Incidence of chest infections (CI) in patients with neuromuscular disease (NMD) in the first 2 weeks after commencement of Non-invasive Ventilation (NIV) or Mechanical In-Exsufflation (MI-E)

Author(s):  
Liam Campbell ◽  
Ben Messer
Author(s):  
Cristina Puricelli ◽  
Eleonora Volpato ◽  
Salvatore Sciurello ◽  
Antonello Nicolini ◽  
Paolo Banfi

he standard treatment for patients with neuromuscular respiratory failure is non-invasive ventilation (NIV) as non-invasive ventilation support-setting (NVS). NVS is administered through a nasal or face mask and/or mouthpiece with the potential to cause nasal ulcers, discomfort, and/or aesthetic issues, resulting in poor compliance. We reported the observation of a 45-year-old woman with limb-girdle muscular dystrophy (LGMD), secondary to Dysferlin deficiency, who was on NVS since 2017 for nocturnal hypoventilation. In 2018, despite nocturnal ventilation, due to weight gain and daytime hypoventilation, a nasal mask was introduced. We initiated daytime intermittent abdominal pressure ventilation (IAPV) to mitigate cosmetic problems, improving in pO2 and decreasing in pCO2 versus baseline (52>84 mmHg, 46>33 mmHg respectively) at 6 (85 mmHg, 42 mmHg) and 18 months (93 mmHg, 38 mmHg), respectively. IAPV was effective, safe, and well-tolerated in our patients who did not tolerate standard daytime NVS with the known interface.


Respirology ◽  
2013 ◽  
Vol 19 (1) ◽  
pp. 80-84 ◽  
Author(s):  
Raffaele Falsaperla ◽  
Anette Wenzel ◽  
Piero Pavone ◽  
Caterina Di Mauro ◽  
Giovanna Vitaliti

2020 ◽  
Vol 8 ◽  
Author(s):  
Brigitte Fauroux ◽  
Sonia Khirani ◽  
Lucie Griffon ◽  
Theo Teng ◽  
Agathe Lanzeray ◽  
...  

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