Peptide-YY and Neuropeptide-Y Inhibit Vasoactive Intestinal Peptide-Stimulated Adenosine 3′,5′-Monophosphate Production in Rat Small Intestine: Structural Requirements of Peptides for Interacting with Peptide-YY-Preferring Receptors*

Endocrinology ◽  
1989 ◽  
Vol 124 (2) ◽  
pp. 692-700 ◽  
Author(s):  
ALAIN L. SERVIN ◽  
CHRISTIANE ROUYER-FESSARD ◽  
AMBIKAIPAKAN BALASUBRAMANIAM ◽  
SERGE SAINT PIERRE ◽  
MARC LABURTHE
1990 ◽  
Vol 611 (1 Central and P) ◽  
pp. 343-346 ◽  
Author(s):  
T. VOISIN ◽  
C. ROUYER-FESSARD ◽  
M. LABURTHE

1989 ◽  
Vol 262 (2) ◽  
pp. 397-402 ◽  
Author(s):  
I Rossi ◽  
L Monge ◽  
J E Feliu

In epithelial cells isolated from rat small intestine, we have studied the influence of vasoactive intestinal peptide (VIP), a neurotransmitter which markedly increases enterocyte cyclic AMP, and of two cyclic AMP analogues (8-bromo cyclic AMP and N6,2′-O-dibutyryl cyclic AMP) on the rate of glycolysis, fructose 2,6-bisphosphate concentration and 6-phosphofructo-2-kinase activity, as well as on the rate of 3-O-methyl-D-[14C]glucose uptake. Our results show that, without affecting the rate of 3-O-methyl-D-[14C]glucose accumulation, VIP and cyclic AMP analogues were able to inhibit glucose consumption and L-lactate formation by isolated rat enterocytes. These effects occurred parallel to a significant decrease in the cellular concentration of fructose 2,6-bisphosphate and to a partial inactivation of 6-phosphofructo-2-kinase. These findings support the hypothesis that VIP inhibits glycolysis in rat enterocytes through a cyclic AMP-dependent mechanism.


1996 ◽  
Vol 116 (1) ◽  
pp. 31-37 ◽  
Author(s):  
A.M. Stadelmann ◽  
G.L. Telford ◽  
D.A. Appel ◽  
S. Walgenbach-Telford ◽  
K. Hopp ◽  
...  

2001 ◽  
Vol 120 (5) ◽  
pp. A183-A183
Author(s):  
H KOBAYASHI ◽  
H NAGATA ◽  
S MIURA ◽  
T AZUMA ◽  
H SUZUKI ◽  
...  

2001 ◽  
Vol 120 (5) ◽  
pp. A753-A754
Author(s):  
M SIMREN ◽  
G RINGSTROM ◽  
P STOTZER ◽  
H ABRAHAMSSON ◽  
E BJOMSSON

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