scholarly journals Synthesis of ε-Viniferin Glycosides by Glucosyltransferase from Phytolacca americana and their Inhibitory Activity on Histamine Release from Rat Peritoneal Mast Cells

2015 ◽  
Vol 10 (6) ◽  
pp. 1934578X1501000 ◽  
Author(s):  
Hiroki Hamada ◽  
Hatsuyuki Hamada ◽  
Kei Shimoda
Keyword(s):  
Mast Cells ◽  
Histamine Release ◽  
Inhibitory Activity ◽  
Phytolacca Americana ◽  
Peritoneal Mast Cells ◽  
Rat Peritoneal Mast Cells ◽  
Inhibitory Activities

Glycosylation of (+)-ε-viniferin was investigated using glucosyltransferase from Phytolacca americana ( PaGT3) as a biocatalyst. (+)-ε-Viniferin was converted by PaGT3 into its 4b- and 13b-β-D-glucosides, the inhibitory activities on histamine release from rat peritoneal mast cells of which were higher than that of (+)-ε-viniferin.

scholarly journals Biotransformation of Daidzein to Diadzein-7-Glucoside and Its Anti-allergic Activity

2017 ◽  
Vol 12 (11) ◽  
pp. 1934578X1701201 ◽  
Author(s):  
Yuya Fujitaka ◽  
Kei Shimoda ◽  
Minami Araki ◽  
Shouta Doi ◽  
Tsubasa Ono ◽  
...  
Keyword(s):  
Mast Cells ◽  
Histamine Release ◽  
Inhibitory Activity ◽  
Plant Cells ◽  
The Other ◽  
Phytolacca Americana ◽  
Other Hand ◽  
Peritoneal Mast Cells ◽  
Rat Peritoneal Mast Cells

The biotransformation of daidzein and its diacetate was investigated using cultured plant cells of Phytolacca americana as biocatalysts. Daidzein was glucosylated to the corresponding 7- O-β-D-glucoside. On the other hand, daidzein diacetate was hydrolyzed to daidzein, which was further glucosylated to 7- O-β-D-glucoside with much higher yield in comparison with the biotransformation of daidzein. Daidzein 7- O-β-D-glucoside showed higher inhibitory activity for histamine release from rat peritoneal mast cells than daidzein.

Platelet factor 4 fragment induces histamine release from rat peritoneal mast cells

Peptides ◽  
2002 ◽  
Vol 23 (10) ◽  
pp. 1713-1717 ◽  
Author(s):  
Ryujiro Suzuki ◽  
Tomoki Kimura ◽  
Kiyoyuki Kitaichi ◽  
Yasuaki Tatsumi ◽  
Miyoko Matsushima ◽  
...  
Keyword(s):  
Mast Cells ◽  
Histamine Release ◽  
Platelet Factor 4 ◽  
Platelet Factor ◽  
Peritoneal Mast Cells ◽  
Rat Peritoneal Mast Cells

scholarly journals Enzymatic Synthesis and Anti-Allergic Activities of Curcumin Oligosaccharides

2010 ◽  
Vol 3 ◽  
pp. BCI.S2768 ◽  
Author(s):  
Kei Shimoda ◽  
Hiroki Hamada
Keyword(s):  
Mast Cells ◽  
Histamine Release ◽  
Enzymatic Synthesis ◽  
Antibody Formation ◽  
Cyclodextrin Glucanotransferase ◽  
Enzymatic Method ◽  
Inhibitory Effects ◽  
Peritoneal Mast Cells ◽  
Rat Peritoneal Mast Cells ◽  
Suppressive Action

Curcumin 4‘- O-glucooligosaccharides were synthesized by a two step-enzymatic method using almond β-glucosidase and cyclodextrin glucanotransferase (CGTase). Curcumin was glucosylated to curcumin 4‘- O-β-D-glucopyranoside by almond β-glucosidase in 19% yield. Curcumin 4‘- O-β-D-glucopyranoside was converted into curcumin 4‘- O-β-glucooligosaccharides, i.e. 4‘- O-β-maltoside (51%) and 4‘- O-β-maltotrioside (25%), by further CGTase-catalyzed glycosylation. Curcumin 4‘- O-β-glycosides showed suppressive action on IgE antibody formation and inhibitory effects on histamine release from rat peritoneal mast cells.

Enhancement of Histamine Release from Rat Peritoneal Mast Cells Exposed to Formaldehyde

1992 ◽  
Vol 4 (2) ◽  
pp. 125-136 ◽  
Author(s):  
Hidekazu Fujimaki ◽  
Fujio Shiraishi ◽  
Noboru Katayama
Keyword(s):  
Mast Cells ◽  
Histamine Release ◽  
Peritoneal Mast Cells ◽  
Rat Peritoneal Mast Cells
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