scholarly journals Erratum to: Over-expression of Toll-like receptor 2 up-regulates heme oxygenase-1 expression and decreases oxidative injury in dairy goats

Author(s):  
Shoulong Deng ◽  
Kun Yu ◽  
Wuqi Jiang ◽  
Yan Li ◽  
Sutian Wang ◽  
...  
2008 ◽  
Vol 431 (2) ◽  
pp. 123-128 ◽  
Author(s):  
Chanhee Park ◽  
Ik-Hyun Cho ◽  
Donghoon Kim ◽  
Eun-Kyeong Jo ◽  
Se-Young Choi ◽  
...  

2018 ◽  
Vol 295 ◽  
pp. 357-368 ◽  
Author(s):  
Roxana Mayra Gorojod ◽  
Agustina Alaimo ◽  
Soledad Porte Alcon ◽  
Jimena Hebe Martinez ◽  
María Eugenia Cortina ◽  
...  

Nephron ◽  
2016 ◽  
Vol 133 (4) ◽  
pp. 270-278 ◽  
Author(s):  
Vassilios Atsaves ◽  
Panagiota Makri ◽  
Maria G. Detsika ◽  
Alexandra Tsirogianni ◽  
Elias A. Lianos

2021 ◽  
Vol 8 (8) ◽  
pp. 210395
Author(s):  
Steven A. Chambers ◽  
Mathew Newman ◽  
Melissa M. Frangie ◽  
Alena V. Savenka ◽  
Alexei. G. Basnakian ◽  
...  

The discovery of chimeric anti-melanoma agents is reported. These molecules are potent growth suppressors of melanoma cells in vitro with growth inhibition of 50% (GI 50 ) values as low as 1.32 µM. Compounds were more toxic to melanoma cells in vitro than commonly used anti-melanoma agent dacarbazine as measured by TUNEL assay. They induced both caspase-independent apoptosis evident by colocalization of TUNEL with endonuclease G (EndoG) and caspase-mediated apoptosis measured by colocalization of TUNEL with caspase-activated DNase (CAD). In addition, compounds 3 and 5 strongly induced oxidative injury to melanoma cells as measured by TUNEL colocalization with heme oxygenase-1 (HO1). Dacarbazine induced only caspase-independent apoptosis, which may explain why it is less cytotoxic to melanoma cells than compounds 3 , 4 and 5 .


Sign in / Sign up

Export Citation Format

Share Document