scholarly journals Percutaneous Transluminal Angioplasty for Atherosclerotic Stenoses of Intracranial Vessels

2004 ◽  
Vol 10 (2_suppl) ◽  
pp. 17-20 ◽  
Author(s):  
Y. Matsumaru ◽  
W. Tsuruta ◽  
T. Takigawa ◽  
A. Hyodo ◽  
H. Sato ◽  
...  
Keyword(s):  
Percutaneous Transluminal Angioplasty ◽  
Cerebral Arteries ◽  
Transluminal Angioplasty ◽  
Morbidity Rate ◽  
Term Outcome ◽  
Long Term Outcome ◽  
Middle Cerebral Arteries ◽  
Basilar Arteries ◽  
Percutaneous Transluminal

To study the efficacy and long-term outcome of percutaneous transluminal angioplasty (PTA) with/without stent placement for intracranial atherosclerotic stenoses, we reviewed our treated cases retrospectively. Between May 1992 and October 2003, PTA with/without stents was performed in 64 intracranial and skull base vessels in 62 patients, including 24 middle cerebral arteries, 16 internal carotid arteries, 13 vertebral arteries, and 11 basilar arteries. PTA was technically successful in 55 vessels (86%). However, four vessels (6%) failed to achieve satisfactory dilatation. We encountered five periprocedural strokes as symptomatic complications, for a mortality rate of 4.7% and a morbidity rate of 3.1%. All the patients with stent placements survived angioplasty without any complication. In the clinical follow-up available for one week to 11.5 years (mean, 4.7 years), there were three strokes related to the treated vessels. The annual stroke rate in the affected territory was estimated at 1.2% per year. According to these results, PTA for intracranial atherosclerotic stenoses seems to be a beneficial therapy for immediate anatomical results and long-term stroke prevention. Stent-assisted PTA could help patients achieve successful dilatation and avoid complications.

Percutaneous transluminal angioplasty of infrainguinal vein graft stenosis: Long-term outcome

1995 ◽  
Vol 82 (7) ◽  
pp. 1003-1004
Author(s):  
A. D. Houghton ◽  
M. R. Tyrrell ◽  
Y. Panayiotopoulos ◽  
J. F. Reidy ◽  
P. R. Taylor ◽  
...  
Keyword(s):  
Vein Graft ◽  
Percutaneous Transluminal Angioplasty ◽  
Transluminal Angioplasty ◽  
Term Outcome ◽  
Long Term Outcome ◽  
Graft Stenosis ◽  
Percutaneous Transluminal

Long-term Outcome of Infrainguinal Percutaneous Transluminal Angioplasty

2004 ◽  
Vol 11 (3) ◽  
pp. 287-293 ◽  
Author(s):  
Carl-Magnus Wahlgren ◽  
Bo Kalin ◽  
Kent Lund ◽  
Jesper Swedenborg ◽  
Rabbe Takolander
Keyword(s):  
Percutaneous Transluminal Angioplasty ◽  
Transluminal Angioplasty ◽  
Term Outcome ◽  
Long Term Outcome ◽  
Percutaneous Transluminal

Percutaneous transluminal angioplasty of infrainguinal vein graft stenosis: Long—term outcome

1995 ◽  
Vol 82 (2) ◽  
pp. 204-206 ◽  
Author(s):  
P. Dunlop ◽  
K. Varty ◽  
T. Hartshorne ◽  
P. R. F. Bell ◽  
A. Bolia ◽  
...  
Keyword(s):  
Vein Graft ◽  
Percutaneous Transluminal Angioplasty ◽  
Transluminal Angioplasty ◽  
Term Outcome ◽  
Long Term Outcome ◽  
Graft Stenosis ◽  
Percutaneous Transluminal

Abstract 6053: Long-Term Outcome of Percutaneous Transluminal Angioplasty in Chronic Hemodialysis Patients with Peripheral Arterial Disease

Circulation ◽  
2008 ◽  
Vol 118 (suppl_18) ◽  
Author(s):  
Toru Aoyama ◽  
Hideki Ishii ◽  
Miho Tanaka ◽  
Hiroshi Takahashi ◽  
Yoshihiro Kawamura ◽  
...  
Keyword(s):  
Percutaneous Transluminal Angioplasty ◽  
Major Amputation ◽  
Transluminal Angioplasty ◽  
Chronic Hemodialysis ◽  
Term Outcome ◽  
Long Term Outcome ◽  
Increased Risk ◽  
Artery Disease ◽  
Percutaneous Transluminal

Chronic hemodialysis (HD) patients are at an increased risk for peripheral artery disease (PAD). Although percutaneous transluminal angioplasty (PTA) has become a widely used therapeutic intervention for PAD, its outcome in HD patients remains poorly understood. The aim of this study was to clarify the long-term outcome after PTA in HD patients with PAD. Consecutive 241 HD patients with 418 lesions and 152 non-HD patients with 201 lesions who underwent successful PTA as a first-choice therapeutic option for PAD were enrolled. They were followed for 8 years. Outcome measures included target lesion revascularization (TLR), major amputation, and all-cause mortality. Mean age was younger and prevalence of coronary artery disease and femoropopliteal lesion were significantly more frequent in HD patients (66±10years vs. 71±10years, p=0.0001, 52% vs. 41%, p=0.035 and 71% vs. 52%, p=0.0002, respectively). Prevalence of critical limb ischemia and TASC C+D lesion types were comparable in both groups (45% vs. 34% and 37% vs. 38%, respectively). During 46±38months, the 8-year freedom from TLR (64% vs. 76%, p=0.0057) limb salvage (82% vs. 97%, p=0.0001) and survival rates (52% vs. 87%, p<0.0001) were significantly lower in HD patients, respectively. On Cox multivariate analysis, HD status was strongly predictive of major amputation (HR 4.69, 95%CI 1.34 –16.39, p=0.015) and all-cause death (HR 5.13, 95%CI 2.14 –12.35, p=0.0002) but not of TLR (HR 1.54, 95%CI 0.85–2.78, p=0.15). In HD patients, ulceration/gangrene were independent predictors for all outcome (HR 2.50, 95%CI 1.22–5.09, p=0.0003 for TLR, HR 6.71, 95%CI 2.78 –16.13, p<0.0001 for amputation, and HR 1.95, 95%CI 1.11– 4.20, p=0.017 for all-cause death, respectively). Additional stenting was an independent predictor to reduce TLR in HD patients (HR 0.51, 95%CI 0.28 – 0.94, p=0.031). The long-term outcome after PTA was still poorer in HD patients compared with non-HD patients, but it might be acceptable in HD patients. Ulceration/gangrene was deeply associated with any outcome, thus, the detection at the earlier stage of PAD is important in this population who are at the highest risk for arteriosclerosis. Additional stenting was useful to reduce TLR.

Percutaneous Transluminal Angioplasty for Atherosclerotic Stenosis of the Intracranial Cerebral Arteries

1999 ◽  
Vol 5 (1_suppl) ◽  
pp. 27-32 ◽  
Author(s):  
A. Hyodo ◽  
N. Kato ◽  
Y. Nakai ◽  
I. Anno ◽  
H. Sato ◽  
...  
Keyword(s):  
Skull Base ◽  
Cerebral Artery ◽  
Percutaneous Transluminal Angioplasty ◽  
Cerebral Arteries ◽  
Transluminal Angioplasty ◽  
Term Survival ◽  
Number Of Patients ◽  
Percutaneous Transluminal

Percutaneous transluminal angioplasty (PTA) was carried out 52 times for 49 lesions in 47 cases of atheroscrelotic stenosis of the intracranial or skull base cerebral arteries. The stenotic lesions involved the middle cerebral artery in 21 cases, the basilar artery in eight cases, the internal carotid artery (petrous-supraclinoid portion) in 15 cases, and the intracranial vertebral artery in five cases. Nearly all cases were symptomatic, such as TIA or stroke, and the degree of stenosis ranged from 70 to 99 percent, with a mean of 80 percent. PTA was performed using a STEALTH balloon angioplasty catheter. In these trials, PTA was successfully performed (as indicated by a residual stenosis under 50%) 41 times. The initial success rate was 79% and stenosis was reduced from 80% to 25%. Clinical follow-up was performed from 7 to 84 months with a mean of 44 months. During this period, death due to myocardial infarction or pneumonia occurred in five cases, stroke related to previous PTA occurred in one case (due to re-stenosis) and stroke unrelated to previous PTA occurred in two cases. Angiographic follow-up was performed in 31 cases after 41 successful PTA procedures. Re-stenosis was seen in 20% of the cases, symptomatic complications occurred in 6%, and asymptomatic complications occurred in 6% of the cases. One case suffered severe subarachnoid hemorrhage just after the PTA due to preexisting aneurysm rupture and he died a week after the PTA. So mortality in this series was 2%. From the results described here, we may conclude that PTA of the intracranial or skull base cerebral artery is technically feasible, and it can be performed with relatively low risk. From our results, it may be a useful method and effective for long-term survival of patients. But results from a larger number of patients and more long-term follow-up data are still necessary in order to evaluate the safety and usefulness of this method.

Klinische Langzeitergebnisse der perkutanen transluminalen Angioplastie bei Patienten mit peripherer arterieller Verschlusskrankheit

VASA ◽  
2002 ◽  
Vol 31 (1) ◽  
pp. 36-42 ◽  
Author(s):  
. Bucek ◽  
Hudak ◽  
Schnürer ◽  
Ahmadi ◽  
Wolfram ◽  
...  
Keyword(s):  
Success Rate ◽  
Clinical Stage ◽  
Ankle Brachial Index ◽  
Clinical Situation ◽  
Clinical Results ◽  
Transluminal Angioplasty ◽  
Term Outcome ◽  
Long Term Outcome

Background: We investigated the long-term clinical results of percutaneous transluminal angioplasty (PTA) in patients with peripheral arterial occlusive disease (PAOD) and the influence of different parameters on the primary success rate, the rate of complications and the long-term outcome. Patients and methods: We reviewed clinical and hemodynamic follow-up data of 166 consecutive patients treated with PTA in 1987 in our department. Results: PTA improved the clinical situation in 79.4% of patients with iliac lesions and in 88.3% of patients with femoro-popliteal lesions. The clinical stage and ankle brachial index (ABI) post-interventional could be improved significantly (each P < 0,001), the same results were observed at the end of follow-up (each P < 0,001). Major complications occurred in 11 patients (6.6%). The rate of primary clinical long-term success for suprainguinal lesions was 55% and 38% after 5 and 10 years (femoro-popliteal 44% and 33%), respectively, the corresponding data for secondary clinical long-term success were 63% and 56% (60% and 55%). Older age (P = 0,017) and lower ABI pre-interventional (P = 0,019) significantly deteriorated primary clinical long-term success for suprainguinal lesions, while no factor could be identified influencing the outcome of femoro-popliteal lesions significantly. Conclusion: Besides an acceptable success rate with a low rate of severe complications, our results demonstrate favourable long-term clinical results of PTA in patients with PAOD.

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