scholarly journals Role of anthracycline and comprehensive geriatric assessment for elderly patients with diffuse large B-cell lymphoma

Blood ◽  
2017 ◽  
Vol 130 (20) ◽  
pp. 2180-2185 ◽  
Author(s):  
Richard J. Lin ◽  
Madhusmita Behera ◽  
Catherine S. Diefenbach ◽  
Christopher R. Flowers
Keyword(s):  
Elderly Patients ◽  
B Cell ◽  
Geriatric Assessment ◽  
Comprehensive Geriatric Assessment ◽  
Cell Lymphoma ◽  
Treatment Decision ◽  
B Cell Lymphoma ◽  
Treatment Decision Making ◽  
Large B Cell Lymphoma ◽  
Large B Cell

Abstract Survival outcome for elderly patients with newly diagnosed diffuse large B-cell lymphoma remains suboptimal in the rituximab era. In this systematic review, we summarize available evidence relevant to the inclusion of anthracycline in upfront chemoimmunotherapy for these elderly patients and highlight the need of prospective clinical trials. With limited prospective data, we find that pretreatment comprehensive geriatric assessment accurately predicts survival and treatment-related toxicities, suggesting its potential role in guiding overall treatment decision-making.

scholarly journals Modulated Chemotherapy According to Modified Comprehensive Geriatric Assessment in 100 Consecutive Elderly Patients with Diffuse Large B‐Cell Lymphoma

2012 ◽  
Vol 17 (6) ◽  
pp. 838-846 ◽  
Author(s):  
Michele Spina ◽  
Monica Balzarotti ◽  
Lilj Uziel ◽  
Andrés José Marìa Ferreri ◽  
Lucia Fratino ◽  
...  
Keyword(s):  
Elderly Patients ◽  
B Cell ◽  
Geriatric Assessment ◽  
Comprehensive Geriatric Assessment ◽  
Cell Lymphoma ◽  
B Cell Lymphoma ◽  
Large B Cell Lymphoma ◽  
Large B Cell
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