scholarly journals Choriocarcinoma metastatic to the skin: A rare occurrence associated with dismal outcome

Rare Tumors ◽  
2021 ◽  
Vol 13 ◽  
pp. 203636132110397
Author(s):  
Mousa ElKhaldi ◽  
Rakan Radi ◽  
Maysa Al-Hussaini
Keyword(s):  
Back Pain ◽  
Germ Cell ◽  
Lower Back Pain ◽  
Germ Cell Tumors ◽  
Cutaneous Metastasis ◽  
Hematogenous Metastasis ◽  
Rare Occurrence ◽  
Lower Back ◽  
Embryonic Gonad ◽  
Work Up

Germ cell tumors (GCTs) are a histologically heterogeneous group of tumors that arise from the primitive germ cell of the embryonic gonad. Choriocarcinoma is a variant of GCTs that is prone to hematogenous metastasis to the liver, lung, and brain. Cutaneous metastasis in choriocarcinoma is rarely encountered with only a few cases reported in literature. We report the case of a 28-year-old male presenting with lower back pain that, upon further work-up, was diagnosed with pure choriocarcinoma of the testes. Around 9 months after his initial presentation, he developed a cutaneous back lesion. Microscopic examination confirmed the presence of choriocarcinoma composed of mononuclear cytotrophoblasts which interweave with multinucleated syncytiotrophoblasts. The patient passed away 3 weeks after the onset of cutaneous metastasis.

scholarly journals A Case of Rare Cutaneous Metastasis from Advanced Pancreatic Cancer

2020 ◽  
Vol 13 (1) ◽  
pp. 49-54 ◽  
Author(s):  
Hiroyuki Ito ◽  
Takuma Tajiri ◽  
Shin-ichiro Hiraiwa ◽  
Tomoko Sugiyama ◽  
Ayano Ito ◽  
...  
Keyword(s):  
Pancreatic Cancer ◽  
Back Pain ◽  
Bone Metastases ◽  
Pancreatic Adenocarcinoma ◽  
Lower Back Pain ◽  
Advanced Pancreatic Cancer ◽  
Cutaneous Metastasis ◽  
Lower Back ◽  
Imaging Results ◽  
The Right

A 71-year-old woman presented to a nearby hospital with an occipital scalp ulcer with exudate. Thoracoabdominal enhanced computed tomography (CT) was performed due to suspected cancer. The imaging results showed tumors in the pancreatic tail and at multiple sites in the lung, whereupon she was referred to our hospital for further investigation. Histological analysis of the occipital scalp ulcer and the pancreatic tumor led to the diagnosis of pancreatic adenocarcinoma with cutaneous metastasis and multiple lung metastases. Combination chemotherapy (gemcitabine and nab-paclitaxel) was started, and about 4 months later the patient experienced right lower back pain. Abdominal CT showed partial sclerosis of the right iliac bone and multiple spinal lesions, which were diagnosed as multiple bone metastases. Narcotic analgesia was started for the right lower back pain. Since then, FOLFIRINOX has been introduced as second-line chemotherapy against tumor growth, and treatment has been ongoing for 10 months since the initial chemotherapy. Pancreatic cancer is a rapidly growing cancer and can show early metastasis to other organs, lymph node metastasis, and peritoneal dissemination; therefore, the prognosis of pancreatic cancer is very poor. Cutaneous metastasis from pancreatic cancer is rare, and only a few cases have been reported. Here, we report an unusual case of pancreatic adenocarcinoma with cutaneous metastasis and multiple lung and bone metastases.

Panel Approves Duloxetine for Lower Back Pain

2010 ◽  
Vol 38 (9) ◽  
pp. 24
Author(s):  
ELIZABETH MECHCATIE
Keyword(s):  
Back Pain ◽  
Lower Back Pain ◽  
Lower Back

Knowledge of lower back pain by selected demographic variables among clinical students in Abha, Saudi Arabia

2020 ◽  
pp. 1801-1805
Author(s):  
Ibrahim Alburaidi ◽  
Khaled Alravie ◽  
Saleh Qahtani ◽  
Hani Dibssan ◽  
Nawaf Abdulhadi ◽  
...  
Keyword(s):  
Saudi Arabia ◽  
Back Pain ◽  
Lower Back Pain ◽  
Demographic Variables ◽  
Lower Back

scholarly journals Glioma with Leptomeningeal Spread Mimics Chronic Meningoencephalitis in a Young Adult

2021 ◽  
pp. 179-183
Author(s):  
Ann-Kristin Becker ◽  
Marta Leonora Frank ◽  
Michael Friese ◽  
Joachim Röther
Keyword(s):  
Brain Tumor ◽  
Back Pain ◽  
Young Adult ◽  
Lower Back Pain ◽  
Low Grade Glioma ◽  
Low Grade ◽  
Who Grade ◽  
Leptomeningeal Spread ◽  
Lower Back ◽  
Uncommon Case

The most malignant type of intrinsic brain tumor is glioblastoma (WHO grade IV). Primary leptomeningeal spread is rare and leads to a variety of differential considerations, as there is no typical clinical or imaging pattern. Here we present a rare and uncommon case of a primary leptomeningeal glioblastoma in combination with a low-grade glioma in a 21-year-old male, initially presenting with only headache and lower back pain. The presented case illustrates the challenging differential considerations and the severe course of leptomeningeal glioblastomas.

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