scholarly journals Factors affecting the transient hyperaemic response test of the cerebral autoregulation

Critical Care ◽  
2010 ◽  
Vol 14 (Suppl 1) ◽  
pp. P350
Author(s):  
MS Sitina ◽  
V Cerny
Keyword(s):  
Cerebral Autoregulation ◽  
Factors Affecting ◽  
Response Test ◽  
Hyperaemic Response

scholarly journals Factors affecting assessment of cerebral autoregulation using the transient hyperaemic response test

1998 ◽  
Vol 81 (3) ◽  
pp. 317-321 ◽  
Author(s):  
G Cavill ◽  
E J Simpson ◽  
R P Mahajan
Keyword(s):  
Cerebral Autoregulation ◽  
Factors Affecting ◽  
Response Test ◽  
Hyperaemic Response

Computerised transient hyperaemic response test—A method for the assessment of cerebral autoregulation

1995 ◽  
Vol 21 (5) ◽  
pp. 599-611 ◽  
Author(s):  
Piotr Smielewski ◽  
Marek Czosnyka ◽  
Vijay Iyer ◽  
Stefan Piechnik ◽  
Helen Whitehouse ◽  
...  
Keyword(s):  
Cerebral Autoregulation ◽  
Response Test ◽  
Hyperaemic Response

Characteristics of the transient hyperaemic response test to assess skin vascular reactivity

2001 ◽  
Vol 18 (Supplement 21) ◽  
pp. 35
Author(s):  
S. M. Hancock ◽  
M. Malik ◽  
R. P. Mahajan
Keyword(s):  
Vascular Reactivity ◽  
Response Test ◽  
Hyperaemic Response

Evaluation of the transient hyperemic response test in head-injured patients

1997 ◽  
Vol 86 (5) ◽  
pp. 773-778 ◽  
Author(s):  
Piotr Smielewski ◽  
Marek Czosnyka ◽  
Peter Kirkpatrick ◽  
John D. Pickard
Keyword(s):  
Flow Velocity ◽  
Clinical Condition ◽  
Cerebral Autoregulation ◽  
Injured Patient ◽  
Content Type ◽  
Response Test ◽  
Arterial Blood ◽  
Head Injured ◽  
Hyperemic Response ◽  
Fine Print

✓ The transient hyperemic response test has been shown to provide an index of cerebral autoregulation in healthy individuals and in patients who have suffered a subarachnoid hemorrhage. In this study, the test was applied to patients who had received a severe head injury, and the value of the test was assessed by comparing its result with the individual's clinical condition (Glasgow Coma Scale [GCS] score), cerebral perfusion pressure (CPP), transcranial Doppler wave form—derived index for cerebral autoregulation (relationship between the CPP and the middle cerebral artery flow velocity), and outcome (Glasgow Outcome Scale [GOS] score). Forty-seven patients, aged 16 to 63 years, with head injuries were included in the study. Signals of intracranial pressure, arterial blood pressure, flow velocity, and cortical microcirculatory flux were digitized and recorded for a period of 30 minutes using special computer software. Two carotid compressions were performed at the beginning of each recording. The transient hyperemic response ratio (THRR: the ratio of the hyperemic flow velocity recorded after carotid release and the precompression baseline flow velocity) was calculated, as was the correlation coefficient Sx used to describe the relationship between slow fluctuations in the systolic flow velocity and CPP throughout the period of recording. No significant changes in CPP were found during compression. There was a significant correlation between the THRR and the Sx (r = 0.49, p < 0.0001). The hyperemic response proved to be lower in patients who exhibited a poor clinical grade at presentation (GCS scores < 6, p = 0.01) and lower in patients achieving a poor outcome (GOS scores of 3, 4, and 5, p = 0.003). Loss of postcompression hyperemia occurred when the CPP fell below 50 mm Hg. The carotid compression test provides a simple index of cerebral autoregulation that is relevant to the clinical condition and outcome of the severely head injured patient.

Sign in / Sign up

Export Citation Format

Share Document