scholarly journals Corrigendum

2018 ◽  
Vol 159 (2) ◽  
pp. 402-402

Vila PM, Zenga J, Fowler S, Jackson RS. Antibiotic prophylaxis in clean-contaminated head and neck surgery: a systematic review and meta-analysis. Otolaryngol Head Neck Surg. 2017;157:580-588. (Original DOI: 10.1177/0194599817712215) This article was printed in the October 2017 issue with the third author, Susan Fowler, omitted. The online version of this article has been corrected to accurately reflect Susan Fowler’s authorship: Susan Fowler’s name was added as the third author in the byline and her affiliation was added to the footnotes (Washington University in St Louis, St Louis, Missouri, USA). Her contributions have also been added to the Author Contributions section.

2020 ◽  
Vol 37 (4) ◽  
pp. 1360-1380 ◽  
Author(s):  
Vincent Vander Poorten ◽  
Saartje Uyttebroek ◽  
K. Thomas Robbins ◽  
Juan P. Rodrigo ◽  
Remco de Bree ◽  
...  

2017 ◽  
Vol 157 (4) ◽  
pp. 580-588 ◽  
Author(s):  
Peter M. Vila ◽  
Joseph Zenga ◽  
Susan Fowler ◽  
Ryan S. Jackson

Objective To determine the optimal duration and type of antibiotic prophylaxis in patients undergoing clean-contaminated resection for head and neck cancer. Data Sources Search strategies were created by a medical librarian, implemented in multiple databases, and completed in June 2016. Review Methods The population of interest was adults ≥18 years undergoing clean-contaminated head and neck surgery, intervention was postoperative antibiotic prophylaxis, comparator was duration and types of antibiotics used, outcome was the wound infection rate, and the study design was randomized controlled trials (RCTs). Studies were excluded if not randomized, did not use systemic antibiotics, did not study wound infections, or included children. After excluding duplicates, the search strategy yielded 427 abstracts. After applying inclusion and exclusion criteria, 67 studies were screened, leaving 19 RCTs for review. PRISMA guidelines were followed. A random-effects model was used for meta-analysis. Results Meta-analysis of 340 patients in 4 RCTs showed that the pooled relative risk of wound infection was 0.98 (95% confidence interval [CI], 0.58-1.61; P = .718; I2 = 0.0%) in patients receiving 1 day vs 5 days of prophylaxis. Conclusion This study provides evidence that there is no difference in the risk of wound infection with 1 day vs 5 days of systemic antibiotic prophylaxis in clean-contaminated head and neck surgery, consistent with existing guidelines. Future large randomized trials are needed to more clearly define the appropriate choice of prophylaxis in penicillin-allergic patients.


1992 ◽  
Vol 101 (1_suppl) ◽  
pp. 16-20 ◽  
Author(s):  
Randal S. Weber ◽  
David L. Callender

The use of antibiotic prophylaxis in head and neck oncologic surgery has greatly reduced the risk of postoperative wound infection and the corresponding increase in morbidity and health care costs. Conversely, inappropriate perioperative use of antibiotics increases costs and risks to patients. Antibiotic prophylaxis is beneficial only in clean-contaminated head and neck surgery; targets are the bacterial flora that commonly inhabit the skin and upper aerodigestive tract, with antibiotics effective against gram-positive aerobic organisms and anaerobic organisms providing the best coverage. Maximum efficacy is achieved with immediate preoperative and short-term (< 48 hours) postoperative antimicrobial administration in adequate doses. Optimum benefit from prophylaxis in head and neck oncologic surgery depends on appropriate selection and administration of antibiotics in combination with sound, established surgical principles.


Head & Neck ◽  
2017 ◽  
Vol 39 (6) ◽  
pp. 1249-1258 ◽  
Author(s):  
Sami P. Moubayed ◽  
Antoine Eskander ◽  
Moustafa W. Mourad ◽  
Sam P. Most

Head & Neck ◽  
2019 ◽  
Vol 41 (9) ◽  
pp. 3434-3456 ◽  
Author(s):  
Carlos Miguel Chiesa‐Estomba ◽  
Jérome R. Lechien ◽  
Nicolas Fakhry ◽  
Antoine Melkane ◽  
Christian Calvo‐Henriquez ◽  
...  

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