Antimicrobial Prophylaxis for Recurrent Acute Otitis Media

1981 ◽  
Vol 90 (3_suppl2) ◽  
pp. 53-57 ◽  
Author(s):  
Jack L. Paradise
Keyword(s):  
Otitis Media ◽  
Antimicrobial Prophylaxis ◽  
Acute Otitis Media ◽  
Management Option ◽  
Recurrent Acute Otitis Media

Antimicrobial prophylaxis for children who have frequently recurring, severe episodes of acute otitis media appears to constitute a reasonable management option, even though it is not yet clear whether the advantages outweigh the disadvantages and risks. It remains for well-designed and well-executed studies that extend over relatively long periods to indicate whether this approach to management is the best of the available options, and if so, which of the available drugs is preferable.

Preventing Otitis Media

1994 ◽  
Vol 103 (5_suppl) ◽  
pp. 20-23 ◽  
Author(s):  
G. Scott Giebink
Keyword(s):  
Otitis Media ◽  
Otitis Media With Effusion ◽  
Antimicrobial Prophylaxis ◽  
Acute Otitis Media ◽  
Tympanostomy Tube ◽  
Tube Insertion ◽  
Protein Conjugate ◽  
Recurrent Acute Otitis Media ◽  
Prevalent Disease ◽  
The Common

Recurrent acute otitis media (AOM) is an extremely prevalent disease in young children. Epidemiologic associations suggest that primary prevention or reduction of AOM frequency may be achieved with breast-feeding during infancy, elimination of household tobacco smoking, and use of small rather than large day-care arrangements for infants and toddlers. Secondary antimicrobial prophylaxis with amoxicillin or sulfisoxazole reduces the frequency of recurrent AOM by about 50%, but it does not appear to reduce the duration of otitis media with effusion (OME). Tympanostomy tube insertion is not as effective as amoxicillin in reducing AOM frequency in children without OME. Adenoidectomy appears to be warranted for children who develop recurrent AOM after extrusion of tubes. Vaccines against the common bacteria and viruses causing AOM hold the greatest promise of preventing AOM and blocking the sequence of pathologic events leading to chronic OME and middle ear sequelae. The greatest progress has been made recently with pneumococcal protein conjugate vaccines, and clinical testing is in progress.

Efficacy of antimicrobial prophylaxis and of tympanostomy tube insertion for prevention of recurrent acute otitis media

1992 ◽  
Vol 11 (4) ◽  
pp. 278-285 ◽  
Author(s):  
MARGARETHA L. CASSELBRANT ◽  
PHILLIP H. KALEIDA ◽  
HOWARD E. ROCKETTE ◽  
JACK L. PARADISE ◽  
CHARLES D. BLUESTONE ◽  
...  
Keyword(s):  
Otitis Media ◽  
Antimicrobial Prophylaxis ◽  
Acute Otitis Media ◽  
Tympanostomy Tube ◽  
Tube Insertion ◽  
Recurrent Acute Otitis Media

Antimicrobial Prophylaxis

1994 ◽  
Vol 15 (10) ◽  
pp. 377-382
Author(s):  
Gordon E. Schutze ◽  
Richard F. Jacobs
Keyword(s):  
Otitis Media ◽  
Otitis Media With Effusion ◽  
Antimicrobial Prophylaxis ◽  
Acute Otitis Media ◽  
Tube Placement ◽  
Common Diagnosis ◽  
Recurrent Acute Otitis Media ◽  
Immunosuppressed Patients ◽  
Potential Benefits ◽  
Micro Organisms

The issue of antimicrobial prophylaxis in preventing infections in infants and children is important in the practice of pediatrics. Children are especially prone to certain infections, and pathogens are amenable to prophylaxis. Chemoprophylaxis may be used to prevent primary disease (eg, ophthalmia neonatorum) or recurrent infections (eg, otitis media). Individuals exposed to certain micro-organisms (eg, Neisseria meningitidis) or immunosuppressed patients (eg, those who are asplenic) may benefit from prophylaxis in certain situations. The duration of chemoprophylaxis may be as short as two doses (eg, endocarditis prophylaxis) or may last a lifetime (eg, rheumatic fever prophylaxis). Questions concerning the potential benefits of antimicrobial prophylaxis are quite common, and many of the answers are controversial. Because the list of specific pathogens and conditions for prophylaxis is quite long, this review will encompass only the more common conditions encountered in a busy general pediatric practice (Table 1). Otitis Media Acute otitis media is the most common diagnosis made in children when visits to the physician are prompted by illness. For every three children who have acute otitis media with effusion, one will suffer from recurrent acute otitis media: antimicrobial prophylaxis, tympanostomy tube placement, and adenoidectomy. Of these options, only chemoprophylaxis can be managed by the primary physician.

Antimicrobial prophylaxis for infants at risk for recurrent acute otitis media

Vaccine ◽  
2000 ◽  
Vol 19 ◽  
pp. S140-S143 ◽  
Author(s):  
David W Teele ◽  
Jerome O Klein ◽  
Bonnie M Word ◽  
Bernard A Rosner ◽  
Sidney Starobin ◽  
...  
Keyword(s):  
At Risk ◽  
Otitis Media ◽  
Antimicrobial Prophylaxis ◽  
Acute Otitis Media ◽  
Recurrent Acute Otitis Media

Recurrent Acute Otitis Media: The Significance of Age at Onset

1997 ◽  
Vol 117 (4) ◽  
pp. 578-584 ◽  
Author(s):  
Kari J. Kværner ◽  
Per Nafstad ◽  
Jørgen A. Hagen ◽  
Iain W. S. Mair ◽  
Jouni J. K. Jaakkola
Keyword(s):  
Otitis Media ◽  
Age At Onset ◽  
Acute Otitis Media ◽  
Recurrent Acute Otitis Media
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