scholarly journals The relationship between upper airway collapse and the severity of obstructive sleep apnea syndrome: a chart review

Author(s):  
Russell N. Schwartz ◽  
Richard J. Payne ◽  
Véronique-Isabelle Forest ◽  
Michael P. Hier ◽  
Amanda Fanous ◽  
...  
2011 ◽  
Vol 1 (2) ◽  
pp. 84-87
Author(s):  
M Gopinath ◽  
VV Ramachandran ◽  
Rohini Jose

ABSTRACT Obstructive sleep apnea is a chronic condition characterized by frequent episodes of upper airway collapse during sleep. Collapsibility can be increased by underlying anatomic alterations and/or disturbances in upper airway, neuromuscular control, or both, which play key roles in the pathogenesis of obstructive sleep apnea. Neurofibromas of the parapharyngeal space are the second most commonly encountered primary tumor of the nerve sheath origin. A parapharyngeal neurofibroma of the cervical sympathetic chain, presenting as obstructive sleep apnea with all the features mimicking that condition is reported here for its rarity in modern clinical practice. A transcervical approach was adopted to excise the tumor in toto, following which patient was completely relieved of the symptoms, especially those of respiratory distress and features of OSAS.


1995 ◽  
Vol 9 (3) ◽  
pp. 183-186
Author(s):  
T. Oma Hester ◽  
Howard A. Farrell ◽  
Raleigh O. Jones ◽  
Richard C. Haydon

We present two unusual cases of obstructive sleep apnea (OSA) secondary to isolated nasopharyngeal pathology. The syndrome of OSA has become more prevalent over the past two decades. Pathologic conditions that may cause OSA can occur throughout the upper airway from the nose to the larynx. In the vast majority of patients such discrete lesions are not found, but rather a combination of disproportionate anatomical relationships is found to facilitate airway collapse. Review of the literature reveals only rare cases of isolated nasopharyngeal lesions causing polysomnographically documented OSA. We present two cases of nasopharyngeal masses, a squamous cell carcinoma and a hamartoma, which presented as OSA. Although a variable amount of airway obstruction exists in most patients with nasopharyngeal masses, we report the only known case of OSA secondary to a nasopharyngeal hamartoma. Such reports underscore the importance of a thorough head and neck examination in patients presenting with OSA.


SLEEP ◽  
2009 ◽  
Vol 32 (9) ◽  
pp. 1173-1181 ◽  
Author(s):  
Jingtao Huang ◽  
Laurie R. Karamessinis ◽  
Michelle E. Pepe ◽  
Stephen M. Glinka ◽  
John M. Samuel ◽  
...  

Children ◽  
2021 ◽  
Vol 8 (11) ◽  
pp. 1032
Author(s):  
Ashley L. Saint-Fleur ◽  
Alexa Christophides ◽  
Prabhavathi Gummalla ◽  
Catherine Kier

Obstructive Sleep Apnea (OSA) is a form of sleep-disordered breathing characterized by upper airway collapse during sleep resulting in recurring arousals and desaturations. However, many aspects of this syndrome in children remain unclear. Understanding underlying pathogenic mechanisms of OSA is critical for the development of therapeutic strategies. In this article, we review current concepts surrounding the mechanism, pathogenesis, and predisposing factors of pediatric OSA. Specifically, we discuss the biomechanical properties of the upper airway that contribute to its primary role in OSA pathogenesis and examine the anatomical and neuromuscular factors that predispose to upper airway narrowing and collapsibility.


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