Congenital absence of peripheral myelin: Abnormal Schwann cell development causes lethal arthrogryposis multiplex congenita

Neurology ◽  
1988 ◽  
Vol 38 (6) ◽  
pp. 966-966 ◽  
Author(s):  
L. Charnas ◽  
B. Trapp ◽  
J. Griffin
Keyword(s):  
Schwann Cell ◽  
Cell Development ◽  
Congenital Absence ◽  
Arthrogryposis Multiplex Congenita ◽  
Schwann Cell Development

scholarly journals Genetic Events and Signaling Mechanisms Underlying Schwann Cell Fate in Development and Cancer

Neurosurgery ◽  
2020 ◽  
Author(s):  
Harish N Vasudevan ◽  
Calixto-Hope G Lucas ◽  
Javier E Villanueva-Meyer ◽  
Philip V Theodosopoulos ◽  
David R Raleigh
Keyword(s):  
Schwann Cell ◽  
Cell Fate ◽  
Cell Development ◽  
Nerve Sheath Tumor ◽  
Cell Lineages ◽  
Nerve Sheath ◽  
Signaling Mechanisms ◽  
Schwann Cell Development ◽  
Novel Therapeutic Strategies ◽  
Genetic Events

Abstract In this review, we describe Schwann cell development from embryonic neural crest cells to terminally differentiated myelinated and nonmyelinated mature Schwann cells. We focus on the genetic drivers and signaling mechanisms mediating decisions to proliferate versus differentiate during Schwann cell development, highlighting pathways that overlap with Schwann cell development and are dysregulated in tumorigenesis. We conclude by considering how our knowledge of the events underlying Schwann cell development and mouse models of schwannoma, neurofibroma, and malignant peripheral nerve sheath tumor can inform novel therapeutic strategies for patients with cancers derived from Schwann cell lineages.

scholarly journals Deficiency in the mRNA export mediator Gle1 impairs Schwann cell development in the zebrafish embryo

Neuroscience ◽  
2016 ◽  
Vol 322 ◽  
pp. 287-297 ◽  
Author(s):  
A. Seytanoglu ◽  
N.I. Alsomali ◽  
C.F. Valori ◽  
A. McGown ◽  
H.R. Kim ◽  
...  
Keyword(s):  
Schwann Cell ◽  
Zebrafish Embryo ◽  
Mrna Export ◽  
Cell Development ◽  
Schwann Cell Development

scholarly journals The tyrosine phosphatase Shp2 (PTPN11) directs Neuregulin-1/ErbB signaling throughout Schwann cell development

2009 ◽  
Vol 106 (39) ◽  
pp. 16704-16709 ◽  
Author(s):  
K. S. Grossmann ◽  
H. Wende ◽  
F. E. Paul ◽  
C. Cheret ◽  
A. N. Garratt ◽  
...  
Keyword(s):  
Schwann Cell ◽  
Tyrosine Phosphatase ◽  
Cell Development ◽  
Neuregulin 1 ◽  
Erbb Signaling ◽  
Schwann Cell Development

Schwann cell development in embryonic mouse nerves

1999 ◽  
Vol 56 (4) ◽  
pp. 334-348 ◽  
Author(s):  
Ziping Dong ◽  
Andrea Sinanan ◽  
David Parkinson ◽  
Eric Parmantier ◽  
Rhona Mirsky ◽  
...  
Keyword(s):  
Schwann Cell ◽  
Cell Development ◽  
Embryonic Mouse ◽  
Schwann Cell Development

[P35]: Role of dbpA in neural crest and Schwann cell development

2006 ◽  
Vol 24 (8) ◽  
pp. 510-510
Author(s):  
F. Castagner ◽  
S. Atanasoski ◽  
M. Balda ◽  
K. Matter ◽  
U. Suter
Keyword(s):  
Schwann Cell ◽  
Neural Crest ◽  
Cell Development ◽  
Schwann Cell Development
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