Combination of Calcium Channel Blockers and Beta-Blockers for Patients with Exercise-Induced Angina Pectoris: Beneficial Effect of Calcium Channel Blockers Largely Determined by Their Effect on Heart Rate

1999 ◽  
Vol 39 (7) ◽  
pp. 738-746 ◽  
Author(s):  
Ton J. Cleophas ◽  
Johan van der Sluijs ◽  
Jan A. van der Vring ◽  
Marcel C. Daniëls ◽  
Klaas J. Holwerda ◽  
...  
Keyword(s):  
Heart Rate ◽  
Angina Pectoris ◽  
Beneficial Effect ◽  
Calcium Channel ◽  
Calcium Channel Blockers ◽  
Beta Blockers ◽  
Channel Blockers ◽  
Exercise Induced

scholarly journals Sequential comparison of therapy with beta-blockers and calcium channel blockers with celiprolol therapy in patients with angina pectoris, hypertension, or both

1996 ◽  
Vol 57 (8) ◽  
pp. 614-621
Author(s):  
Ton J.M. Cleophas ◽  
Menlo G. Niemeyer ◽  
Piet J.L.M. Bernink ◽  
Koos H. Zwinderman ◽  
Anton V. Wijk ◽  
...  
Keyword(s):  
Angina Pectoris ◽  
Calcium Channel ◽  
Calcium Channel Blockers ◽  
Beta Blockers ◽  
Channel Blockers ◽  
Sequential Comparison

Cardiotoxicity with antihypertensive drugs (literature review) Part 1. Calcium channel blockers and beta-blockers

2021 ◽  
pp. 12-19
Author(s):  
A. N. Esaulenko ◽  
A. Yu. Moiseeva ◽  
A. A. Ivannikov ◽  
I. V. Bratischev ◽  
Kh. G. Alidzhanova
Keyword(s):  
Calcium Channel ◽  
Calcium Channel Blockers ◽  
Antihypertensive Drugs ◽  
Beta Blockers ◽  
Research Literature ◽  
Channel Blockers ◽  
Distinctive Features ◽  
Experimental Pharmacology ◽  
Myocardial Insufficiency ◽  
Β Blockers

The effect of hypotensive drugs overdose on cardiovascular system is poorly studied; it should undergo clinical, experimental pharmacology and toxicology together with cardiology. There is too little information about cardiotoxicity of beta-blockers (β-blockers) and calcium channel blockers (CCB) in existing research literature. Intoxication from these groups of drugs causes similar severe hemodynamic abnormalities and myocardial insufficiency, however pathophysiological mechanisms of these abnormalities are not thoroughly studied. The review highlights how difficult it is to identify toxic level and distinctive features of clinical evidence of intoxication. Methods of diagnosis as well as β-blockers and CCB overdose treatment are discussed.

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