scholarly journals An Examination of Comorbid Generalized Anxiety Disorder and Chronic Pain on Substance Misuse in a Canadian Population-Based Survey

2020 ◽  
Vol 65 (6) ◽  
pp. 418-425
Author(s):  
Elena Bilevicius ◽  
Jordana L. Sommer ◽  
Matthew T. Keough ◽  
Renée El-Gabalawy
Keyword(s):  
Chronic Pain ◽  
Back Pain ◽  
Anxiety Disorder ◽  
Generalized Anxiety Disorder ◽  
Substance Misuse ◽  
Population Based ◽  
Generalized Anxiety ◽  
Opioid Use ◽  
Canadian Population ◽  
Chronic Pain Conditions

Objectives: Chronic pain and generalized anxiety disorder (GAD) are co-occurring, and both conditions are independently associated with substance misuse. However, limited research has examined the impact of comorbid GAD and chronic pain on substance misuse. The aim of this article was to examine the associations between comorbid GAD and chronic pain conditions compared to GAD only with nonmedical opioid use, drug abuse/dependence, and alcohol abuse/dependence in a Canadian, population-based sample. Methods: Data came from the 2012 Canadian Community Health Survey–Mental Health ( N = 25,113). Multiple logistic regressions assessed the associations between comorbid GAD and chronic pain conditions (migraine, back pain, and arthritis) on substance misuse. Results: Comorbid GAD + back pain and GAD + migraine were associated with increased odds of nonmedical opioid use compared to GAD only. However, the relationship was no longer significant after controlling for additional chronic pain conditions. No significant relationship was found between GAD + chronic pain conditions with drug or alcohol abuse/dependence. Conclusions: Comorbid GAD + back pain and GAD + migraine have a unique association with nonmedical opioid use in Canadians compared to GAD only, and chronic pain multimorbidity may be driving this relationship. Results emphasize the need for screening for substance misuse and prescription access in the context of GAD and comorbid chronic pain.

scholarly journals Emotion sensitivity and self‐reported symptoms of generalized anxiety disorder across the lifespan: A population‐based sample approach

2019 ◽  
Vol 9 (6) ◽  
Author(s):  
Lauren A. Rutter ◽  
Luke Scheuer ◽  
Ipsit V. Vahia ◽  
Brent P. Forester ◽  
Jordan W. Smoller ◽  
...  
Keyword(s):  
Anxiety Disorder ◽  
Generalized Anxiety Disorder ◽  
Population Based ◽  
Generalized Anxiety

Generalized anxiety disorder and associated factors in adults in the Amazon, Brazil: A population-based study

2018 ◽  
Vol 236 ◽  
pp. 180-186 ◽  
Author(s):  
Marcus T. Silva ◽  
Mónica Caicedo Roa ◽  
Silvia S. Martins ◽  
Andréa Tenório Correia da Silva ◽  
Tais F. Galvao
Keyword(s):  
Anxiety Disorder ◽  
Generalized Anxiety Disorder ◽  
Associated Factors ◽  
Population Based ◽  
Generalized Anxiety ◽  
Population Based Study

scholarly journals Acute Pain Burden and Opioid Dose Requirements after Cesarean Delivery in Parturients with Preexisting Chronic Back Pain and Migraine

2021 ◽  
Vol 2021 ◽  
pp. 1-6
Author(s):  
Ryu Komatsu ◽  
Michael G. Nash ◽  
Kenneth C. Ruth ◽  
William Harbour ◽  
Taylor M. Ziga ◽  
...  
Keyword(s):  
Chronic Pain ◽  
Back Pain ◽  
Postoperative Pain ◽  
Pain Score ◽  
Cesarean Delivery ◽  
Chronic Back Pain ◽  
Weighted Average ◽  
Opioid Use ◽  
Opioid Dose ◽  
Chronic Pain Conditions

Introduction. Preexisting chronic pain has been reported to be a consistent risk factor for severe acute postoperative pain. However, each specific chronic pain condition has unique pathophysiology, and it is possible that the effect of each condition on postoperative pain is different. Methods. This is a retrospective cohort study of pregnant women with preexisting chronic pain conditions (i.e., migraine, chronic back pain, and the combination of migraine + chronic back pain), who underwent cesarean delivery. The effects of the three chronic pain conditions on time-weighted average (TWA) pain score (primary outcome) and opioid dose requirements in morphine milligram equivalents (MME) during postoperative 48 hours were compared. Results. The TWA pain score was similar in preexisting migraine and chronic back pain. Chronic back pain was associated with significantly greater opioid dose requirements than migraine (12.92 MME, 95% CI: 0.41 to 25.43, P = 0.041 ). Preoperative opioid use ( P < 0.001 ) was associated with a greater TWA pain score. Preoperative opioid use ( P < 0.001 ), smoking ( P = 0.004 ), and lower postoperative ibuprofen dose ( P = 0.002 ) were associated with greater opioid dose requirements. Conclusions. Findings suggest women with chronic back pain and migraine do not report different postpartum pain intensities; however, women with preexisting chronic back pain required 13 MME greater opioid dose than those with migraine during 48 hours after cesarean delivery.

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