scholarly journals Synthesis and Antiviral Activity of a Series of New Cyclohexenyl Nucleosides

2003 ◽  
Vol 14 (1) ◽  
pp. 31-37 ◽  
Author(s):  
Ping Gu ◽  
Jordi Morral ◽  
Jing Wang ◽  
Jef Rozenski ◽  
Roger Busson ◽  
...  

A series of new cyclohexenyl nucleosides is synthesized by coupling the heterocyclic bases with a protected cyclohexenyl precursor under Mitsunobu conditions. The compounds were evaluated for their antiviral and cytostatic activity. Pronounced activity against herpes simplex virus type 1 and type 2 was observed for the 2,6-diaminopurine analogue.

2016 ◽  
Vol 22 ◽  
pp. 422-430 ◽  
Author(s):  
Ayse Yildirim ◽  
Gulay Gulbol Duran ◽  
Nizami Duran ◽  
Kemal Jenedi ◽  
Behiye Sezgin Bolgul ◽  
...  

Virology ◽  
1988 ◽  
Vol 165 (2) ◽  
pp. 388-405 ◽  
Author(s):  
Wolfgang Hammerschmidt ◽  
Franz Conraths ◽  
Joachim Mankertzt ◽  
Georg Pauli ◽  
Hanns Ludwig ◽  
...  

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