Mechanism-Based Competitive Binding Model to Investigate the Effect of Neonatal Fc Receptor Binding Affinity on the Pharmacokinetic of Humanized Anti-VEGF Monoclonal IgG1 Antibody in Cynomolgus Monkey

Igg1 Antibody ◽

Anti Vegf

Cynomolgus and pigtail macaque IgG subclasses: characterization of IGHG genes and computational analysis of IgG/Fc receptor binding affinity

Immunogenetics ◽

10.1007/s00251-014-0775-4 ◽

2014 ◽

Vol 66 (6) ◽

pp. 361-377 ◽

Cited By ~ 8

Author(s):

Doan C. Nguyen ◽

Rashesh Sanghvi ◽

Franco Scinicariello ◽

Joanna Pulit-Penaloza ◽

Nicole Hill ◽

...

Keyword(s):

Binding Affinity ◽

Receptor Binding ◽

Computational Analysis ◽

Fc Receptor ◽

Igg Subclasses ◽

Pigtail Macaque ◽

Hepatic Ah receptor binding affinity for 2,3,7,8-tetrachlorodibenzo-p-dioxin: similarity between beagle dog and cynomolgus monkey

Toxicology Letters ◽

10.1016/s0378-4274(99)00130-7 ◽

1999 ◽

Vol 109 (1-2) ◽

pp. 115-121 ◽

Cited By ~ 4

Author(s):

C Sandoz ◽

P Lesca ◽

J.F Narbonne

Keyword(s):

Binding Affinity ◽

Receptor Binding ◽

Cynomolgus Monkey ◽

Ah Receptor ◽

Beagle Dog ◽

Tetrachlorodibenzo P Dioxin

Modeling approach to investigate the effect of neonatal Fc receptor binding affinity and anti-therapeutic antibody on the pharmacokinetic of humanized monoclonal anti-tumor necrosis factor-α IgG antibody in cynomolgus monkey

European Journal of Pharmaceutical Sciences ◽

10.1016/j.ejps.2013.08.033 ◽

2014 ◽

Vol 51 ◽

pp. 51-58 ◽

Cited By ~ 21

Author(s):

Chee M. Ng ◽

Kelly M. Loyet ◽

Suhasini Iyer ◽

Paul J. Fielder ◽

Rong Deng

Keyword(s):

Tumor Necrosis Factor ◽

Binding Affinity ◽

Receptor Binding ◽

Cynomolgus Monkey ◽

Tumor Necrosis ◽

Tumor Necrosis Factor Α ◽

Neonatal Fc Receptor ◽

Igg Antibody ◽

Factor Α ◽

Necrosis Factor

Antiproliferative and antiviral effects of mutated IFN-alpha with increased IFN receptor binding affinity

Zeitschrift für Gastroenterologie ◽

10.1055/s-0030-1269699 ◽

2011 ◽

Vol 49 (01) ◽

Author(s):

MF Sprinzl ◽

L Bührer ◽

D Strand ◽

G Schreiber ◽

PR Galle ◽

...

Keyword(s):

Binding Affinity ◽

Receptor Binding ◽

Ifn Alpha ◽

Antiviral Effects

Ring-substituted 1,1,2,2-tetraalkylated 1,2-bis(hydroxyphenyl)ethanes. 4. Synthesis, estrogen receptor binding affinity, and evaluation of antiestrogenic and mammary tumor inhibiting activity of symmetrically disubstituted 1,1,2,2-tetramethyl-1,2-bis(hydroxyphenyl)ethanes

Journal of Medicinal Chemistry ◽

10.1021/jm00147a031 ◽

1985 ◽

Vol 28 (9) ◽

pp. 1295-1301 ◽

Cited By ~ 16

Author(s):

Rolf W. Hartmann ◽

Walter Schwarz ◽

Alexander Heindl ◽

Helmut Schoenenberger

Keyword(s):

Estrogen Receptor ◽

Binding Affinity ◽

Receptor Binding ◽

Mammary Tumor ◽

Inhibiting Activity ◽

Estrogen Receptor Binding

Correction: Mouse IgG2c Fc loop residues promote greater receptor-binding affinity than mouse IgG2b or human IgG1

PLoS ONE ◽

10.1371/journal.pone.0196609 ◽

2018 ◽

Vol 13 (4) ◽

pp. e0196609

Author(s):

Keyword(s):

Binding Affinity ◽

Receptor Binding ◽

Human Igg1

Ring-substituted 1,2-dialkylated 1,2-bis(hydroxyphenyl)ethanes. 1. Synthesis and estrogen receptor binding affinity of 2,2'- and 3,3'-disubstituted hexestrols

Journal of Medicinal Chemistry ◽

10.1021/jm00362a010 ◽

1983 ◽

Vol 26 (8) ◽

pp. 1137-1144 ◽

Cited By ~ 14

Author(s):

Rolf W. Hartmann ◽

Walter Schwarz ◽

Helmut Schoenenberger

Keyword(s):

Estrogen Receptor ◽

Binding Affinity ◽

Receptor Binding ◽

Estrogen Receptor Binding

Bromine- and Iodine-Substituted 16α,17α-Dioxolane Progestins for Breast Tumor Imaging and Radiotherapy: Synthesis and Receptor Binding Affinity

Journal of Medicinal Chemistry ◽

10.1021/jm060348q ◽

2006 ◽

Vol 49 (15) ◽

pp. 4737-4744 ◽

Cited By ~ 14

Author(s):

Dong Zhou ◽

Kathryn E. Carlson ◽

John A. Katzenellenbogen ◽

Michael J. Welch

Keyword(s):

Binding Affinity ◽

Receptor Binding ◽

Breast Tumor ◽

Tumor Imaging ◽

[Aladan3]TIPP: A fluorescent ?-opioid antagonist with high ?-receptor binding affinity and ? selectivity

Biopolymers ◽

10.1002/bip.20200 ◽

2005 ◽

Vol 80 (2-3) ◽

pp. 325-331 ◽

Cited By ~ 17

Author(s):

Heru Chen ◽

Nga N. Chung ◽

Carole Lemieux ◽

Bogumil Zelent ◽

Jane M. Vanderkooi ◽

...

Keyword(s):

Binding Affinity ◽

Receptor Binding ◽

Opioid Antagonist ◽

Additional disulfide bonds in insulin: Prediction, recombinant expression, receptor binding affinity, and stability

Protein Science ◽

10.1002/pro.2649 ◽

2015 ◽

Vol 24 (5) ◽

pp. 779-788 ◽

Cited By ~ 9

Author(s):

Tine N. Vinther ◽

Ingrid Pettersson ◽

Kasper Huus ◽

Morten Schlein ◽

Dorte B. Steensgaard ◽

...

Keyword(s):

Binding Affinity ◽

Receptor Binding ◽

Disulfide Bonds ◽

Recombinant Expression ◽