scholarly journals Development and evaluation of a novel fast broad-range 16S ribosomal DNA PCR and sequencing assay for diagnosis of bacterial infective endocarditis: multi-year experience in a large Canadian healthcare zone and a literature review

2016 ◽  
Vol 16 (1) ◽  
Author(s):  
Robert J. H. Miller ◽  
Barbara Chow ◽  
Dylan Pillai ◽  
Deirdre Church
2015 ◽  
Vol 53 (9) ◽  
pp. 3068-3071 ◽  
Author(s):  
Amandine Gagneux-Brunon ◽  
Florence Grattard ◽  
Jerome Morel ◽  
Florence Suy ◽  
Jean-François Fuzellier ◽  
...  

Mycoplasma spp. are rarely recognized agents of infective endocarditis. We report a case ofMycoplasma hominisprosthetic valve endocarditis diagnosed by 16S ribosomal DNA (rDNA) PCR and culture of valves in a 74-year-old man. We reviewed the literature and found only 8 other cases reported.


2020 ◽  
Vol 02 ◽  
Author(s):  
Masood Ghori ◽  
Nadya O. Al Matrooshi ◽  
Samir Al Jabbari ◽  
Ahmed Bafadel ◽  
Gopal Bhatnagar

: Infective Endocarditis (IE), a known complication of hemodialysis (HD), has recently been categorized as Healthcare-Associated Infective Endocarditis (HAIE). Single pathogen bacteremia is common, polymicrobial endocardial infection is rare in this cohort of the patients. We report a case of endocarditis caused by Enterococcus faecalis (E. faecalis) and Burkholderia cepacia (B. cepacia), a first ever reported combination of a usual and an unusual organism, respectively, in a patient on HD. Clinical presentation of the patient, its complicated course ,medical and surgical management ,along with microbial and echocardiographic findings is presented herein. The authors believe that presentation of this case of HAIE may benefit and contribute positively to cardiac science owing to the rare encounter of this organism as a pathogen in infective endocarditis and the difficulties in treating it.


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