scholarly journals Effectiveness, safety, and factors associated with the clinical success of endoscopic biliary drainage for patients with hepatocellular carcinoma: a retrospective multicenter study

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Akihiro Matsumi ◽  
Hironari Kato ◽  
Toru Ueki ◽  
Etsuji Ishida ◽  
Masahiro Takatani ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Obstructive Jaundice ◽  
Liver Dysfunction ◽  
Biliary Drainage ◽  
Clinical Success ◽  
Survival Duration ◽  
Clinical Failure ◽  
Endoscopic Biliary Drainage ◽  
Technical Success ◽  
Factors Associated

Abstract Background Only a few reports have assessed the effectiveness of endoscopic biliary drainage (EBD) in hepatocellular carcinoma (HCC) patients with obstructive jaundice and liver dysfunction. Methods This was a retrospective study based on the clinical databases from the Okayama University Hospital and 10 affiliated hospitals. All patients received EBD for jaundice or liver dysfunction. The indication for EBD was aggravation of jaundice or liver dysfunction with intrahepatic bile duct (IHBD) dilation. The technical and clinical success rate, complications, factors associated with clinical failure, and survival duration were evaluated. Results A total of 107 patients were enrolled in this study. Technical success was achieved in 105 of 107 patients (98.1%). Clinical success was achieved in 85 of 105 patients (81%). Complications related to endoscopic retrograde cholangiography (ERC) occurred in 3 (2.8%) patients. Child–Pugh class C (odds ratio 3.90, 95% confidence interval [CI] 1.47–10.4, p = 0.0046) was the only factor associated with clinical failure, irrespective of successful drainage. The median survival duration was significantly longer in patients with clinical success than in those without clinical success (5.0 months vs. 0.93 months; hazard ratio [HR] 3.2, 95% CI 1.87–5.37). HCC Stage I/II/III (HR 0.57, CI 0.34–0.95, p = 0.032), absence of portal thrombosis (HR 0.52, CI 0.32–0.85, p = 0.0099), and clinical success (HR 0.39, CI 0.21–0.70, p = 0.0018) were significant factors associated with a long survival. Conclusions EBD for obstructive jaundice and liver dysfunction in patients with HCC can be performed safely with a high technical success rate. Clinical success can improve the survival duration, even in patients expected to have a poor prognosis. Trial registration Retrospectively registered.

Effectiveness of endoscopic biliary drainage for unresectable hepatocellular carcinoma associated with obstructive jaundice

2001 ◽  
Vol 36 (3) ◽  
pp. 173-180 ◽  
Author(s):  
Kazuhiro Matsueda ◽  
Hiroshi Yamamoto ◽  
Fumi Umeoka ◽  
Toru Ueki ◽  
Takeshi Matsumura ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Obstructive Jaundice ◽  
Biliary Drainage ◽  
Endoscopic Biliary Drainage ◽  
Unresectable Hepatocellular Carcinoma

scholarly journals Two cases of successfully treated after endoscopic biliary drainage for obstructive jaundice in hepatocellular carcinoma

2010 ◽  
Vol 76 (2) ◽  
pp. 130-131
Author(s):  
Kensuke Kuraoka ◽  
Masato Matsuyama ◽  
Seigo Yukisawa ◽  
Koichi Takano ◽  
Hiroshi Ishii ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Obstructive Jaundice ◽  
Biliary Drainage ◽  
Endoscopic Biliary Drainage

scholarly journals How to Choose Between Percutaneous Transhepatic and Endoscopic Biliary Drainage in Malignant Obstructive Jaundice: An Updated Systematic Review and Meta-analysis

In Vivo ◽  
2020 ◽  
Vol 34 (4) ◽  
pp. 1701-1714
Author(s):  
ALESSANDRO RIZZO ◽  
ANGELA DALIA RICCI ◽  
GIORGIO FREGA ◽  
ANDREA PALLONI ◽  
STEFANIA DE LORENZO ◽  
...  
Keyword(s):  
Systematic Review ◽  
Obstructive Jaundice ◽  
Biliary Drainage ◽  
Meta Analysis ◽  
Endoscopic Biliary Drainage ◽  
Malignant Obstructive Jaundice

scholarly journals Prolonged international normalized ratio and vascular injury at divisional level predict embolization failures of patients with iatrogenic renal vascular injuries

2019 ◽  
Vol 9 (1) ◽  
Author(s):  
Shen-Yang Lee ◽  
Mei-Lin Wang ◽  
Yon-Cheong Wong ◽  
Cheng-Hsian Wu ◽  
Li-Jen Wang
Keyword(s):  
Vascular Injury ◽  
Clinical Success ◽  
Arterial Embolization ◽  
International Normalized Ratio ◽  
Technical Failure ◽  
Clinical Failure ◽  
Technical Success ◽  
Inadequate Information ◽  
Renal Function Deterioration ◽  
Renal Vascular

AbstractTranscatheter arterial embolization (TAE), as an alternative to surgery for iatrogenic renal vascular injury (IRVI), may have unsatisfactory outcomes. Nonetheless, there is inadequate information regarding the predictors of TAE outcomes for IRVI in the literature. The aim of this retrospective study was to investigate the predictors of TAE outcomes for IRVI. Of 47 patients, none had major complications, 17 (36.2%) patients had minor complications, and none suffered significant renal function deterioration after TAE. Technical success and clinical success were 91.5% and 93.6%, respectively. Technical failure was associated with older age, thrombocytopenia, prolonged international normalized ratio (INR) and divisional IRVI. Clinical failure was associated with kidney failure, use of steroids, prolonged INR, and divisional IRVI. In addition, prolonged INR was a significant predictor of technical failure. This implies that aggressive measures to control the INR prior to TAE are warranted to facilitate technical success, and technical success could then be validated on post-TAE images. Furthermore, divisional IRVI was a predictor of clinical failure. Thus, divisional IRVI should undergo surgery first since TAE is prone to clinical failure. The avoidance of clinical failure is validated if divisional IRVI does not need further intervention.

scholarly journals The biliary drainage for patients with obstructive jaundice due to hepatocellular carcinoma

Kanzo ◽  
2012 ◽  
Vol 53 (11) ◽  
pp. 734-740
Author(s):  
Yoshimoto Nomura ◽  
Takashi Kagaya ◽  
Teruyuki Ueda ◽  
Hajime Sunagozaka ◽  
Hajime Takatori ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Obstructive Jaundice ◽  
Biliary Drainage

scholarly journals Role of endoscopic biliary drainage in advanced hepatocellular carcinoma with jaundice

PLoS ONE ◽  
2017 ◽  
Vol 12 (11) ◽  
pp. e0187469 ◽  
Author(s):  
Hyun Young Woo ◽  
Sung Yong Han ◽  
Jeong Heo ◽  
Dong Uk Kim ◽  
Dong Hoon Baek ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Biliary Drainage ◽  
Advanced Hepatocellular Carcinoma ◽  
Endoscopic Biliary Drainage

scholarly journals Antireflux Metal Stent for Initial Treatment of Malignant Distal Biliary Obstruction

2018 ◽  
Vol 2018 ◽  
pp. 1-8 ◽  
Author(s):  
Shinichi Morita ◽  
Yasuaki Arai ◽  
Shunsuke Sugawara ◽  
Miyuki Sone ◽  
Yasunari Sakamoto ◽  
...  
Keyword(s):  
Stent Placement ◽  
Biliary Drainage ◽  
Biliary Obstruction ◽  
Rank Test ◽  
Food Impaction ◽  
Endoscopic Biliary Drainage ◽  
Metal Stent ◽  
Technical Success ◽  
Log Rank Test ◽  
Antireflux Valve

Objectives. To compare the use of an antireflux metal stent (ARMS) with that of a conventional covered self-expandable metal stent (c-CSEMS) for initial stenting of malignant distal biliary obstruction (MDBO). Materials and Methods. We retrospectively investigated 59 consecutive patients with unresectable MDBO undergoing initial endoscopic biliary drainage. ARMS was used in 32 patients and c-CSEMS in 27. Technical success, functional success, complications, causes of recurrent biliary obstruction (RBO), time to RBO (TRBO), and reintervention were compared between the groups. Results. Stent placement was technically successful in all patients. There were no significant intergroup differences in functional success (ARMS [96.9%] versus c-CSEMS [96.2%]), complications (6.2 versus 7.4%), and RBO (48.4 versus 42.3%). Food impaction was significantly less frequent for ARMS than for c-CSEMS (P=0.037), but TRBO did not differ significantly between the groups (log-rank test, P=0.967). The median TRBO was 180.0 [interquartile range (IQR), 114.0–349.0] days for ARMS and 137.0 [IQR, 87.0–442.0] days for c-CSEMS. In both groups, reintervention for RBO was successfully completed in all patients thus treated. Conclusion. ARMS offers no advantage for initial stent placement, but food impaction is significantly prevented by the antireflux valve.

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