Valve ◽  
Medical Treatment ◽  
Severe Heart Failure ◽  
Mitral Valve Regurgitation ◽  
Valve Regurgitation ◽  
Percutaneous Repair

scholarly journals CRT and exercise capacity in heart failure: the impact of mitral valve regurgitation

EP Europace ◽  
2008 ◽  
Vol 10 (Supplement 3) ◽  
pp. iii96-iii100 ◽  
Author(s):  
F. I. Parthenakis ◽  
A. P. Patrianakos ◽  
E. N. Simantirakis ◽  
P. E. Vardas
Keyword(s):  
Heart Failure ◽  
Mitral Valve ◽  
Exercise Capacity ◽  
Mitral Valve Regurgitation ◽  
Valve Regurgitation ◽  
The Impact

Long-term results of mitral valvuloplasty for mitral valve regurgitation due to rheumatic valvulitis

1995 ◽  
Vol 3 ◽  
pp. 98-98
Author(s):  
K TANO ◽  
K EISHI ◽  
J KOBAYASHI ◽  
Y SASAKO ◽  
S NAKANO ◽  
...  
Keyword(s):  
Mitral Valve ◽  
Mitral Valve Regurgitation ◽  
Long Term Results ◽  
Valve Regurgitation ◽  
Mitral Valvuloplasty

scholarly journals Clinical and Angiographic Outcomes in Coronary Artery Bypass Surgery with Multiple versus Single Distal Target Grafts

2017 ◽  
Vol 20 (4) ◽  
pp. 132
Author(s):  
Aws Alherbish ◽  
Colleen M Norris ◽  
Jay Shavadia ◽  
Mohammad Almutawa ◽  
Seraj Abualnaja ◽  
...  
Keyword(s):  
Coronary Artery ◽  
Coronary Artery Bypass ◽  
Graft Failure ◽  
Artery Bypass ◽  
Population Based ◽  
Complete Revascularization ◽  
Graft Material ◽  
Cabg Patients

Background: Coronary artery bypass grafting (CABG) with multiple distal target (MDT) grafts requires less graft material and reduces cardiopulmonary bypass time; however, there may be a higher incidence of graft failure. A real-world analysis reporting long-term outcomes associated with MDT grafts is lacking.Material and Methods: In 6262 consecutive patients who underwent an isolated first CABG from 2004-2012, patients with MDTs were propensity matched to those with single distal target (SDT) grafts. Logistic regression adjusted for traditional, anatomical, and functional definitions of complete revascularization (CR). Outcomes included 30-day, 1-year, and long-term mortality (median 6.29 years). Results: A total of 549 (8.8%) CABG patients had a MDT graft. CR defined using traditional (96.1% versus 92.0%, P = .005), anatomical (89.0% versus 80.20%, P < .001), and functional (90.7% versus 82.6, P < .001) definitions was more frequent in MDT patients. No significant differences in mortality were observed at 30 days (2% versus 3.3%, P = .18), 1-year (3.8% versus 4.9%, P = .37), or through end of follow-up (18.0% versus 16.6% P = .52) between the MDT and SDT groups, respectively. Similarly, no differences were observed after adjustment for all definitions of CR. Graft failure in MDT and SDT patients was 37.8% and 27.6%, respectively (P = .18).Conclusion: In a contemporary population-based cohort, no differences in mortality were observed between CABG patients with MDT and SDT grafts. Our findings support the safety of MDT grafts to facilitate CR in patients and when graft material is limited.

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