Applications of Immunochemistry for Protein Structure Control

Purpose – This article aims to consider the use of high pressure processing in order to gain functional advantages through proteins structure control. High pressure processing has been used to produce high-quality food with extended shelf life and could also be used to modify foods functionality. Design/methodology/approach – The effect of high pressure on protein structure and functionality is looked at and comparisons are made with heat effect in places. β-lactoglobulin and whey proteins are mainly taken as examples. Findings – A controlled partial protein unfolding through mild high pressure processing could lead to a range of intermediate molecular structures. These are distinct from the native and completely unfolded structure and have been referred to as molten globules. The partly unfolded molecular states, hence, are postulated to have increased functionality and could be interesting for the food industry. Originality/value – The opportunity and challenges represented by these theoretical elements are discussed. In particular, the effect of protein concentration and aggregation is emphasised.

Download Full-text

Protein structure and interactions

Food Colloids ◽

10.1039/9781847550842-00243 ◽

2007 ◽

pp. 243-244 ◽

Cited By ~ 1

Keyword(s):

Protein Structure

Download Full-text

Solid-state NMR study of protein structure. Methods based on the measurement of internuclear distances

Journal de Chimie Physique ◽

10.1051/jcp/1995921751 ◽

1995 ◽

Vol 92 ◽

pp. 1751-1760 ◽

Cited By ~ 12

Author(s):

M Auger

Keyword(s):

Protein Structure ◽

Solid State ◽

Solid State Nmr ◽

Nmr Study ◽

Internuclear Distances

Download Full-text

Carborane–Siloxanes: Synthesis and Properties. New Possibilities for Structure Control

INEOS OPEN ◽

10.32931/io1806r ◽

2018 ◽

Vol 1 (2) ◽

pp. 71-84 ◽

Cited By ~ 10

Author(s):

A. A. Anisimov ◽

◽

A. V. Zaitsev ◽

V. A. Ol'shevskaya ◽

M. I. Buzin ◽

...

Keyword(s):

Structure Control

Download Full-text

Sequence Specific Dihedral Angle Distribution: Application in Protein Structure Prediction and Evaluation

Plant Tissue Culture and Biotechnology ◽

10.3329/ptcb.v19i2.5439 ◽

1970 ◽

Vol 19 (2) ◽

pp. 217-226

Author(s):

S. M. Minhaz Ud-Dean ◽

Mahdi Muhammad Moosa

Keyword(s):

Protein Structure ◽

Dihedral Angle ◽

Protein Structure Prediction ◽

Structure Prediction ◽

Protein Structures ◽

Angle Distribution ◽

Ramachandran Plot ◽

Specific Data ◽

Specific Distribution ◽

Structure Evaluation

Protein structure prediction and evaluation is one of the major fields of computational biology. Estimation of dihedral angle can provide information about the acceptability of both theoretically predicted and experimentally determined structures. Here we report on the sequence specific dihedral angle distribution of high resolution protein structures available in PDB and have developed Sasichandran, a tool for sequence specific dihedral angle prediction and structure evaluation. This tool will allow evaluation of a protein structure in pdb format from the sequence specific distribution of Ramachandran angles. Additionally, it will allow retrieval of the most probable Ramachandran angles for a given sequence along with the sequence specific data. Key words: Torsion angle, φ-ψ distribution, sequence specific ramachandran plot, Ramasekharan, protein structure appraisal D.O.I. 10.3329/ptcb.v19i2.5439 Plant Tissue Cult. & Biotech. 19(2): 217-226, 2009 (December)

Download Full-text