scholarly journals Mesotheliomas of the Tunica Vaginalis Propria and Peritoneum in Fischer Rats

1977 ◽  
Vol 14 (4) ◽  
pp. 372-379 ◽  
Author(s):  
D. H. Gould

Nine mesotheliomas were found in a group of 384 mature, male, Fischer-derived rats maintained on various experimental diets in long-term feeding studies. The tumors apparently were unrelated to any of the test materials. They ranged from solid, raised serosal growths to delicate papillary structures, and occurred primarily on the tunica vaginalis propria of the testis, epididymis and spermatic cord. Four of the nine cases were unusual because there was mesotheliomatous involvement of the peritoneal as well as of the genital mesothelium.

Author(s):  
Charles L. Sanders ◽  
Roy R. Adee

Asbestos is a generic name for a group of hydrated mineral silicates that occur naturally in a fibrous form. The early interactions of asbestos fibers with alveolar cells in large part determines their long-term toxicity. Young adult, SPF, Fischer rats were given a single intratracheal instillation of 2 mg crocidolite asbestos suspended in 0.5 ml of 0.9% NaCl solution. About 80% of the fibers had lengths of less than 10 ym as measured on light micrographs of the fiber suspension. Two rats were killed at 3 hr, 1 d and 1, 4, 8, 12 and 16 wk after instillation and the lungs instilled with 8 ml McDowell - Trumps at 20 cm H2O. Lung tissue was dehydrated and sputtered coated with palladium-gold for SEM or post-fixed in osmium tetroxide, embedded in epoxy resin and sections stained with uranyl acetate and lead citrate for TEM.


1992 ◽  
Vol 21 (3) ◽  
pp. 253-255 ◽  
Author(s):  
Serdar Arda ◽  
M. Emin Şenocak ◽  
Nebil Büyükpamukçu ◽  
Akgün Hiçsônmeza ◽  
Safiye Göğüş

2004 ◽  
Vol 171 (4) ◽  
pp. 1625-1626 ◽  
Author(s):  
ETHAN G. POLSKY ◽  
CHARLES RAY ◽  
LOUIS D. DUBILIER

2019 ◽  
Vol 87 (2) ◽  
pp. 70-74 ◽  
Author(s):  
Usman M Haroon ◽  
Nikita R Bhatt ◽  
Ch Muhammad Akram ◽  
Hugh D Flood ◽  
Sibhasis K Giri

Introduction and objectives: Radical inguinal orchidectomy with ligation and division of the spermatic cord at the deep inguinal ring is the treatment of choice for testicular mass suspicious of cancer. In the era of organ preserving and minimally invasive surgery, it may be possible to propose a less radical sub-inguinal orchidectomy that may avoid the morbidity associated with opening the inguinal canal. The effect of this approach on oncological margins is not known. The aim of this article was to investigate the presence of spermatic cord involvement after a radical inguinal orchidectomy with a view to test feasibility of a modified sub-inguinal approach for testicular tumour excision. Materials and methods: A retrospective study on all orchidectomies performed for suspected testicular cancer was performed at a single hospital from over an 8-year period from January 2005 to December 2013. Non-cancerous lesions were excluded after histopathological review. All testicular malignancies were included and detailed histopathological review was performed. Results: A total of 121 orchidectomies were performed over the 8-year period. Three patients had spermatic cord involvement. Spermatic cord involvement did not adversely affect the outcome in these patients after a median follow-up of 5 years irrespective of tumour histology. The proximal spermatic cord was not involved in any testicular germ cell tumours on further cord sectioning, the only patient with proximal cord involvement had a B-cell lymphoma. Conclusion: We postulate that a sub-inguinal modified orchidectomy may be a less invasive alternative to radical inguinal orchidectomy, with comparable oncological outcomes based on low risk of spermatic cord involvement, which in itself is not a prognostic factor. We require further long-term follow-up studies on patients who have undergone this approach to validate the oncological outcomes and report the possible advantage of lower post-operative complications with this technique.


2014 ◽  
Vol 7 (1) ◽  
pp. 825 ◽  
Author(s):  
Odd V Höglund ◽  
Jessica Ingman ◽  
Fredrik Södersten ◽  
Kerstin Hansson ◽  
Niklas Borg ◽  
...  

1989 ◽  
Vol 46 (6) ◽  
pp. 928-931 ◽  
Author(s):  
Jan Hennsng L'abée-Lund

The spawning population of Atlantic salmon, Salmo salar, (mature male parr and adults (anadromous salmon)) were assessed in the River Baevra, central Norway, when the river was treated with rotenone in November 1986. The spawning population of adults consisted of 15 males and 19 females. The spawning population of males consisted of 167 mature male parr per adult male. The effective population size of adults was small; Na = 33.5 individuals. The presence of mature male parr theoretically increased the effective population size to Na = 71.7 individuals. This increase indicated that mature male parr brought the effective population size above a recommended minimum (Na = 50) to ensure long term viability.


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