Determination of Estrogen and Progesterone Receptors in Human Breast Cancer Cytosols: A Comparison between Radioligand Binding Assay (DCC) and Enzyme Immunoassay (EIA)

1996 ◽  
Vol 11 (1) ◽  
pp. 50-52
Author(s):  
M. Cerra ◽  
L. Cecco ◽  
M. Montella ◽  
E. Celentano ◽  
P. Bonelli ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Enzyme Immunoassay ◽  
Human Breast Cancer ◽  
Binding Assay ◽  
Radioligand Binding ◽  
Progesterone Receptors ◽  
Radioligand Binding Assay ◽  
Human Breast ◽  
Estrogen And Progesterone Receptors

Determination of Estrogen Receptors in Human Breast Cancer: Comparison between Enzyme Immunoassay and Dextran-Coated Charcoal Method

1986 ◽  
Vol 72 (5) ◽  
pp. 511-514 ◽  
Author(s):  
Cecilia Bozzetti ◽  
Nadia Naldi ◽  
Annamaria Guazzi ◽  
Rita Nizzoli ◽  
Magda Benecchi ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Estrogen Receptor ◽  
Estrogen Receptors ◽  
Enzyme Immunoassay ◽  
Strong Correlation ◽  
Human Breast Cancer ◽  
Human Breast ◽  
Dextran Coated Charcoal ◽  
The Mean

Estrogen receptor determination was performed on 120 breast cancer cytosols, using the dextran-coated charcoal method (DCC) and an enzyme immunoassay (EIA) to compare the efficiency of the two techniques. A strong correlation was noted between ER concentrations determined by DCC and EIA (P < 0.001). The mean ER-EIA value was significantly higher than the mean ER-DCC value in premenopausal (P < 0.001) as well in postmenopausal (P < 0.001) patients.

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