Surgical Techniques for Rat Heart and Kidney Transplantation

2019 ◽  
pp. 19-25
Author(s):  
Naoshi Kamada
Keyword(s):  
Kidney Transplantation ◽  
Rat Heart ◽  
Surgical Techniques

Kidney transplantation in rats: An appraisal of surgical techniques and outcome

Microsurgery ◽  
2003 ◽  
Vol 23 (4) ◽  
pp. 387-394 ◽  
Author(s):  
Martin Schumacher ◽  
Bruce N. Van Vliet ◽  
Paolo Ferrari
Keyword(s):  
Kidney Transplantation ◽  
Surgical Techniques

Kidney transplantation

2017 ◽  
Author(s):  
Jeff A Lafranca ◽  
Dennis A Hesselink ◽  
Frank J. M. F. Dor
Keyword(s):  
Kidney Transplantation ◽  
Therapeutic Option ◽  
Surgical Techniques ◽  
Live Donor ◽  
Live Donor Nephrectomy ◽  
Live Donor Kidney ◽  
Live Donation ◽  
Stage Renal Disease ◽  
End Stage ◽  
Surgical Aspects

Kidney transplantation is by far the best therapeutic option for most end-stage renal disease patients. However, there is an increased demand for donor organs worldwide, which cannot be met by the number of currently available organs. Live donation is the key to solving this problem, at least for kidneys. Besides the advantages of better patient and graft survival, short ischaemia times, and pre-emptive transplantation, live donor kidney transplantation offers many creative options to facilitate more transplants, such as paired kidney exchange programmes (or cross-over), unspecified and domino-paired donation. Due to new immunological possibilities, blood group AB0-incompatible transplantation and desensitization prior to transplantation are now a clinical reality. Over the years, the evolution of surgical techniques (from invasive towards minimally-invasive) for live donor nephrectomy has contributed tremendously to the success of the programme. This chapter gives a state-of-the-art overview of kidney donation and transplantation, with an emphasis on surgical aspects.

Surgical Techniques of Kidney Transplantation

2019 ◽  
pp. 157-172
Author(s):  
Christopher J.E. Watson ◽  
Peter J. Friend ◽  
Lorna P. Marson
Keyword(s):  
Kidney Transplantation ◽  
Surgical Techniques

FEATURES OF PERFORMING CADAVERIC KIDNEY TRANSPLANTATION

2021 ◽  
Vol 19 (4) ◽  
pp. 404-409
Author(s):  
А. M. Shestiuk ◽  
◽  
A. S. Karpitski ◽  
V. V. Yurkouski ◽  
◽  
...  
Keyword(s):  
Renal Failure ◽  
Kidney Transplantation ◽  
Postoperative Complications ◽  
Blood Supply ◽  
Surgical Techniques ◽  
Early Postoperative Complications ◽  
Urological Complications ◽  
Complicated Course ◽  
Cadaveric Kidney ◽  
Cadaveric Kidney Transplantation

Purpose of the study: Reducing the risk of early postoperative complications associated with the disorder of the blood supply to the donor’s ureter while carrying out the transplantation of a cadaveric kidney. Material and methods: The analysis of a complicated course of the postoperative period, associated with the peculiarities of the blood supply to the donor’s ureter, was carried out for 20 out of 410 (4.9%) patients with chronic renal failure, who had the cadaveric kidney transplanted in Brest regional clinical hospital from 2011 to 2020. Results: A technique of determining the anatomical benchmarks indicating the location of the vessels that feed the donor’s ureter has been developed. Mastering specific technical methods used during the preparation of the renal allograph and its implantation, made it possible to reduce the number of urological complications after kidney transplantation by more than 2 times, and the number of cases of postoperative necrosis of the ureter by 4 times. Conclusions: The proposed surgical techniques make it possible to reduce the risk of postoperative complications associated with the violation of the blood supply of the donor’s ureter while transplanting the cadaveric kidney.

Kidney Transplantation-Surgical Techniques

2013 ◽  
pp. 173-190
Author(s):  
Abhideep Chaudhary ◽  
Ron Shapiro ◽  
Martin Wijkstrom
Keyword(s):  
Kidney Transplantation ◽  
Surgical Techniques

scholarly journals Robot-assisted kidney transplantation. First experience

2020 ◽  
Vol 22 (2) ◽  
pp. 125-131
Author(s):  
S. V. Shchekaturov ◽  
I. V. Semeniakin ◽  
A. K. Zokoev ◽  
T. B. Makhmudov ◽  
R. R. Poghosyan
Keyword(s):  
Kidney Transplantation ◽  
Renal Disease ◽  
Kidney Transplant ◽  
End Stage Renal Disease ◽  
Graft Function ◽  
Surgical Techniques ◽  
Clinical Report ◽  
Robot Assisted ◽  
Stage Renal Disease ◽  
End Stage

Kidney transplantation is the preferred renal replacement therapy for patients with end-stage renal disease. Traditional surgical approaches consisting of vascular and urinary outflow reconstruction during kidney transplant have been sufficiently studied and standardized. However, surgical techniques are still evolving. The objective of this clinical report is to focus the attention of kidney transplant surgeons and specialists on the currently trending robot-assisted kidney transplantation (RAKT) as a minimally invasive procedure for surgical treatment of patients with end-stage renal disease. In our first experience, good primary graft function was achieved. This shows that RAKT is a surgical option. With considerable number of surgeries and experience, RAKT outcomes would be improved significantly.

scholarly journals Microsurgical techniques for experimental kidney transplantation and general guidelines to establish studies about transplantation immunology

2003 ◽  
Vol 18 (4) ◽  
pp. 355-380 ◽  
Author(s):  
Paulo Ney Aguiar Martins ◽  
Alexander Filatenkov
Keyword(s):  
Kidney Transplantation ◽  
Renal Transplantation ◽  
Organ Transplantation ◽  
Research Group ◽  
Allograft Rejection ◽  
Crucial Role ◽  
Surgical Techniques ◽  
Experimental Models ◽  
Transplantation Immunology ◽  
Microsurgical Techniques

Experimental models of organ transplantation played a crucial role to establish the principles of transplantation immunology. The renal transplantation in rodents became the most used model to study the mechanisms of allograft rejection. To perform it, it is necessary to master the microsurgery techniques and the research group should cooperate with other specialists in the field. In this article we review the surgical techniques employed in rats, and we draw guidelines to establish studies about transplantation immunology.

Development of a Vascularized Heterotopic Neonatal Rat Heart Transplantation Model

2016 ◽  
Vol 57 (3-4) ◽  
pp. 240-251
Author(s):  
Shogo Shimada ◽  
Pedro J. del Nido ◽  
Ingeborg Friehs
Keyword(s):  
Surgical Technique ◽  
Heart Transplantation ◽  
Rat Heart ◽  
Surgical Techniques ◽  
Operation Time ◽  
Neonatal Rat ◽  
Venous Anastomosis ◽  
Ischemic Time ◽  
Heterotopic Heart Transplantation ◽  
Neonatal Rat Heart

Background/Purpose: Rodent adult-to-adult heterotopic heart transplantation is a well-established animal model, and the detailed surgical technique with several modifications has been previously described. In immature donor organ transplantation, however, the surgical technique needs to be revised given the smaller size and fragility of the donor graft. Here, we report our surgical technique for heterotopic abdominal (AHTx) and femoral (FHTx) neonatal rat heart transplantation based on an experience of over 300 cases. Methods: Heterotopic heart transplantation was conducted in syngeneic Lewis rats. Neonatal rats (postnatal day 2-4) served as donors. AHTx was performed by utilizing the conventional adult-to-adult transplant method with specific modifications for optimal aortotomy and venous anastomosis. In the FHTx, the donor heart was vascularized by connecting the donor's aorta and pulmonary artery to the recipient's right femoral artery and vein, respectively, in an end-to-end manner. A specifically fashioned butterfly-shaped rubber sheet was used to align the target vessels properly. The transplanted graft was visually assessed for its viability and was accepted as a technical success when the viability met specific criteria. Successfully transplanted grafts were subject to further postoperative evaluation. Forty cases (AHTx and FHTx; n = 20 each) were compared regarding perioperative parameters and outcomes. Results: Both models were technically feasible (success rate: AHTx 75% vs. FHTx 70%) by refining the conventional heterotopic transplant technique. Injury to the fragile donor aorta and congestion of the graft due to suboptimal venous connection were predominant causes of failure, leading to refractory bleeding and poor graft viability. Although the FHTx required significantly longer operation time and graft ischemic time, the in situ graft viabilities were comparable. The FHTx provided better postoperative monitoring as it enabled daily graft palpation and better echocardiographic visualization. Conclusions: We describe detailed surgical techniques for AHTx and FHTx while addressing neonatal donor-specific issues. Following our recommendations potentially reduces the learning curve to achieve reliable and reproducible results with these challenging animal models.

scholarly journals Cadaveric kidney allograft transplantation using the Da Vinci robotic surgical system. Initial experience in the Russian Federation

2020 ◽  
Vol 22 (3) ◽  
pp. 86-98
Author(s):  
V. L. Medvedev ◽  
V. A. Porkhanov ◽  
K. E. Chernov ◽  
S. N. Volkov ◽  
G. A. Palaguta ◽  
...  
Keyword(s):  
Kidney Transplantation ◽  
Russian Federation ◽  
Da Vinci ◽  
Surgical Techniques ◽  
Open Approach ◽  
Initial Experience ◽  
The Russian Federation ◽  
Cadaveric Kidney ◽  
Robotic Surgical System ◽  
Surgical System

Kidney transplantation is the treatment of choice for patients with end-stage renal disease. In order to reduce the number of postoperative complications following open surgeries, a number of clinics in the USA and Europe are currently developing robot-assisted surgical techniques. Studies have shown that robotic surgery facilitates kidney transplantation under optimal ergonomic position for the surgeon, with functional results and patient safety comparable to those obtained under an open approach. We herein present our initial experience (in the Russian Federation) on heterotopic cadaveric kidney transplantation by laparoscopic surgery using the Da Vinci robotic surgical system.

Sign in / Sign up

Export Citation Format

Share Document