Re: MM Al-Qattan. Wnt pathways and upper limb anomalies. J Hand Surg Eur. 2011, 36: 9–22.

2011 ◽  
Vol 36 (5) ◽  
pp. 434-434
Author(s):  
Kerby C. Oberg
Keyword(s):  
Upper Limb ◽  
Limb Anomalies ◽  
Wnt Pathways

WNT pathways and upper limb anomalies

2010 ◽  
Vol 36 (1) ◽  
pp. 9-22 ◽  
Author(s):  
M. M. Al-Qattan
Keyword(s):  
Upper Limb ◽  
Wnt Pathway ◽  
Apical Ectodermal Ridge ◽  
Joint Development ◽  
Limb Anomalies ◽  
Dorsal Ectoderm ◽  
Wnt Pathways ◽  
Nail Patella Syndrome ◽  
The Relationship ◽  
Duplication Syndrome

The various Wnt pathways that are related to upper limb anomalies are reviewed. Abnormalities in the Wnt7a pathway (located in the dorsal ectoderm) produce several clinically relevant conditions such as the palmar duplication syndrome, nail patella syndrome, ulnar ray deficiency, limb hypoplasia, polysyndactyly and the palmar nail syndrome. Abnormalities of the Wnt3/3a pathway (located in the apical ectodermal ridge) include tetra-amelia and loss of the distal phalanges/nails. Abnormalities of the Wnt5/5a pathway (located in the apical ectodermal ridge as well as in the mesoderm) will affect chondrogenesis of the developing limb and experimental Wnt5a−/− limbs have terminal adactyly. Chondrogenesis and limb muscle differentiation are both affected by several Wnt pathways and these will be reviewed in details. Abnormalities in LRP 5/6 (a co-receptor for Wnts) lead to congenital bone disease and Wnt4 is specifically involved in joint development. Finally, the relationship between the Wnt pathway and SALL4 (mutations of which cause Okihiro/Duane-radial ray deficiency in humans) are discussed.

Genetic Basis of Congenital Upper Limb Anomalies: Analysis of 487 Cases of a Specialized Clinic

2013 ◽  
Vol 97 (12) ◽  
pp. 798-805 ◽  
Author(s):  
Diana Carli ◽  
Tracy Fairplay ◽  
Paola Ferrari ◽  
Silvana Sartini ◽  
Mario Lando ◽  
...  
Keyword(s):  
Upper Limb ◽  
Genetic Basis ◽  
Limb Anomalies

scholarly journals Documenting Combined Congenital Upper Limb Anomalies Using the Oberg, Manske, and Tonkin Classification: Implications for Epidemiological Research and Outcome Comparisons

2018 ◽  
Vol 43 (9) ◽  
pp. 869.e1-869.e11 ◽  
Author(s):  
Martijn Baas ◽  
Pieter R. Zwanenburg ◽  
Steven E.R. Hovius ◽  
Christianne A. van Nieuwenhoven
Keyword(s):  
Upper Limb ◽  
Epidemiological Research ◽  
Limb Anomalies

Convergent Validity of PODCI and PROMIS Domains in Congenital Upper Limb Anomalies

2020 ◽  
Vol 45 (1) ◽  
pp. 33-40 ◽  
Author(s):  
Lindley B. Wall ◽  
Carley Vuillermin ◽  
Patricia E. Miller ◽  
Donald S. Bae ◽  
Charles A. Goldfarb
Keyword(s):  
Upper Limb ◽  
Convergent Validity ◽  
Limb Anomalies

Upper limb anomalies and renal disease

2008 ◽  
Vol 17 (2) ◽  
pp. 117-119 ◽  
Author(s):  
Richard L. Siegler ◽  
Paul Larsen ◽  
Bruce A. Buehler
Keyword(s):  
Renal Disease ◽  
Upper Limb ◽  
Limb Anomalies

Hand and Upper Limb Anomalies in Poland Syndrome

2012 ◽  
Vol 32 (7) ◽  
pp. 722-726 ◽  
Author(s):  
Nunzio Catena ◽  
Maria T. Divizia ◽  
Maria G. Calevo ◽  
Anwar Baban ◽  
Michele Torre ◽  
...  
Keyword(s):  
Upper Limb ◽  
Poland Syndrome ◽  
Limb Anomalies

scholarly journals Advances in understanding the genetics of syndromes involving congenital upper limb anomalies

2019 ◽  
Vol 4 ◽  
pp. 30-30 ◽  
Author(s):  
Liying Sun ◽  
Yingzhao Huang ◽  
Sen Zhao ◽  
Wenyao Zhong ◽  
Mao Lin ◽  
...  
Keyword(s):  
Upper Limb ◽  
Limb Anomalies
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