scholarly journals Concomitant EGFR mutation and ALK rearrangement in multifocal lung adenocarcinoma: a case report

2020 ◽  
Vol 15 (1) ◽  
Author(s):  
Jun Fan ◽  
Junhua Wu ◽  
Bo Huang ◽  
Yili Zhu ◽  
Heshui Shi ◽  
...  
Keyword(s):  
Case Report ◽  
Lung Adenocarcinoma ◽  
Egfr Mutation ◽  
Alk Rearrangement

scholarly journals A heterochronic genetic change from an EGFR mutation to an ALK rearrangement in a patient with lung adenocarcinoma: a case report

2016 ◽  
Vol 8 (5) ◽  
pp. E345-E348 ◽  
Author(s):  
Takayuki Shiroyama ◽  
Motohiro Tamiya ◽  
Manabu Hayama ◽  
Takashi Nishihara ◽  
Takuji Nishida ◽  
...  
Keyword(s):  
Case Report ◽  
Lung Adenocarcinoma ◽  
Egfr Mutation ◽  
Genetic Change ◽  
Alk Rearrangement

scholarly journals A case of lung adenocarcinoma with a concurrent EGFR mutation and ALK rearrangement: A case report and literature review

2015 ◽  
Vol 12 (3) ◽  
pp. 4370-4375 ◽  
Author(s):  
CHUN-WEI XU ◽  
XUE-YING CAI ◽  
YUAN SHAO ◽  
YANG LI ◽  
MING-WEI SHI ◽  
...  
Keyword(s):  
Case Report ◽  
Literature Review ◽  
Lung Adenocarcinoma ◽  
Egfr Mutation ◽  
Alk Rearrangement

scholarly journals Concurrent EGFR mutation and ALK rearrangement in stage IV lung adenocarcinoma—a case report and a literature review

2021 ◽  
Vol 6 (1) ◽  
pp. e124
Author(s):  
Élia Cipriano ◽  
Helena Magalhães ◽  
Catarina Tavares ◽  
João Pinto ◽  
Luís Cirnes ◽  
...  
Keyword(s):  
Case Report ◽  
Literature Review ◽  
Lung Adenocarcinoma ◽  
Egfr Mutation ◽  
Stage Iv ◽  
Alk Rearrangement

Two different patterns of lung adenocarcinoma with concomitant EGFR mutation and ALK rearrangement

2021 ◽  
pp. 030089162110055
Author(s):  
Dashi Zhao ◽  
Jun Fan ◽  
Li Peng ◽  
Bo Huang ◽  
Yili Zhu ◽  
...  
Keyword(s):  
Lung Adenocarcinoma ◽  
Egfr Mutation ◽  
Growth Factor Receptor ◽  
Egfr Mutations ◽  
Alk Rearrangement ◽  
Molecular Alterations ◽  
Anaplastic Lymphoma ◽  
Sporadic Cases ◽  
Epidermal Growth ◽  
Rare Group

Epidermal growth factor receptor ( EGFR) mutations and anaplastic lymphoma kinase ( ALK) rearrangements are considered mutually exclusive in non-small cell lung cancer (NSCLC), especially in lung adenocarcinoma (LUAC). However, sporadic cases harboring concomitant EGFR and ALK alterations have been increasingly reported. There is no consensus opinion regarding the treatment of patients positive for both molecular alterations. NSCLC with EGFR/ ALK coalterations should be separated into two subtypes: unifocal and multifocal LUAC. Here, we present an overview of the available literature regarding this rare group of patients to provide useful suggestions for therapeutic strategies.

scholarly journals Lung Adenocarcinoma with Concurrent Exon 19 EGFR Mutation and ALK Rearrangement Responding to Erlotinib

2011 ◽  
Vol 6 (11) ◽  
pp. 1962-1963 ◽  
Author(s):  
Sanjay Popat ◽  
Alexandra Vieira de Araújo ◽  
Toon Min ◽  
John Swansbury ◽  
Melissa Dainton ◽  
...  
Keyword(s):  
Lung Adenocarcinoma ◽  
Egfr Mutation ◽  
Alk Rearrangement ◽  
Exon 19

scholarly journals Concomitant EGFR Mutation and EML4-ALK Rearrangement in Lung Adenocarcinoma Is More Frequent in Multifocal Lesions

2019 ◽  
Vol 20 (4) ◽  
pp. e517-e530 ◽  
Author(s):  
Jun Fan ◽  
Xiaofang Dai ◽  
Zhenkao Wang ◽  
Bo Huang ◽  
Heshui Shi ◽  
...  
Keyword(s):  
Lung Adenocarcinoma ◽  
Egfr Mutation ◽  
Alk Rearrangement ◽  
Multifocal Lesions

scholarly journals P3.02-043 Clinical and Genetic Features in Lung Adenocarcinoma Without EGFR Mutation and ALK Rearrangement in Taiwan

2017 ◽  
Vol 12 (11) ◽  
pp. S2252-S2253
Author(s):  
T. Shiao ◽  
C. Chiang ◽  
Y. Luo ◽  
H. Chao ◽  
H. Huang ◽  
...  
Keyword(s):  
Lung Adenocarcinoma ◽  
Egfr Mutation ◽  
Alk Rearrangement ◽  
Genetic Features

scholarly journals A Triple Rare E709K and L833V/H835L EGFR Mutation Responsive to an Irreversible Pan-HER Inhibitor: A Case Report of Lung Adenocarcinoma Treated with Afatinib

2016 ◽  
Vol 11 (5) ◽  
pp. e63-e64 ◽  
Author(s):  
Stefano Frega ◽  
PierFranco Conte ◽  
Matteo Fassan ◽  
Valentina Polo ◽  
Giulia Pasello
Keyword(s):  
Case Report ◽  
Lung Adenocarcinoma ◽  
Egfr Mutation
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