scholarly journals Corrigendum to “Diagnosing small fiber neuropathy in clinical practice: a deep phenotyping study”

2021 ◽  
Vol 14 ◽  
pp. 175628642110366
Keyword(s):  
Clinical Practice ◽  
Small Fiber Neuropathy ◽  
Small Fiber ◽  
Deep Phenotyping

1. Laser evoked potential in clinical practice: The diagnostic field in small fiber neuropathy

2017 ◽  
Vol 128 (12) ◽  
pp. e415
Author(s):  
G. Devigili ◽  
S. Rinaldo ◽  
C. Lettieri ◽  
R. Eleopra
Keyword(s):  
Clinical Practice ◽  
Evoked Potential ◽  
Small Fiber Neuropathy ◽  
Small Fiber

Erythromelalgia Linked to Small Fiber Neuropathy

2006 ◽  
Vol 37 (5) ◽  
pp. 38
Author(s):  
JANE SALODOF MACNEIL
Keyword(s):  
Small Fiber Neuropathy ◽  
Small Fiber

Schmerz-Evozierte Potentiale: Eine neue Methode in der Diagnostik der small-fiber neuropathy bei HIV-positiven Patienten

2004 ◽  
Vol 31 (S 1) ◽  
Author(s):  
Z Katsarava ◽  
Ö Yaldizli ◽  
C Voulkoudis ◽  
S Esser ◽  
HC Diener ◽  
...  
Keyword(s):  
Small Fiber Neuropathy ◽  
Small Fiber ◽  
Evozierte Potentiale

Neuropathic Pain in Small Fiber Neuropathy

2019 ◽  
pp. 153-164
Author(s):  
Ming-Chang Chiang ◽  
Paul-Chen Hsieh ◽  
Sung-Tsang Hsieh
Keyword(s):  
Neuropathic Pain ◽  
Small Fiber Neuropathy ◽  
Small Fiber

scholarly journals Diagnosing small fiber neuropathy in clinical practice: a deep phenotyping study

2021 ◽  
Vol 14 ◽  
pp. 175628642110043
Author(s):  
Nadine Egenolf ◽  
Caren Meyer zu Altenschildesche ◽  
Luisa Kreß ◽  
Katja Eggermann ◽  
Barbara Namer ◽  
...  
Keyword(s):  
Neurological Examination ◽  
Punch Biopsy ◽  
Small Fiber Neuropathy ◽  
Fiber Density ◽  
Axon Reflex ◽  
Small Fiber ◽  
Corneal Confocal Microscopy ◽  
Intraepidermal Nerve Fiber Density ◽  
Number Of Patients ◽  
Skin Punch Biopsy

Background and aims: Small fiber neuropathy (SFN) is increasingly suspected in patients with pain of uncertain origin, and making the diagnosis remains a challenge lacking a diagnostic gold standard. Methods: In this case–control study, we prospectively recruited 86 patients with a medical history and clinical phenotype suggestive of SFN. Patients underwent neurological examination, quantitative sensory testing (QST), and distal and proximal skin punch biopsy, and were tested for pain-associated gene loci. Fifty-five of these patients additionally underwent pain-related evoked potentials (PREP), corneal confocal microscopy (CCM), and a quantitative sudomotor axon reflex test (QSART). Results: Abnormal distal intraepidermal nerve fiber density (IENFD) (60/86, 70%) and neurological examination (53/86, 62%) most frequently reflected small fiber disease. Adding CCM and/or PREP further increased the number of patients with small fiber impairment to 47/55 (85%). Genetic testing revealed potentially pathogenic gene variants in 14/86 (16%) index patients. QST, QSART, and proximal IENFD were of lower impact. Conclusion: We propose to diagnose SFN primarily based on the results of neurological examination and distal IENFD, with more detailed phenotyping in specialized centers.

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