scholarly journals Corrigendum to “Oxidative stress induced by cadmium in the plasma, erythrocytes and lymphocytes of rats: Attenuation by grape seed proanthocyanidins”

2020 ◽  
Vol 39 (8) ◽  
pp. 1130-1130
2015 ◽  
Vol 6 (7) ◽  
pp. 2179-2186 ◽  
Author(s):  
Chao-zong Lan ◽  
Ling Ding ◽  
Yi-lin Su ◽  
Kun Guo ◽  
Li Wang ◽  
...  

Renal dysfunction is one of the major effects of DOCA (deoxycorticosterone acetate)-salt hypertension and there is an increasing amount of evidence that oxidative stress damages the function of the kidney.


2002 ◽  
Vol 50 (26) ◽  
pp. 7720-7725 ◽  
Author(s):  
Fausta Natella ◽  
Federica Belelli ◽  
Vincenzo Gentili ◽  
Fulvio Ursini ◽  
Cristina Scaccini

2020 ◽  
Vol 47 (5) ◽  
pp. 3319-3330 ◽  
Author(s):  
Aline Fagundes Cerbaro ◽  
Victoria Soldatelli Borges Rodrigues ◽  
Marina Rigotti ◽  
Catia Santos Branco ◽  
Giovana Rech ◽  
...  

2019 ◽  
Vol 39 (1) ◽  
Author(s):  
Nazima Bashir ◽  
Kalist Shagirtha ◽  
Vaikundam Manoharan ◽  
Selvaraj Miltonprabu

Abstract The present study aims to evaluate the protective effect of grape seed proanthocyanidins (GSP) on cadmium (Cd)-induced testicular apoptosis, inflammation, and oxidative stress in rats. A total of 24 male Wistar rats were divided into four groups, namely control, GSP (100 mg/kg BW), Cd (5 mg/kg BW), and Cd+GSP. Cd-treated rat testes exhibited a significant increment in oxidative stress mediated inflammation and apoptosis. Pre-administration of GSP exhibit significant protection against the apoptotic and inflammatory damages elicited by Cd and uphold the intercellular antioxidant status in testes. Histological changes were studied and the immunohistochemical staining for caspase 3, HSP70, and eNOS protein expressions were also analyzed to justify the protective action of GSP. Furthermore, GSP prevented DNA damage, and enhanced the expression of antioxidant responsive elements Nrf2/HO-1 by PI3K/Akt-dependent pathway. Therefore, our results suggest that GSP acts as a multipotent antioxidant entity against Cd-induced oxidative testicular toxicity in rats.


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