Factors Affecting Functional Outcome in Patients with Nontraumatic Spinal Cord Lesions After Inpatient Rehabilitation

2001 ◽  
Vol 15 (2) ◽  
pp. 99-104 ◽  
Author(s):  
J.J.M.F. van der Putten ◽  
V.L. Stevenson ◽  
E.D. Playford ◽  
A.J. Thompson

Objective: Patients with nontraumatic spinal cord lesions account for between one fourth and one half of all spinal cord injuries. In the management of this group of patients, an understanding of factors influencing functional improvement is essen tial to help define the most appropriate rehabilitation programme. Although it is pos sible to predict accurately the functional outcome for an individual patient with a com plete traumatic spinal cord injury, few studies have looked at prognostic factors in patients with nontraumatic spinal cord disease. The aim of this study was to determine which, and how well, factors assessed on admission to a rehabilitation unit relate to functional improvement in this group. Methods: The study sample consists of 100 patients with an incomplete nontraumatic spinal cord lesion who underwent inpatient neurorehabilitation. Possible prognostic factors were sought by identifying those vari ables with a significant difference in the Functional Independence Measure (FIM) motor change score above and below the median. A step-wise multiple regression analysis was then performed to determine which variables influenced functional out come. Results: Patients with larger functional gains had significantly lower disability scores on admission, a shorter time between symptom onset and rehabilitation, and a longer length of stay. They were more likely to have a cervical lesion and evidence of neurologic recovery. Multiple regression analysis demonstrated that the FIM motor score on admission and the time between symptom onset and rehabilitation predicted 54% of the variance of the FIM motor score gain. Conclusions: This finding suggests that early rehabilitation is an important factor in securing a good outcome. Key Words: Rehabilitation-Spinal cord lesion-Functional outcome.

2016 ◽  
Vol 4 (1) ◽  
pp. 26-36
Author(s):  
Evgeniya A Kochenova ◽  
Olga E Agranovich ◽  
Margarita V Savina

Introduction: Treatment of wrist contractures in children with arthrogryposis multiplex congenita (AMC) is extremely problematic because of the high incidence of recurrence. This study aimed to improve the outcome of wrist contracture treatment in children with AMC.Materials and Methods: A total of 90 patients (162 wrists) were examined and treated. Patients were assessed using a number of clinical, radiological, and electrophysiological examinations. There are several different clinical variants of wrist contracture, including flexion contracture of the wrist, flexion contracture associated with ulnar deviation, and isolated ulnar deviation of the wrist. Patients were divided into three groups according to the level of spinal cord lesion: С6-С7, С5-С8, and С5-Th1. As the number of damaged spinal cord segments increased, the amplitude of passive and active movements, degree of passive correction, muscle power, and wrist function decreased. Surgical treatment involved the following three approaches: tendon transfers, tendon transfers and carpal wedge osteotomy, and tendon transfers with carpal wedge osteotomy and shortened osteotomy of the forearm.Results: Analysis of treatment results showed that patients with segmental spinal cord lesions at the  С6-С7 and С5-С8 level were mostly associated with a good outcome, whereas patients with lesions at the  С5-Th1 level achieved satisfactory outcomes.Conclusions: Patients with segmental lesions of the spinal cord at the С6-С7 and С5-С8 level were associated with restoration of active wrist extension up to the neutral position or more and were expected to achieve significant improvement of hand function. Patients with spinal cord lesions at the C5-Th1 level exhibited significant lesions of the muscles, along with bone deformities. Consequently, surgical treatment could only achieve functional wrist position with minimal improvement of hand function. Using differential approaches in the treatment of wrist contracture that are selected by determining the level of spinal cord lesion will enable physicians to predict the outcome and improve the function and appearance of the wrist.


2014 ◽  
Vol 54 (7) ◽  
pp. 572-576 ◽  
Author(s):  
Shuichiro Neshige ◽  
Naoyuki Hara ◽  
Shinichi Takeshima ◽  
Hirotaka Iwaki ◽  
Yutaka Shimoe ◽  
...  

Injury ◽  
2015 ◽  
Vol 46 (8) ◽  
pp. 1539-1544 ◽  
Author(s):  
Mohsen Saffari ◽  
Amir H. Pakpour ◽  
Mohammad Yaghobidoot ◽  
Faten Al Zaben ◽  
Harold G. Koenige

2005 ◽  
Vol 94 (2) ◽  
pp. 934-942 ◽  
Author(s):  
N. L. Hansen ◽  
B. A. Conway ◽  
D. M. Halliday ◽  
S. Hansen ◽  
H. S. Pyndt ◽  
...  

It is possible to obtain information about the synaptic drive to motoneurons during walking by analyzing motor-unit coupling in the time and frequency domains. The purpose of the present study was to compare motor-unit coupling during walking in healthy subjects and patients with incomplete spinal cord lesion to obtain evidence of differences in the motoneuronal drive that result from the lesion. Such information is of importance for development of new strategies for gait restoration. Twenty patients with incomplete spinal cord lesion (SCL) participated in the study. Control experiments were performed in 11 healthy subjects. In all healthy subjects, short-term synchronization was evident in the discharge of tibialis anterior (TA) motor units during the swing phase of treadmill walking. This was identified from the presence of a narrow central peak in cumulant densities constructed from paired EMG recordings and from the presence of significant coherence between these signals in the 10- to 20-Hz band. Such indicators of short-term synchrony were either absent or very small in the patient group. The relationship between the amount of short-term synchrony and the magnitude of the 10- to 20-Hz coherence in the patients is discussed in relation to gait ability. It is suggested that supraspinal drive to the spinal cord is responsible for short-term synchrony and coherence in the 10- to 20-Hz frequency band during walking in healthy subjects. Absence or reduction of these features may serve as physiological markers of impaired supraspinal control of gait in SCL patients. Such markers could have diagnostic and prognostic value in relation to the recovery of locomotion in patients with central motor lesions.


Spinal Cord ◽  
2013 ◽  
Vol 51 (9) ◽  
pp. 688-693 ◽  
Author(s):  
G Lombardi ◽  
S Musco ◽  
M Celso ◽  
A Ierardi ◽  
F Nelli ◽  
...  

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