Tigecycline In Vitro Activity Against Vancomycin-Resistant Enterococci And Methicillin-Resistant Staphylococcus Aureus In Critical Care Units

2012 ◽  
Author(s):  
Martha Renteria ◽  
Sam Bouchillon ◽  
Brian Johnson ◽  
Daryl Hoban ◽  
Mike Dowzicky
Keyword(s):  
Staphylococcus Aureus ◽  
Critical Care ◽  
Methicillin Resistant Staphylococcus Aureus ◽  
Vitro Activity ◽  
In Vitro Activity ◽  
Methicillin Resistant ◽  
Critical Care Units ◽  
Vancomycin Resistant Enterococci ◽  
Vancomycin Resistant

scholarly journals In vitro activity of LY333328, an investigational glycopeptide antibiotic, against enterococci and staphylococci.

1996 ◽  
Vol 40 (10) ◽  
pp. 2416-2419 ◽  
Author(s):  
R S Schwalbe ◽  
A C McIntosh ◽  
S Qaiyumi ◽  
J A Johnson ◽  
R J Johnson ◽  
...  
Keyword(s):  
Staphylococcus Aureus ◽  
Methicillin Resistant Staphylococcus Aureus ◽  
Vitro Activity ◽  
In Vitro Activity ◽  
Glycopeptide Antibiotic ◽  
Methicillin Resistant ◽  
Vancomycin Resistant Enterococci ◽  
Vancomycin Resistant

The in vitro activities of LY333328 were compared with those of vancomycin, teicoplanin, and quinupristin-dalfopristin (Synercid) against 219 strains of enterococci and staphylococci, including vancomycin-resistant enterococci and methicillin-resistant Staphylococcus aureus. MICs and MBCs were determined by a microtiter dilution protocol. LY333328 demonstrated superior activity against vancomycin-resistant enterococci and was the only antibiotic which was bactericidal. Its potency was comparable or superior to those of other antibiotics tested against methicillin-resistant staphylococci.

scholarly journals In vitro activity of minocycline combined with fosfomycin against clinical isolates of methicillin-resistant Staphylococcus aureus

2011 ◽  
Vol 64 (8) ◽  
pp. 559-562 ◽  
Author(s):  
Chunguang Sun ◽  
Matthew E Falagas ◽  
Rui Wang ◽  
Drosos E Karageorgopoulos ◽  
Xuhong Yu ◽  
...  
Keyword(s):  
Staphylococcus Aureus ◽  
Methicillin Resistant Staphylococcus Aureus ◽  
Vitro Activity ◽  
Clinical Isolates ◽  
In Vitro Activity ◽  
Methicillin Resistant

scholarly journals In Vitro Activity and Killing Effect of Uperin 3.6 against Gram-Positive Cocci Isolated from Immunocompromised Patients

2005 ◽  
Vol 49 (9) ◽  
pp. 3933-3936 ◽  
Author(s):  
Andrea Giacometti ◽  
Oscar Cirioni ◽  
Wojciech Kamysz ◽  
Carmela Silvestri ◽  
Alberto Licci ◽  
...  
Keyword(s):  
Vitro Activity ◽  
Immunocompromised Patients ◽  
In Vitro Activity ◽  
Gram Positive ◽  
Killing Effect ◽  
Methicillin Resistant ◽  
Vancomycin Resistant Enterococci ◽  
Vancomycin Resistant ◽  
Gram Positive Cocci

ABSTRACT The in vitro activity of uperin 3.6, alone or combined with six antibiotics, against gram-positive cocci, including Rhodococcus equi, methicillin-resistant staphylococci, and vancomycin-resistant enterococci, was investigated. All isolates were inhibited at concentrations of 1 to 16 mg/liter. Synergy was demonstrated when uperin 3.6 was combined with clarithromycin and doxycycline.

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