The gap between basic science research and clinical application has long existed and therefore translational research has emerged in recent years to bridge such gap. Consortium for Translational Orthodontic Research (CTOR) was established with missions to integrate resources from different entities and to provide a platform for interdisciplinary groups who share the same vision to exchange ideas and inspire innovations. During its short existence, CTOR has successfully carried out several research projects which led to various innovations. Micro-osteoperforation is by far one of the most successful examples of translational research in the orthodontic field. It exemplifies how translational research can benefit scientists, clinicians, and patients. In this article, the process of its development, the rationale and scientific evidence from animal and clinical studies, and how it can be applied in daily practice will be depicted.
Translational research in oral oncology – A bridge between basic science and clinical application
