Acute infarct of the corpus callosum: Appearance on diffusion-weighted MR imaging and MR spectroscopy

✓ The authors report on the first case of corpus callosum glioblastoma multiforme (GBM) with diffusion-weighted (DW) magnetic resonance (MR) imaging findings that mimicked those for lymphoma but with MR spectroscopy results absent of lymphoma characteristics. This 68-year-old man presented with rapid, progressive impairment in short-term memory as well as slow responses and a change in his personality within 3 weeks of admission. Results of cranial computed tomography revealed a slightly hyperdense corpus callosum tumor with bihemispheric involvement. Magnetic resonance images showed a homogeneous mass with strong enhancement. The mass showed water restriction on DW MR images and apparent diffusion coefficient (ADC) maps but no markedly elevated lipid resonance on MR spectroscopy. The patient underwent tumor resection. Results of pathological studies with immunohistochemical analysis confirmed that the lesion was GBM. Diffusion-weighted MR imaging together with ADC mapping and MR spectroscopy was reported to be useful in differentiating GBM and primary brain lymphoma. The lymphomas were hyperintense to gray matter on DW MR images and isointense to hypointense on ADC maps because of water restriction. In contrast, the GBMs were hyperintense to gray matter on both DW MR images and ADC maps because of the T2 shine-through effect. On MR spectroscopy, lipid resonance was markedly elevated in lymphoma but only slightly elevated in GBM.

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Abstract P2-02-03: Multiparametric MR imaging of the breast with dynamic contrast-enhanced MR imaging, diffusion-weighted imaging and proton MR spectroscopy: Are all three parameters necessary for accurate breast cancer diagnosis?

10.1158/0008-5472.sabcs13-p2-02-03 ◽

2013 ◽

Author(s):

K Pinker-Domenig ◽

W Bogner ◽

S Gruber ◽

PC Dubsky ◽

Z Bago-Horvath ◽

...

Keyword(s):

Breast Cancer ◽

Mr Imaging ◽

Cancer Diagnosis ◽

Mr Spectroscopy ◽

Diffusion Weighted Imaging ◽

Breast Cancer Diagnosis ◽

Proton Mr Spectroscopy ◽

Dynamic Contrast Enhanced ◽

Diffusion Weighted ◽

Contrast Enhanced

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Minimal hepatic encephalopathy in children with liver cirrhosis: diffusion-weighted MR imaging and proton MR spectroscopy of the brain

Neuroradiology ◽

10.1007/s00234-014-1409-0 ◽

2014 ◽

Vol 56 (10) ◽

pp. 885-891 ◽

Cited By ~ 22

Author(s):

Ahmed Abdel Khalek Abdel Razek ◽

Ahmed Abdalla ◽

Amany Ezzat ◽

Ahmed Megahed ◽

Tarek Barakat

Keyword(s):

Liver Cirrhosis ◽

Hepatic Encephalopathy ◽

Mr Imaging ◽

Mr Spectroscopy ◽

Minimal Hepatic Encephalopathy ◽

Proton Mr Spectroscopy ◽

Diffusion Weighted ◽

The Brain

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Clinical, MR Imaging and MR Spectroscopy Findings in Cohen Syndrome

Rivista di Neuroradiologia ◽

10.1177/197140090501800114 ◽

2005 ◽

Vol 18 (1) ◽

pp. 82-86

Author(s):

N. Bulakbasi ◽

S. Ilkbahar ◽

M. Kocaoglu

Keyword(s):

Corpus Callosum ◽

Mr Imaging ◽

Mr Spectroscopy ◽

Psychomotor Retardation ◽

Facial Features ◽

Imaging Findings ◽

Cohen Syndrome ◽

Pituitary Hyperplasia

We describe a 20-year-old, non-Finnish man with Cohen syndrome (MIM: 216550). Besides the essential clinical and MR imaging findings including non-progressive psychomotor retardation, motor clumsiness, microcephaly, typical facial features, retinochoroidal dystrophy, myopia and thick corpus callosum, he also had infertility, pituitary hyperplasia and low-lying tentorium. No diffusion changes were recorded. MR spectroscopy (40 and 270 ms TE) revealed normal spectra.

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