Acceleration of Phagocytosis in Human Neutrophils Incubated with Gabexate Mesilate

1994 ◽  
Vol 22 (5) ◽  
pp. 292-295 ◽  
Author(s):  
K Mikawa ◽  
H Akamatsu ◽  
N Maekawa ◽  
K Nishina ◽  
H Obara ◽  
...  
Keyword(s):  
Reactive Oxygen Species ◽  
Reactive Oxygen Species Production ◽  
Reactive Oxygen ◽  
Human Neutrophils ◽  
Dependent Manner ◽  
Oxygen Species ◽  
Gabexate Mesilate ◽  
Micro Organisms ◽  
Species Production

It has recently been shown that gabexate mesilate inhibited human neutrophil functions including chemotaxis and reactive oxygen species production. In the present study, the effects of gabexate mesilate on phagocytosis by human neutrophils in vitro were investigated. Gabexate mesilate significantly enhanced neutrophil phagocytosis in a dose-dependent manner. This characteristic of gabexate mesilate may facilitate protection against infecting micro-organisms, although the inhibition of reactive oxygen species production by neutrophils may be a disadvantage for host-defense against infection.

scholarly journals Nitroglycerine causes mitochondrial reactive oxygen species production: In vitro mechanistic insights

2007 ◽  
Vol 23 (12) ◽  
pp. 990-992 ◽  
Author(s):  
Tommaso Gori ◽  
Andreas Daiber ◽  
Giuseppe Di Stolfo ◽  
Silvia Sicuro ◽  
Saverio Dragoni ◽  
...  
Keyword(s):  
Reactive Oxygen Species ◽  
Reactive Oxygen Species Production ◽  
Reactive Oxygen ◽  
Oxygen Species ◽  
Mitochondrial Reactive Oxygen Species ◽  
Species Production

Effects of methoxylation of apocynin and analogs on the inhibition of reactive oxygen species production by stimulated human neutrophils

2001 ◽  
Vol 433 (2-3) ◽  
pp. 225-230 ◽  
Author(s):  
Edwin Van den Worm ◽  
Cees J Beukelman ◽  
Albert J.J Van den Berg ◽  
Burt H Kroes ◽  
Rudi P Labadie ◽  
...  
Keyword(s):  
Reactive Oxygen Species ◽  
Reactive Oxygen Species Production ◽  
Reactive Oxygen ◽  
Human Neutrophils ◽  
Oxygen Species ◽  
Species Production
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