Mid-Term Experience with Valved Bovine Jugular Vein Conduits

2005 ◽  
Vol 13 (4) ◽  
pp. 361-365 ◽  
Author(s):  
Malgorzata Pawelec-Wojtalik ◽  
Wojciech Mrówczyński ◽  
Andrzej Wodziński ◽  
Michal Wojtalik ◽  
Jacek Henschke ◽  
...  
Keyword(s):  
Balloon Dilatation ◽  
Jugular Vein ◽  
Heart Defects ◽  
Sudden Cardiac Arrest ◽  
Right Ventricular Outflow Tract ◽  
Ventricular Outflow Tract ◽  
Good Alternative ◽  
Percutaneous Balloon ◽  
Bovine Jugular Vein

From June 1999 to January 2004, 43 children underwent implantation of a valved bovine jugular vein conduit and correction of complex congenital heart defects. Median age was 1.98 years (range, 11 days – 13.3 years). There were 7 early deaths (16.3%) unrelated to conduit failure or thrombosis. Median follow-up of 36 survivors was 24 months (range, 1–48 months, quartile range, 12–48 months), total follow-up was 78 patient-years. There were 3 late deaths (8.3%) due to infection, pulmonary thromboembolism, and sudden cardiac arrest after re-operation to repair a right ventricular outflow tract aneurysm. There were 2 conduit explantations due to dysfunction and suspected endocarditis. Three patients underwent balloon dilatation of distal stenoses. The mean peak gradient through the pulmonary anastomosis was 15 mm Hg (range, 3–42 mm Hg) among patients free from re-intervention. No severe valve regurgitation was observed. Freedom from re-intervention was 72% at 48 months. This conduit remains a good alternative to homografts. Causes of distal stenosis must be clarified, guidelines for prophylactic anticoagulation must be created, and the role of percutaneous balloon dilatation established.

scholarly journals Midterm Outcomes of Crosslinked Acellular Bovine Jugular Vein Conduit for Right Ventricular Outflow Tract Reconstruction

2021 ◽  
Vol 9 ◽  
Author(s):  
Tao Qian ◽  
Zhong-Shi Wu ◽  
Jian-Guo Hu ◽  
Yi-Feng Yang ◽  
Qin Wu ◽  
...  
Keyword(s):  
Risk Factor ◽  
Right Ventricular ◽  
Cox Regression ◽  
Jugular Vein ◽  
Right Ventricular Outflow Tract ◽  
Ventricular Outflow Tract ◽  
Outflow Tract ◽  
Cox Regression Analysis ◽  
Bovine Jugular Vein

Objectives: Conduits for reconstructing right ventricular outflow tract (RVOT) in children with congenital heart disease have evolved for better durability over the past decades, but conduits failure remains common. We designed decellularized and photooxidatively crosslinked bovine jugular vein conduit (DP-BJVC) and now aim to evaluate the midterm results of DP-BJVC for RVOT reconstruction.Methods: Ninety patients (median age: 4.2 years) undergoing RVOT reconstruction using DP-BJVC were prospectively followed for median of 4.7 years (range: 0.2–16.1 years). Kaplan–Meier analysis was used to examine the survival, freedom from conduit explantation and catheter-based reintervention. Risk factors were analyzed with Cox regression analysis.Results: Follow-up was completed in 92% of patients. There were five (5.6%) early deaths. The 10-year survival rate was 85.2%, with palliative procedure at DP-BJVC implantation as the risk factor. The 10-year freedom from conduit explantation and reintervention were 84.4 and 67.3% respectively, with previous cardiac operation as the only risk factor for explantation. Complications during the follow-up included conduit stenosis (peak gradient ≥50 mmHg) in 12 (12.9%), severe regurgitation in 2 (2.4%), and infective endocarditis in 2 (2.4%). The annual increase in gradient was highest in the first year (P = 0.003), but not appreciably afterwards. The echo-measured annulus diameter trends to increase by an average of 0.37 mm per year. Calcification appeared mild in the failed conduits.Conclusions: DP-BJVC provides satisfactory durability and functionality for RVOT reconstruction for children, with low morbidity of stenosis and endocarditis, as well as increase in diameter mildly with age in midterm follow-ups.

Right ventricular outflow tract reconstruction with valved bovine jugular vein conduit

2008 ◽  
Vol 56 (S 1) ◽  
Author(s):  
W Kuroczynski ◽  
C Kampmann ◽  
C Martin ◽  
M Heinemann ◽  
D Pruefer ◽  
...  
Keyword(s):  
Right Ventricular ◽  
Jugular Vein ◽  
Right Ventricular Outflow Tract ◽  
Ventricular Outflow Tract ◽  
Outflow Tract ◽  
Bovine Jugular Vein

Bovine Jugular Vein Conduit: A Mid- to Long-Term Institutional Review

2018 ◽  
Vol 9 (5) ◽  
pp. 489-495 ◽  
Author(s):  
Parth M. Patel ◽  
Corinne Tan ◽  
Nayan Srivastava ◽  
Jeremy L. Herrmann ◽  
Mark D. Rodefeld ◽  
...  
Keyword(s):  
Right Ventricular ◽  
Jugular Vein ◽  
Right Ventricular Outflow Tract ◽  
Ventricular Outflow Tract ◽  
Outflow Tract ◽  
Institutional Review ◽  
Group 2 ◽  
Bovine Jugular Vein ◽  
Group 1

Background: Since 1999, we have used the bovine jugular vein conduit for right ventricular outflow tract reconstruction in infants and children. Herein, we review their mid- to long-term outcomes. Methods: Between 1999 and 2016, 315 bovine jugular vein conduits were implanted in 276 patients. Patients were grouped by age at bovine jugular vein conduit implant: group 1: 0 to 1 years (N = 65), group 2: one to ten years (N = 132), and group 3: older than ten years (N = 118). For survival and hemodynamic analysis, additional group stratification was done based on conduit size. Group small: 12 and 14 mm (N = 75), group medium: 16 and 18 mm (N = 84), and group large: 20 and 22 mm (N = 156). Results: Mean follow-up for groups 1, 2, and 3 was 4.0, 4.9, and 5.9 years, respectively. Early mortality was 9%, 0%, and 1% for groups 1, 2, and 3, respectively ( P < .001). Late mortality was 5%, 2%, and 2% for groups 1, 2, and 3, respectively ( P = .337). Group 1 had the lowest ten-year freedom from conduit failure at 13%, versus 53% and 69% for groups 2 and 3, respectively ( P < .001). A total of 21 (6.6%) patients developed endocarditis, 11 (3.5%) patients required reoperation, and 10 (3.2%) patients required antibiotic therapy alone. Conclusions: The bovine jugular vein conduit is a useful option for right ventricular outflow tract reconstruction given its easy implantability and acceptable midterm durability.

P3651Outcomes of right ventricular outflow tract reconstruction in children: comparison between bovine jugular vein graft and expanded polytetrafluoroethylene graft

2019 ◽  
Vol 40 (Supplement_1) ◽  
Author(s):  
K Hirai ◽  
K Baba ◽  
T Goto ◽  
D Ousaka ◽  
H Oh ◽  
...  
Keyword(s):  
Right Ventricular ◽  
Vein Graft ◽  
Jugular Vein ◽  
Pulmonary Stenosis ◽  
Right Ventricular Outflow Tract ◽  
Ventricular Outflow Tract ◽  
Aneurysmal Dilatation ◽  
Expanded Polytetrafluoroethylene ◽  
Expanded Polytetrafluoroethylene Graft ◽  
Bovine Jugular Vein

Abstract Background Various types of conduits are available for right ventricular outflow tract reconstruction (RVOTR). The bovine jugular vein graft (BJVG) and expanded polytetrafluoroethylene graft (ePTFEG) have been descrived as an alternative to the homograft for RVOTR. Purpose- This study summarized the results to evaluate the single-center operation of RVOTR using BJVG and ePTFEG. Methods The valve functions of 27 patients under 20 years old who underwent primary RVOTR with BJVG and 26 patients with ePTFEG at our university hospital between 2013 and 2018 were retrospectively investigated. The valve conditions were assessed using echocardiography and cardiac catheterization. Results The median age at the time of operation was 1.8 years old (range, 6 days to 7.8 years old) with BJVG and 2.2 years old (range, 8 months to 9.1 years old) with ePTFEG. The median follow-up time was 3.4 years (range, 2 months to 5.2 years) with BJVG and 2.1 years (range, 1 month to 5.1 years) with ePTFEG. The peak RVOT gradient of BJVG was lower than ePTFEG (10.6±7.7 mmHg versus 18.1±16.2 mmHg, P=0.035). There were no differences in branch pulmonary stenosis defined as peak gradient up to 36mmHg (40.7% versus 50.0%, P=0.50) and pulmonary regurgitation graded worse than moderate (18.5% versus 11.5%, P=0.48) with BJVG and ePTFEG, respectively. Aneurysmal dilatation of the conduit was seen 22.2% with BJVG but none of patients with ePTFEG (P=0.01). All of patients with aneurysmal dilated BJVG had branch pulmonary stenosis. There were no differences in catheter intervention for branch pulmonary stenosis (22.2% versus 30.8%, P=0.48) and conduit replacement (11.1% versus 7.7%, log rank P=0.67) with BJVG and ePTFEG, respectively. There were no deaths during the fllow-up period in both groups. Conclusions The outcomes of RVOTR with BJVG and ePTFEG were clinically satisfactory. Aneurysmal dilatation was seen with BJVG and branch pulmonary stenosis was the risk factor for aneurysmal dilatation.

Early Results of the Bovine Jugular Vein Graft Used for Reconstruction of the Right Ventricular Outflow Tract

2005 ◽  
Vol 79 (2) ◽  
pp. 618-624 ◽  
Author(s):  
Hitendu H. Dave ◽  
Alexander Kadner ◽  
Felix Berger ◽  
Burkhardt Seifert ◽  
Ali Dodge-Khatami ◽  
...  
Keyword(s):  
Right Ventricular ◽  
Vein Graft ◽  
Jugular Vein ◽  
Right Ventricular Outflow Tract ◽  
Ventricular Outflow Tract ◽  
Outflow Tract ◽  
Early Results ◽  
Bovine Jugular Vein ◽  
The Right
Sign in / Sign up

Export Citation Format

Share Document