Machine learning for radiation oncology

2019 ◽  
pp. 41-59
Author(s):  
Yi Luo ◽  
Issam El Naqa
2021 ◽  
Vol 11 ◽  
Author(s):  
Stefania Volpe ◽  
Matteo Pepa ◽  
Mattia Zaffaroni ◽  
Federica Bellerba ◽  
Riccardo Santamaria ◽  
...  

Background and PurposeMachine learning (ML) is emerging as a feasible approach to optimize patients’ care path in Radiation Oncology. Applications include autosegmentation, treatment planning optimization, and prediction of oncological and toxicity outcomes. The purpose of this clinically oriented systematic review is to illustrate the potential and limitations of the most commonly used ML models in solving everyday clinical issues in head and neck cancer (HNC) radiotherapy (RT).Materials and MethodsElectronic databases were screened up to May 2021. Studies dealing with ML and radiomics were considered eligible. The quality of the included studies was rated by an adapted version of the qualitative checklist originally developed by Luo et al. All statistical analyses were performed using R version 3.6.1.ResultsForty-eight studies (21 on autosegmentation, four on treatment planning, 12 on oncological outcome prediction, 10 on toxicity prediction, and one on determinants of postoperative RT) were included in the analysis. The most common imaging modality was computed tomography (CT) (40%) followed by magnetic resonance (MR) (10%). Quantitative image features were considered in nine studies (19%). No significant differences were identified in global and methodological scores when works were stratified per their task (i.e., autosegmentation).Discussion and ConclusionThe range of possible applications of ML in the field of HN Radiation Oncology is wide, albeit this area of research is relatively young. Overall, if not safe yet, ML is most probably a bet worth making.


Healthcare ◽  
2020 ◽  
Vol 8 (3) ◽  
pp. 272
Author(s):  
Khajamoinuddin Syed ◽  
William Sleeman ◽  
Michael Hagan ◽  
Jatinder Palta ◽  
Rishabh Kapoor ◽  
...  

The Radiotherapy Incident Reporting and Analysis System (RIRAS) receives incident reports from Radiation Oncology facilities across the US Veterans Health Affairs (VHA) enterprise and Virginia Commonwealth University (VCU). In this work, we propose a computational pipeline for analysis of radiation oncology incident reports. Our pipeline uses machine learning (ML) and natural language processing (NLP) based methods to predict the severity of the incidents reported in the RIRAS platform using the textual description of the reported incidents. These incidents in RIRAS are reviewed by a radiation oncology subject matter expert (SME), who initially triages some incidents based on the salient elements in the incident report. To automate the triage process, we used the data from the VHA treatment centers and the VCU radiation oncology department. We used NLP combined with traditional ML algorithms, including support vector machine (SVM) with linear kernel, and compared it against the transfer learning approach with the universal language model fine-tuning (ULMFiT) algorithm. In RIRAS, severities are divided into four categories; A, B, C, and D, with A being the most severe to D being the least. In this work, we built models to predict High (A & B) vs. Low (C & D) severity instead of all the four categories. Models were evaluated with macro-averaged precision, recall, and F1-Score. The Traditional ML machine learning (SVM-linear) approach did well on the VHA dataset with 0.78 F1-Score but performed poorly on the VCU dataset with 0.5 F1-Score. The transfer learning approach did well on both datasets with 0.81 F1-Score on VHA dataset and 0.68 F1-Score on the VCU dataset. Overall, our methods show promise in automating the triage and severity determination process from radiotherapy incident reports.


2018 ◽  
Vol 8 ◽  
Author(s):  
Hesham Elhalawani ◽  
Timothy A. Lin ◽  
Stefania Volpe ◽  
Abdallah S. R. Mohamed ◽  
Aubrey L. White ◽  
...  

2021 ◽  
Vol 19 ◽  
pp. 13-24
Author(s):  
Matthew Field ◽  
Nicholas Hardcastle ◽  
Michael Jameson ◽  
Noel Aherne ◽  
Lois Holloway

2018 ◽  
Vol 8 ◽  
Author(s):  
Mary Feng ◽  
Gilmer Valdes ◽  
Nayha Dixit ◽  
Timothy D. Solberg

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