A phase 1 dose-escalation study of EC1456, a folic acid-tubulysin small-molecule drug conjugate, in adult patients (pts) with advanced solid tumors.

2014 ◽  
Vol 32 (15_suppl) ◽  
pp. TPS2630-TPS2630 ◽  
Author(s):  
Wael A. Harb ◽  
Ramesh K. Ramanathan ◽  
Daniela E. Matei ◽  
Binh Nguyen ◽  
Edward A. Sausville
Keyword(s):  
Folic Acid ◽  
Solid Tumors ◽  
Small Molecule ◽  
Dose Escalation ◽  
Phase 1 ◽  
Adult Patients ◽  
Advanced Solid Tumors ◽  
Dose Escalation Study ◽  
Drug Conjugate ◽  
Small Molecule Drug

A phase 1 dose-escalation study of BBI503, a first-in-class cancer stemness kinase inhibitor in adult patients with advanced solid tumors.

2014 ◽  
Vol 32 (15_suppl) ◽  
pp. 2527-2527 ◽  
Author(s):  
Scott Andrew Laurie ◽  
Derek J. Jonker ◽  
William Jeffery Edenfield ◽  
Joe Stephenson ◽  
Deborah Keller ◽  
...  
Keyword(s):  
Solid Tumors ◽  
Dose Escalation ◽  
Kinase Inhibitor ◽  
Phase 1 ◽  
Adult Patients ◽  
Advanced Solid Tumors ◽  
Cancer Stemness ◽  
Dose Escalation Study
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