scholarly journals Failure of reversion of neuromuscular block with sugammadex in patient with myasthenia gravis: case report and brief review of literature

2019 ◽  
Vol 19 (1) ◽  
Author(s):  
Hermann dos Santos Fernandes ◽  
Jorge Luiz Saraiva Ximenes ◽  
Daniel Ibanhes Nunes ◽  
Hazem Adel Ashmawi ◽  
Joaquim Edson Vieira
2021 ◽  
Vol 14 (12) ◽  
pp. e246005
Author(s):  
Louise Gurowich ◽  
Gabriel Yiin ◽  
Adam Maxwell ◽  
Alexandra Rice

Myasthenia gravis (MG) is an autoimmune condition affecting the neuromuscular junction characterised by weakness and fatiguability, carrying a high morbidity if treatment is delayed. A clear association with thymoma has led to management with thymectomy as a common practice, but MG presenting post-thymectomy has rarely been reported. We present a case of an 82- year-old woman developing fatigue, ptosis and dysarthria 3 months after thymectomy. After a clinical diagnosis of MG was made, she responded well to prompt treatment with prednisolone and pyridostigmine. Her anti-acetylcholine receptor antibody (anti-AChR) subsequently came back positive. Our systematic review reveals that post-thymectomy MG can be categorised as early-onset or late-onset form with differing aetiology, and demonstrated correlation between preoperative anti-AChR titres and post-thymectomy MG. The postulated mechanisms for post-thymectomy MG centre around long-lasting peripheral autoantibodies. Clinicians should actively look for MG symptoms in thymoma patients and measure anti-AChR preoperatively to aid prognostication.


1970 ◽  
Vol 13 (1) ◽  
pp. 109-114
Author(s):  
MA Hannan ◽  
Mohammad Sayeed Hassan ◽  
Ayesha Begum ◽  
AKM Nurul Kabir

Myasthenia Gravis (MG) is a rare disease of neuromuscular junction which typically presents with fatigable weakness of cranial and limb muscles. But patient may present with vague symptoms which may mislead physicians to an incorrect diagnosis. We are reporting a 45 year old cobbler presented with the complaints of lack of energy, aching pain in shoulder, back, upper arm and difficulty in swallowing of both solid and liquid food without any diurnal variation for two and half years. He was ultimately diagnosed as a case of MG and thymectomy revealed thymoma. DOI: http://dx.doi.org/10.3329/jom.v13i1.10087 JOM 2012; 13(1): 109-114


2012 ◽  
Vol 12 (1) ◽  
pp. 103-108
Author(s):  
Abdullah Al-Asmi ◽  
Ramachandiran Nandhagopal ◽  
P C Jacob ◽  
Arunodaya Gujjar

2020 ◽  
Vol 65 (4) ◽  
pp. 1350-1353
Author(s):  
Harshwardhan K. Khartade ◽  
Vikas P. Meshram ◽  
Nilesh K. Tumram ◽  
Manoj B. Parchake ◽  
Harish M. Pathak

2006 ◽  
Vol 3 (1) ◽  
pp. 55-57 ◽  
Author(s):  
S Dwarakanath ◽  
S Gopal ◽  
R Satish ◽  
NK Venkataramana

2009 ◽  
Author(s):  
S.R.K. Naik ◽  
S. Kang ◽  
Ch. Ling ◽  
Regina

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