Assessing the magnitude of antiemetic benefit with the addition of the NK1 receptor antagonist (NK1) aprepitant for all platinum agents: Analysis of 1,872 patients (pts) in prospective randomized clinical phase III trials (RCTs).

2010 ◽  
Vol 28 (15_suppl) ◽  
pp. 9057-9057 ◽  
Author(s):  
R. J. Gralla ◽  
B. L. Rapoport ◽  
K. Jordan ◽  
J. C. Street ◽  
A. Carides
Keyword(s):  
Receptor Antagonist ◽  
Phase Iii ◽  
Nk1 Receptor ◽  
Clinical Phase ◽  
Nk1 Receptor Antagonist ◽  
Phase Iii Trials ◽  
Platinum Agents

Anxiolytic effect of NKP608, a NK1-receptor antagonist, in the social investigation test in gerbils

2002 ◽  
Vol 133 (2) ◽  
pp. 363-368 ◽  
Author(s):  
Conrad Gentsch ◽  
Margaret Cutler ◽  
Annick Vassout ◽  
Siem Veenstra ◽  
Felix Brugger
Keyword(s):  
Receptor Antagonist ◽  
Anxiolytic Effect ◽  
Nk1 Receptor ◽  
Social Investigation ◽  
The Social ◽  
Nk1 Receptor Antagonist

Anti-emetic profile of a non-peptide neurokinin NK1 receptor antagonist, CP-99,994, in ferrets

1993 ◽  
Vol 249 (1-2) ◽  
pp. R3-R4 ◽  
Author(s):  
Chaz Bountra ◽  
Keith Bunce ◽  
Timothy Dale ◽  
Christopher Gardner ◽  
Christopher Jordan ◽  
...  
Keyword(s):  
Receptor Antagonist ◽  
Nk1 Receptor ◽  
Nk1 Receptor Antagonist

scholarly journals Tachykinin NK1 receptor antagonist co-administration attenuates opioid withdrawal-mediated spinal microglia and astrocyte activation

2012 ◽  
Vol 684 (1-3) ◽  
pp. 64-70 ◽  
Author(s):  
Suneeta Tumati ◽  
Tally M. Largent-Milnes ◽  
Attila I. Keresztes ◽  
Takashi Yamamoto ◽  
Todd W. Vanderah ◽  
...  
Keyword(s):  
Receptor Antagonist ◽  
Opioid Withdrawal ◽  
Nk1 Receptor ◽  
Astrocyte Activation ◽  
Nk1 Receptor Antagonist

Potentiation of the anticonvulsant efficacy of sodium channel inhibitors by an NK1-receptor antagonist in the rat

Epilepsia ◽  
2010 ◽  
Vol 51 (8) ◽  
pp. 1543-1551 ◽  
Author(s):  
Mikhail Kalinichev ◽  
Andrea Bradford ◽  
Silvia Bison ◽  
Adam Lucas ◽  
Ilaria Sartori ◽  
...  
Keyword(s):  
Sodium Channel ◽  
Receptor Antagonist ◽  
Nk1 Receptor ◽  
Nk1 Receptor Antagonist
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