scholarly journals Pragmatic RAndomised controlled trial of a trauma-focused guided self-help Programme versus InDividual trauma-focused cognitive Behavioural therapy for post-traumatic stress disorder (RAPID): trial protocol

2018 ◽  
Vol 18 (1) ◽  
Author(s):  
Claire Nollett ◽  
Catrin Lewis ◽  
Neil Kitchiner ◽  
Neil Roberts ◽  
Katy Addison ◽  
...  
Keyword(s):  
Post Traumatic Stress Disorder ◽  
Traumatic Stress ◽  
Controlled Trial ◽  
Behavioural Therapy ◽  
Post Traumatic Stress ◽  
Self Help ◽  
Cognitive Behavioural ◽  
Post Traumatic ◽  
Randomised Controlled ◽  
Pragmatic Randomised Controlled Trial

scholarly journals The effect of flexible cognitive–behavioural therapy and medical treatment, including antidepressants on post-traumatic stress disorder and depression in traumatised refugees: pragmatic randomised controlled clinical trial

2016 ◽  
Vol 208 (3) ◽  
pp. 252-259 ◽  
Author(s):  
Caecilie Böck Buhmann ◽  
Merete Nordentoft ◽  
Morten Ekstroem ◽  
Jessica Carlsson ◽  
Erik Lykke Mortensen
Keyword(s):  
Post Traumatic Stress Disorder ◽  
Traumatic Stress ◽  
Stress Disorder ◽  
Behavioural Therapy ◽  
Controlled Clinical Trial ◽  
Post Traumatic Stress ◽  
Cognitive Behavioural ◽  
Randomised Controlled Clinical Trial ◽  
Post Traumatic ◽  
Randomised Controlled

BackgroundLittle evidence exists on the treatment of traumatised refugees.AimsTo estimate treatment effects of flexible cognitive–behavioural therapy (CBT) and antidepressants (sertraline and mianserin) in traumatised refugees.MethodRandomised controlled clinical trial with 2×2 factorial design (registered with Clinicaltrials.gov, NCT00917397, EUDRACT no. 2008-006714-15). Participants were refugees with war-related traumatic experiences, post-traumatic stress disorder (PTSD) and without psychotic disorder. Treatment was weekly sessions with a physician and/or psychologist over 6 months.ResultsA total of 217 of 280 patients completed treatment (78%). There was no effect on PTSD symptoms, no effect of psychotherapy and no interaction between psychotherapy and medicine. A small but significant effect of treatment with antidepressants was found on depression.ConclusionsIn a pragmatic clinical setting, there was no effect of flexible CBT and antidepressants on PTSD, and there was a small-to-moderate effect of antidepressants and psychoeducation on depression in traumatised refugees.

Randomized Controlled Trial of Group Cognitive Behavioural Therapy for Post-Traumatic Stress Disorder in Children and Adolescents Exposed to Tsunami in Thailand

2014 ◽  
Vol 43 (5) ◽  
pp. 549-561 ◽  
Author(s):  
Nuttorn Pityaratstian ◽  
Vinadda Piyasil ◽  
Panom Ketumarn ◽  
Nanthawat Sitdhiraksa ◽  
Sirirat Ularntinon ◽  
...  
Keyword(s):  
Children And Adolescents ◽  
Post Traumatic Stress Disorder ◽  
Traumatic Stress ◽  
Controlled Trial ◽  
Behavioural Therapy ◽  
Post Traumatic Stress ◽  
Self Monitoring ◽  
Randomized Controlled ◽  
Cognitive Behavioural ◽  
Post Traumatic

Background: Post-traumatic stress disorder (PTSD) is a common and debilitating consequence of natural disaster in children and adolescents. Accumulating data show that cognitive behavioural therapy (CBT) is an effective treatment for PTSD. However, application of CBT in a large-scale disaster in a setting with limited resources, such as when the tsunami hit several Asian countries in 2004, poses a major problem. Aims: This randomized controlled trial aimed to test for the efficacy of the modified version of CBT for children and adolescents with PSTD. Method: Thirty-six children (aged 10–15 years) who had been diagnosed with PSTD 4 years after the tsunami were randomly allocated to either CBT or wait list. CBT was delivered in 3-day, 2-hour-daily, group format followed by 1-month posttreatment self-monitoring and daily homework. Results: Compared to the wait list, participants who received CBT demonstrated significantly greater improvement in symptoms of PTSD at 1-month follow-up, although no significant improvement was observed when the measures were done immediately posttreatment. Conclusions: Brief, group CBT is an effective treatment for PTSD in children and adolescents when delivered in conjunction with posttreatment self-monitoring and daily homework.

scholarly journals Psychological treatments for chronic post-traumatic stress disorder

2007 ◽  
Vol 190 (2) ◽  
pp. 97-104 ◽  
Author(s):  
Jonathan I. Bisson ◽  
Anke Ehlers ◽  
Rosa Matthews ◽  
Stephen Pilling ◽  
David Richards ◽  
...  
Keyword(s):  
Stress Management ◽  
Post Traumatic Stress Disorder ◽  
Traumatic Stress ◽  
Stress Disorder ◽  
Behavioural Therapy ◽  
Post Traumatic Stress ◽  
Psychological Treatments ◽  
Cognitive Behavioural ◽  
Post Traumatic ◽  
Randomised Controlled

BackgroundThe relative efficacy of different psychological treatments for chronic post-traumatic stress disorder (PTSD) is unclear.AimsTo determine the efficacy of specific psychological treatments for chronic PTSD.MethodIn a systematic review of randomised controlled trials, eligible studies were assessed against methodological qualitycriteria and data were extracted and analysed.ResultsThirty-eight randomised controlled trials were included in the meta-analysis. Trauma-focused cognitive-behavioural therapy (TFCBT), eye movement desensitisation and reprocessing (EMDR), stress management and group cognitive-behavioural therapy improved PTSD symptoms more than waiting-list or usual care. There was inconclusive evidence regarding other therapies. There was no evidence of a difference in efficacy between TFCBT and EMDR butthere was some evidence that TFCBT and EMDR were superior to stress management and other therapies, and that stress management was superior to other therapies.ConclusionsThe first-line psychological treatment for PTSD should be trauma-focused (TFCBTor EMDR).

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