Dialogue across Borders: Angela Su’s Chimeric Antibodies

2020 ◽  
Vol 14 (4) ◽  
pp. 667-670
Author(s):  
Angela Su ◽  
Harry Yi-Jui Wu
Keyword(s):  
Chimeric Antibodies

Genetically Engineered (Chimeric) Antibodies

1989 ◽  
Vol 24 (10) ◽  
pp. 65-80 ◽  
Author(s):  
Sherie L. Morrison
Keyword(s):  
Genetically Engineered ◽  
Chimeric Antibodies

Transfectomas provide novel chimeric antibodies

Science ◽  
1985 ◽  
Vol 229 (4719) ◽  
pp. 1202-1207 ◽  
Author(s):  
S. Morrison
Keyword(s):  
Chimeric Antibodies

scholarly journals Metal-binding chimeric antibodies expressed in Escherichia coli.

1992 ◽  
Vol 89 (20) ◽  
pp. 9754-9758 ◽  
Author(s):  
J. R. Sawyer ◽  
P. W. Tucker ◽  
F. R. Blattner
Keyword(s):  
Escherichia Coli ◽  
Metal Binding ◽  
Chimeric Antibodies

scholarly journals The case of Kawasaki disease after rituximab infusion triggered by human anti-chimeric antibodies

2020 ◽  
Vol 9 (4) ◽  
pp. 392-394 ◽  
Author(s):  
Masayuki Sato ◽  
Masayoshi Yamada ◽  
Mika Nakajima ◽  
Yudai Miyama ◽  
Hirotsugu Kitayama
Keyword(s):  
Kawasaki Disease ◽  
Chimeric Antibodies

scholarly journals The immunogenicity of chimeric antibodies.

1989 ◽  
Vol 170 (6) ◽  
pp. 2153-2157 ◽  
Author(s):  
M Brüggemann ◽  
G Winter ◽  
H Waldmann ◽  
M S Neuberger
Keyword(s):  
The Self ◽  
Chimeric Antibody ◽  
Human Origin ◽  
Strong Response ◽  
Chimeric Antibodies ◽  
V Region

Mice were immunized with model xenogeneic (both the VH frameworks and the CH domains of human origin), chimeric (just VH frameworks human), or self antibodies, and the antiantibody responses were dissected. Only the self antibody did not elicit a response. A strong response was elicited by the most xenogeneic antibody with approximately 90% against the C and approximately 10% against the V. The anti-V response was not attenuated in the chimeric antibody, demonstrating that foreign VH frameworks can be sufficient to lead to a strong antiantibody response. The magnitude of this xenogeneic anti-VH response was similar to that of the allotypic response elicited by immunizing mice of the Igha allotype with an Ighb antibody. Thus, although chimerization can diminish antiantibody responses, attention should be paid both to V region immunogenicity and to polymorphism.

On the domain pairing in chimeric antibodies

2010 ◽  
Vol 47 (14) ◽  
pp. 2422-2426 ◽  
Author(s):  
Alexey Teplyakov ◽  
Galina Obmolova ◽  
Jill M. Carton ◽  
Wei Gao ◽  
Yonghong Zhao ◽  
...  
Keyword(s):  
Chimeric Antibodies ◽  
Domain Pairing

Chimeric Antibodies: Production and Applications

Methods ◽  
1995 ◽  
Vol 8 (2) ◽  
pp. 73-82 ◽  
Author(s):  
Koteswara R. Chintalacharuvu ◽  
Sherie L. Morrison
Keyword(s):  
Chimeric Antibodies

Humanization of Predicted T-Cell Epitopes Reduces the Immunogenicity of Chimeric Antibodies: New Evidence Supporting a Simple Method

2003 ◽  
Vol 22 (4) ◽  
pp. 245-257 ◽  
Author(s):  
Lourdes Roque-Navarro ◽  
Cristina Mateo ◽  
Josefa Lombardero ◽  
Geraudis Mustelier ◽  
Alicia Fernández ◽  
...  
Keyword(s):  
T Cell ◽  
T Cell Epitopes ◽  
Simple Method ◽  
Chimeric Antibodies ◽  
New Evidence
Sign in / Sign up

Export Citation Format

Share Document