Heat Shock Protein 90-Dependent (Geldanamycin-Inhibited) Movement of the Glucocorticoid Receptor through the Cytoplasm to the Nucleus Requires Intact Cytoskeleton

Mario D. Galigniana; Jennifer L. Scruggs; James Herrington; Michael J. Welsh; Christin Carter-Su; Paul R. Housley; William B. Pratt

doi:10.1210/mend.12.12.0204

Heat Shock Protein 90-Dependent (Geldanamycin-Inhibited) Movement of the Glucocorticoid Receptor through the Cytoplasm to the Nucleus Requires Intact Cytoskeleton

Molecular Endocrinology ◽

10.1210/mend.12.12.0204 ◽

1998 ◽

Vol 12 (12) ◽

pp. 1903-1913 ◽

Cited By ~ 73

Author(s):

Mario D. Galigniana ◽

Jennifer L. Scruggs ◽

James Herrington ◽

Michael J. Welsh ◽

Christin Carter-Su ◽

...

Keyword(s):

Heat Shock ◽

Heat Shock Protein ◽

Glucocorticoid Receptor ◽

Heat Shock Protein 90

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Geldanamycin, an inhibitor of heat shock protein 90 (Hsp90) mediated signal transduction has anti-inflammatory effects and interacts with glucocorticoid receptor in vivo

British Journal of Pharmacology ◽

10.1038/sj.bjp.0703549 ◽

2000 ◽

Vol 131 (1) ◽

pp. 13-16 ◽

Cited By ~ 51

Author(s):

Mariarosaria Bucci ◽

Fiorentina Roviezzo ◽

Carla Cicala ◽

William C Sessa ◽

Giuseppe Cirino

Keyword(s):

Signal Transduction ◽

Heat Shock ◽

Heat Shock Protein ◽

Glucocorticoid Receptor ◽

Heat Shock Protein 90 ◽

Anti Inflammatory

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In vivo evidence for the generation of a glucocorticoid receptor-heat shock protein-90 complex incapable of binding hormone by the calmodulin antagonist phenoxybenzamine

Molecular Endocrinology ◽

10.1210/me.10.1.14 ◽

1996 ◽

Vol 10 (1) ◽

pp. 14-23 ◽

Cited By ~ 6

Author(s):

Y. M. Ning

Keyword(s):

Heat Shock ◽

Heat Shock Protein ◽

Glucocorticoid Receptor ◽

Heat Shock Protein 90 ◽

Calmodulin Antagonist

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In vivo evidence for the generation of a glucocorticoid receptor-heat shock protein-90 complex incapable of binding hormone by the calmodulin antagonist phenoxybenzamine.

Molecular Endocrinology ◽

10.1210/mend.10.1.8838141 ◽

1996 ◽

Vol 10 (1) ◽

pp. 14-23

Author(s):

Y M Ning ◽

E R Sánchez

Keyword(s):

Heat Shock ◽

Heat Shock Protein ◽

Glucocorticoid Receptor ◽

Heat Shock Protein 90 ◽

Calmodulin Antagonist

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Interaction of glucocorticoid receptor with heat shock protein 90 after chronic stress

European Neuropsychopharmacology ◽

10.1016/0924-977x(96)87809-6 ◽

1996 ◽

Vol 6 ◽

pp. 110

Author(s):

Y. Sasuga ◽

M. Asakura ◽

M. Miyamoto ◽

N. Bodaiji ◽

J. Imafuku ◽

...

Keyword(s):

Heat Shock ◽

Heat Shock Protein ◽

Glucocorticoid Receptor ◽

Chronic Stress ◽

Heat Shock Protein 90

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Optimal ligand binding by the recombinant human glucocorticoid receptor and assembly of the receptor complex with heat shock protein 90 correlate with high intracellular ATP levels in Spodoptera frugiperda cells

The Journal of Steroid Biochemistry and Molecular Biology ◽

10.1016/s0960-0760(96)00182-3 ◽

1997 ◽

Vol 60 (1-2) ◽

pp. 1-9 ◽

Cited By ~ 25

Author(s):

Ganesan Srinivasan ◽

Jan F.M. Post ◽

E.Brad Thompson

Keyword(s):

Heat Shock ◽

Heat Shock Protein ◽

Glucocorticoid Receptor ◽

Ligand Binding ◽

Spodoptera Frugiperda ◽

Heat Shock Protein 90 ◽

Receptor Complex ◽

Intracellular Atp ◽

Atp Levels

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Stable and specific binding of heat shock protein 90 by geldanamycin disrupts glucocorticoid receptor function in intact cells.

Molecular Endocrinology ◽

10.1210/mend.10.6.8776730 ◽

1996 ◽

Vol 10 (6) ◽

pp. 705-712 ◽

Cited By ~ 4

Author(s):

L Whitesell ◽

P Cook

Keyword(s):

Heat Shock ◽

Heat Shock Protein ◽

Glucocorticoid Receptor ◽

Specific Binding ◽

Heat Shock Protein 90 ◽

Receptor Function ◽

Intact Cells

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Differential Alteration of Heat Shock Protein 90 in Mice Modifies Glucocorticoid Receptor Function and Susceptibility to Trauma

Journal of Neurotrauma ◽

10.1089/neu.2009.0926 ◽

2010 ◽

Vol 27 (2) ◽

pp. 373-381 ◽

Cited By ~ 13

Author(s):

Hai-Ying Shen ◽

Yan Zhao ◽

Xing-Yun Chen ◽

Ren-Ping Xiong ◽

Jin-Li Lu ◽

...

Keyword(s):

Heat Shock ◽

Heat Shock Protein ◽

Glucocorticoid Receptor ◽

Heat Shock Protein 90 ◽

Receptor Function

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Inhibition of mineralocorticoid and glucocorticoid receptor function by the heat shock protein 90-binding agent geldanamycin1Supported by the Deutsche Forschungsgemeinschaft (DFG-Grant Ka 1039/2-1).1

Molecular and Cellular Endocrinology ◽

10.1016/s0303-7207(97)00115-9 ◽

1997 ◽

Vol 131 (2) ◽

pp. 233-240 ◽

Cited By ~ 46

Author(s):

Christoph M Bamberger ◽

Martin Wald ◽

Ana-Maria Bamberger ◽

Heinrich M Schulte

Keyword(s):

Heat Shock ◽

Heat Shock Protein ◽

Glucocorticoid Receptor ◽

Heat Shock Protein 90 ◽

Receptor Function ◽

Binding Agent ◽

Deutsche Forschungsgemeinschaft

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Heat Shock Protein 90 Is an Essential Molecular Chaperone for Nuclear Transport of Glucocorticoid Receptor β

Investigative Opthalmology & Visual Science ◽

10.1167/iovs.05-0697 ◽

2006 ◽

Vol 47 (2) ◽

pp. 700 ◽

Cited By ~ 20

Author(s):

Xinyu Zhang ◽

Abbot F. Clark ◽

Thomas Yorio

Keyword(s):

Heat Shock ◽

Heat Shock Protein ◽

Glucocorticoid Receptor ◽

Molecular Chaperone ◽

Nuclear Transport ◽

Heat Shock Protein 90

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Geldanamycin, a Heat Shock Protein 90-Binding Benzoquinone Ansamycin, Inhibits Steroid-Dependent Translocation of the Glucocorticoid Receptor from the Cytoplasm to the Nucleus†

Biochemistry ◽

10.1021/bi970648x ◽

1997 ◽

Vol 36 (25) ◽

pp. 7776-7785 ◽

Cited By ~ 99

Author(s):

Michael J. Czar ◽

Mario D. Galigniana ◽

Adam M. Silverstein ◽

William B. Pratt

Keyword(s):

Heat Shock ◽

Heat Shock Protein ◽

Glucocorticoid Receptor ◽

Heat Shock Protein 90 ◽

Steroid Dependent ◽

Benzoquinone Ansamycin

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