Clinical, MR Imaging and MR Spectroscopy Findings in Cohen Syndrome

We describe a 20-year-old, non-Finnish man with Cohen syndrome (MIM: 216550). Besides the essential clinical and MR imaging findings including non-progressive psychomotor retardation, motor clumsiness, microcephaly, typical facial features, retinochoroidal dystrophy, myopia and thick corpus callosum, he also had infertility, pituitary hyperplasia and low-lying tentorium. No diffusion changes were recorded. MR spectroscopy (40 and 270 ms TE) revealed normal spectra.

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Acute infarct of the corpus callosum: Appearance on diffusion-weighted MR imaging and MR spectroscopy

Journal of Magnetic Resonance Imaging ◽

10.1002/jmri.10348 ◽

2003 ◽

Vol 18 (2) ◽

pp. 255-259 ◽

Cited By ~ 8

Author(s):

Gerard Riedy ◽

Elias R. Melhem

Keyword(s):

Corpus Callosum ◽

Mr Imaging ◽

Mr Spectroscopy ◽

Diffusion Weighted ◽

Acute Infarct

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Central neurocytoma: proton MR spectroscopy and diffusion weighted MR imaging findings

Magnetic Resonance Imaging ◽

10.1016/j.mri.2008.07.012 ◽

2009 ◽

Vol 27 (3) ◽

pp. 434-440 ◽

Cited By ~ 30

Author(s):

Murat Kocaoglu ◽

Fatih Ors ◽

Nail Bulakbasi ◽

Onder Onguru ◽

Cuneyt Ulutin ◽

...

Keyword(s):

Mr Imaging ◽

Mr Spectroscopy ◽

Central Neurocytoma ◽

Imaging Findings ◽

Proton Mr Spectroscopy ◽

Diffusion Weighted ◽

And Diffusion

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van der Knaap syndrome: MR imaging findings including FLAIR, diffusion imaging, and proton MR spectroscopy

European Radiology ◽

10.1007/s003300000324 ◽

2000 ◽

Vol 10 (9) ◽

pp. 1452-1455 ◽

Cited By ~ 13

Author(s):

R. N. Sener

Keyword(s):

Mr Imaging ◽

Mr Spectroscopy ◽

Diffusion Imaging ◽

Imaging Findings ◽

Proton Mr Spectroscopy

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Neuroaxonal dystrophy: MR imaging, proton MR spectroscopy, and diffusion MR imaging findings

Journal of Neuroradiology ◽

10.1016/s0150-9861(06)77546-0 ◽

2006 ◽

Vol 33 (3) ◽

pp. 207-208 ◽

Cited By ~ 1

Author(s):

H. Mutlu ◽

H.O. Sildiroglu ◽

G. Sonmez ◽

E. Ozturk ◽

E. Kizilkaya

Keyword(s):

Mr Imaging ◽

Mr Spectroscopy ◽

Neuroaxonal Dystrophy ◽

Imaging Findings ◽

Proton Mr Spectroscopy ◽

Diffusion Mr ◽

And Diffusion ◽

Diffusion Mr Imaging

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MR Spectroscopy and Perfusion MR Imaging Findings of Intracranial Foreign Body Granuloma: a Case Report

Korean Journal of Radiology ◽

10.3348/kjr.2010.11.3.359 ◽

2010 ◽

Vol 11 (3) ◽

pp. 359 ◽

Cited By ~ 10

Author(s):

Seung Won Jang ◽

Sang Joon Kim ◽

Sun Mi Kim ◽

Jeong Hyun Lee ◽

Choong Gon Choi ◽

...

Keyword(s):

Case Report ◽

Foreign Body ◽

Mr Imaging ◽

Mr Spectroscopy ◽

Foreign Body Granuloma ◽

Imaging Findings ◽

Intracranial Foreign Body ◽

Perfusion Mr ◽

Perfusion Mr Imaging

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Glioblastoma multiforme with diffusion-weighted magnetic resonance imaging characteristics mimicking primary brain lymphoma

Journal of Neurosurgery ◽

10.3171/jns.2006.105.1.132 ◽

2006 ◽

Vol 105 (1) ◽

pp. 132-135 ◽

Cited By ~ 25

Author(s):

Cheng-Hong Toh ◽

Yao-Liang Chen ◽

Tsung-Che Hsieh ◽

Shih-Ming Jung ◽

Ho-Fai Wong ◽

...

Keyword(s):

Glioblastoma Multiforme ◽

Magnetic Resonance ◽

Corpus Callosum ◽

Mr Imaging ◽

Mr Spectroscopy ◽

Water Restriction ◽

Mr Images ◽

Brain Lymphoma ◽

Diffusion Weighted ◽

Primary Brain Lymphoma

✓ The authors report on the first case of corpus callosum glioblastoma multiforme (GBM) with diffusion-weighted (DW) magnetic resonance (MR) imaging findings that mimicked those for lymphoma but with MR spectroscopy results absent of lymphoma characteristics. This 68-year-old man presented with rapid, progressive impairment in short-term memory as well as slow responses and a change in his personality within 3 weeks of admission. Results of cranial computed tomography revealed a slightly hyperdense corpus callosum tumor with bihemispheric involvement. Magnetic resonance images showed a homogeneous mass with strong enhancement. The mass showed water restriction on DW MR images and apparent diffusion coefficient (ADC) maps but no markedly elevated lipid resonance on MR spectroscopy. The patient underwent tumor resection. Results of pathological studies with immunohistochemical analysis confirmed that the lesion was GBM. Diffusion-weighted MR imaging together with ADC mapping and MR spectroscopy was reported to be useful in differentiating GBM and primary brain lymphoma. The lymphomas were hyperintense to gray matter on DW MR images and isointense to hypointense on ADC maps because of water restriction. In contrast, the GBMs were hyperintense to gray matter on both DW MR images and ADC maps because of the T2 shine-through effect. On MR spectroscopy, lipid resonance was markedly elevated in lymphoma but only slightly elevated in GBM.

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