scholarly journals Support from next of kin and nurses are significant predictors of long-term adherence to treatment in post-PCI patients

2019 ◽  
Vol 19 (4) ◽  
pp. 339-350 ◽  
Author(s):  
Outi Kähkönen ◽  
Helvi Kyngäs ◽  
Terhi Saaranen ◽  
Päivi Kankkunen ◽  
Heikki Miettinen ◽  
...  

Background: Adherence to treatment is a crucial factor in preventing the progression of coronary heart disease. More evidence of the predictors of long-term adherence is needed. Aims: The purpose of this study was to identify the predictive factors of adherence to treatment six years after percutaneous coronary intervention. Methods: Baseline data ( n=416) was collected in 2013 and follow-up data in 2019 ( n=169) at two university hospitals and three central hospitals in Finland. The self-reported Adherence of Patients with Chronic Disease Instrument was used. Data were analysed using descriptive statistics and binary logistic regression analysis. Results: The respondents reported higher adherence to a healthy lifestyle six years after percutaneous coronary intervention in comparison to four months post-percutaneous coronary intervention; adherence was seen in their healthy behaviour, such as decreased smoking and reduced alcohol consumption. Participating in regular follow-up control predicted adherence. Support from next of kin predicted physical activity and normal cholesterol levels; this outcome was associated with close relationships, which also predicted willingness to be responsible for treatment adherence. Women perceived lower support from nurses and physicians, and they had more fear of complications. Fear was more common among respondents with a longer duration of coronary heart disease. Physical activity and male gender were associated with perceived results of care. Conclusion: Support from next of kin, nurses and physicians, results of care, responsibility, fear of complication and continuum of care predicted adherence to treatment in long term. These issues should be emphasised among women, patients without a close relationship, physically inactive and those with a longer duration of coronary heart disease.

Circulation ◽  
2008 ◽  
Vol 118 (suppl_18) ◽  
Author(s):  
Pedro Carmo ◽  
Carlos Aguiar ◽  
Jorge Ferreira ◽  
Luis Raposo ◽  
Pedro Goncalves ◽  
...  

Purpose: N-terminal fragment of the B type-natriuretic peptide (NT-proBNP) is an established tool for assessing acute dyspnoea and stratifying risk in heart failure, acute coronary syndromes (ACS), and stable coronary heart disease (SCHD). The aim of this study was to determine the value of NT-proBNP in predicting long-term risk of patients (Pts) submitted to elective percutaneous coronary intervention (PCI) in the setting of SCHD. Methods: We prospectively studied 291 Pts (age 64.3±9.6 years, 64 female) with SCHD submitted to successful elective PCI, and determined NT-proBNP immediately before PCI. Pts were divided into 2 groups according to NT-proBNP level: group T3 formed by Pts with NT-proBNP level in the highest tertile and group T1+T2 formed by all remaining Pts. The study endpoint was time to the first occurrence of death (D) or non-fatal myocardial infarction (MI) during the mean follow-up of 568 ± 322 days. Multivariable analyses were performed to adjust the prognostic value of NT-proBNP for the effects of factors known to influence NT-proBNP (age, gender, renal function, body mass index) and of other potential predictors of outcome (cardiovascular risk factors, prior cardiovascular events, left ventricular ejection fraction, and PCI characteristics). Results: NT-proBNP ranged from 5 pg/ml to 104 pg/ml in the 1st tertile (T1), 105 pg/ml to 358 pg/ml in the 2nd tertile (T2), and 364 pg/ml to 33.991 pg/ml in the 3rd tertile (T3). During follow-up, 8 Pts died and 11 suffered a non-fatal MI. NT-proBNP was significantly higher in Pts who experienced an adverse outcome (440 pg/ml [inter-quartile range, 104 –1712] vs 174 pg/ml [inter-quartile range, 78 – 460) in Pts with uneventful follow-up; P= 0.007). An NT-proBNP level ≥364 pg/ml was associated with a higher endpoint rate (13.4% vs 3.1% in group T1+T2) and independently predicted outcome: adjusted hazard ratio 3.11, 95% CI, 1.15– 8.37, P=0.025. The sensitivity, specificity, predictive positive value, and negative predictive value for the criterion NT-proBNP ≥364 pg/ml were 68.4%, 69.1%, 13.4%, and 96.9%, respectively. Conclusion: In the setting of SCHD, the level of NT-proBNP is a powerful prognostic marker even after successful PCI.


Circulation ◽  
2007 ◽  
Vol 116 (suppl_16) ◽  
Author(s):  
Takayuki Ohno ◽  
Yoshihiro Suematsu ◽  
Noboru Motomura ◽  
Minoru Ono ◽  
Hideo Fujita ◽  
...  

Background : Coronary heart disease is the leading cause of death in diabetic population. Compared with diabetics without retinopathy, diabetics with retinopathy have an increased risk of myocardial infarction and death from coronary heart disease. Therefore, it is crucial to select an appropriate revascularization method in this considerable high-risk group. Methods: Between 1996 and 2004, a total of 149 patients with diabetic retinopathy underwent revascularization, either coronary artery bypass surgery (CABG) (n=56) or percutaneous coronary intervention with bare metal stents (BMS) (n=94). We compared overall survival rates of the two methods. Mortality was estimated according to Kaplan-Meier methods and was compared using the log-rank test. Results: The average follow-up from the time of the initial revascularization was 59.7 ± 33.3 months. During the entire follow-up, there was 8(14.5%)death in the CABG group and 27(28.7%) deaths in the BMS group. The average duration between death and revascularization was 81.3 ± 24.6 for the CABG group and 29.9 ± 23.8 for the BMS group (P<0.001). The 6-year overall survival was 94.8% for the CABG group and 73.6% for the BMS group. Mortality curves differed significantly between the two groups (P=0.004) (Figure ). After adjustment for baseline characteristics including age, sex, HbA1c, insulin, serum creatinine, ejection fraction, and the extent of coronary disease, the hazard ratio of death afforded by CABG was 0.36 (95% confidence interval, 0.15–0.87; P=0.023). Conclusions: In patients with diabetic retinopathy, CABG conferred survival benefit over BMS implantation.


2021 ◽  
Author(s):  
◽  
Artis Kalniņš ◽  

One of the methods for coronary heart disease (CHD) treatment is percutaneous coronary intervention (PCI). After the first successful percutaneous coronary angioplasty, done in 1977, PCI many years were performed only for patients with stable CHD. Since the early 1980s, PCI has also been used for acute myocardial infarction (MI) treatment. The benefits of invasive treatment over thrombolysis in acute MI had became clear already after the first studies (Keeley et al., 2003). Primary percutaneous coronary intervention is now undoubtedly the treatment of choice for the treatment of acute myocardial infarction (Ibanez et al., 2018). The usefulness and effectiveness of PCI in the treatment of chronic coronary heart disease, on the other hand, is constantly being discussed. Several studies have been performed trying to attempt to question the efficacy of PCI in the treatment of stable CHD (COURAGE, ORBITA). However, these studies have had a relatively short follow-up time and have not led to a limitation of PCI as a treatment method for stable CHD. A large proportion of CTO patients are asymptomatic and it is therefore even more difficult to demonstrate the benefits and advantages of invasive treatment for this group of patients. There are very few long-term follow-up studies that would prove efficacy or ineffectiveness of CTO invasive treatment, so the dissertation summarizes data and angioplasty results for 551 patients who underwent CTO PCI over 10 years.The aim of the study is to compare the long-term results of invasive treatment methods for patients with coronary heart disease and chronic total coronary artery occlusions. The dissertation compared the overall survival after successful and unsuccessful CTO PCI procedures, compared the long-term results of antegrade and retrograde percutaneous coronary intervention techniques, evaluated the multifactor effect of chronic total coronary artery occlusion complexity on the outcome of percutaneous coronary intervention and survival. Study also analyses PCI results for different groups of patients: with and without diabetes, before and after the age of 65, men and women, patients with and without a history of coronary artery bypass graft surgery.Comparing the long-term results after successful and unsuccessful CTO PCI procedures, a better survival was found after successful CTO PCI. Also has been found that the use of the retrograde approach improves the results of procedures and does not worsen the prognosis. It is concluded that in cases where successful antegrade CTO PCI is unlikely, the retrograde approach should be used as the primary strategy. It has been confirmed that the complexity of CTO, calculated by the J-CTO, PROGRESS CTO, CL and CASTLE scores, is directly correlated with the outcome of the procedure. The complexity of CTO, assessed by the PROGRESS CTO and CASTLE scales, can affect patient survival due to the complexity criteria included in these scales – quality of collaterals available for retrograde approach, age, and previous CABG.Analyses of different groups of patients have shown that CTO revascularization provides better survival in men than in women, the presence or absence of diabetes does not affect the long-term results of CTO PCI, for patients under and up to 65 years of age long term outcome after CTO PCI is not related to the patients age, but to the success of the procedure, patients with CTO and previous coronary artery bypass grafting should be considered as patients with increased complexity of CTO PCI.The obtained results provide recommendations for the CTO patients assesement and for CTO PCI procedure planning and performance.


2018 ◽  
Vol 27 (5-6) ◽  
pp. 989-1003 ◽  
Author(s):  
Outi Kähkönen ◽  
Terhi Saaranen ◽  
Päivi Kankkunen ◽  
Marja-Leena Lamidi ◽  
Helvi Kyngäs ◽  
...  

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