scholarly journals Iatrogenic ocular trauma associated with infraorbital block performed for rhinoscopy in a cat: case report and preliminary imaging findings

2021 ◽  
Vol 7 (1) ◽  
pp. 205511692110114
Author(s):  
Stephanie A Pumphrey ◽  
Rebecca C Reader ◽  
Diana S Rosenstein ◽  
Pamela J Mouser ◽  
Lois A Wetmore

Objectives This paper describes a case of endophthalmitis in a feline patient caused by globe penetration during an infraorbital block performed to provide analgesia during rhinoscopy, and presents additional imaging and dissection data demonstrating risk of iatrogenic ocular trauma during infraorbital blocks in cats when the infraorbital canal is entered. Methods Case records and accompanying histopathologic reports were reviewed for the feline patient. Separately, two feline cadavers were imaged using CT following placement of 5/8" 25 G needles or 1" 22 G over the needle catheters in the infraorbital canal. Infraorbital blocks with injection of trypan blue dye followed by dissection were performed in two further feline cadavers to assess the potential for globe penetration and to provide preliminary information regarding the potential efficacy of infraorbital blocks for analgesia during rhinoscopy. Results Clinical and histopathologic findings support inadvertent globe penetration during infraorbital block as the cause for endophthalmitis in the feline patient described. CT imaging and dye injection studies further demonstrate the risks involved with this local anesthetic technique in cats. Conclusions and relevance Further study is needed to assess the safety and efficacy of infraorbital blocks performed for rhinoscopy in cats. Catheters may be safer anesthetic delivery devices than needles. Extreme caution should be used when entering the infraorbital canal in cats.

1993 ◽  
Vol 21 (3) ◽  
pp. 324-329
Author(s):  
Jeffrey R. Fry ◽  
Alison H. Hammond

A variety of approaches to assessment of cellular integrity exist, based on tests of integrity of the plasma membrane, tests of metabolic competence, and asessment of morphology. By definition, such approaches address different aspects of cellular integrity and hence are not interchangeable indices of cellular integrity. Accordingly, it would be most appropriate to characterise hepatocyte preparations on the basis of more than just trypan blue dye exclusion (a test of plasma membrane integrity) as is customary. A scheme for the choice of the most appropriate mix of tests of cellular integrity is presented.


2003 ◽  
Vol 29 (9) ◽  
pp. 1733-1737 ◽  
Author(s):  
Jagjit S. Saini ◽  
Arun K. Jain ◽  
Jaspreet Sukhija ◽  
Poonam Gupta ◽  
Vandana Saroha

Cornea ◽  
2020 ◽  
Vol 39 (11) ◽  
pp. e26
Author(s):  
Pawan Prasher ◽  
Brahmjot Singh ◽  
Kanwardeep Singh
Keyword(s):  

1993 ◽  
Vol 9 (6) ◽  
pp. 671-674 ◽  
Author(s):  
Steven A. Altman ◽  
Lisa Randers ◽  
Govind Rao

2021 ◽  
Author(s):  
Seav-Ly Tran ◽  
Andrea Puhar ◽  
Maud Ngo-Camus ◽  
Nalini Ramarao

Trypan Blue Dye Enters Viable Cells Incubated with the Pore-Forming Toxin HlyII of Bacillus cereus


In Vitro ◽  
1981 ◽  
Vol 17 (12) ◽  
pp. 1100-1110 ◽  
Author(s):  
Hugo O. Jauregui ◽  
Nancy T. Hayner ◽  
James L. Driscoll ◽  
Rhonda Williams-Holland ◽  
Milton H. Lipsky ◽  
...  

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