Endoscopic Biopsy of Intraventricular Tumors with the Use of a Ventriculofiberscope

Abstract The results of endoscopic biopsy in 21 cases of intraventricular tumor are presented. The details of the equipment are given. Of the 21 tumors biopsied, there were 9 in the lateral ventricle, 2 in the thalamus, 6 in the anterior portion of the 3rd ventricle, and 4 in the pineal region. A correct histological diagnosis was made in 11 cases (52.4%). No serious complications were noted. The value of the procedure is discussed.

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Microsurgery of the Third Ventricle: Part 1

Neurosurgery ◽

10.1227/00006123-198103000-00006 ◽

1981 ◽

Vol 8 (3) ◽

pp. 334-356 ◽

Cited By ~ 92

Author(s):

Isao Yamamoto ◽

Albert L. Rhoton ◽

David A. Peace

Keyword(s):

Lateral Ventricle ◽

Anterior Part ◽

Third Ventricle ◽

Posterior Part ◽

Posterior Wall ◽

Pineal Region ◽

Circle Of Willis ◽

Cerebral Vein ◽

Foramen Of Monro ◽

3Rd Ventricle

Abstract The 3rd ventricle is one of the most surgically inaccessible areas in the brain. It is impossible to reach its cavity without incising some neural structures. Twenty-five cadaveric brains were examined in detail to evaluate the surgically important relationships of the walls of the 3rd ventricle. The routes through which the 3rd ventricle can be reached are: (a) from above, through the foramen of Monro and the roof after entering the lateral ventricle through the corpus callosum or the cerebral cortex; (b) from anterior, through the lamina terminalis; (c) from below, through the floor if it has been stretched by tumor; and (d) from posterior, through the pineal region or from the posterior part of the lateral ventricle through the crus of the fornix. The posterior part of the circle of Willis and the basilar artery are intimately related to the floor, the anterior part of the circle of Willis and the anterior cerebral and anterior communicating arteries are related to the anterior wall, and the posterior cerebral artery supplies the posterior wall. The deep cerebral venous system is intimately related to the 3rd ventricle; the internal cerebral vein is related to the roof, and the basal vein is related to the floor. The junction of these veins with the great vein forms a formidable obstacle to the operative approach to the pineal gland and the posterior part of the 3rd ventricle.

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Endoscopic biopsy of brain tumors in children: diagnostic success and utility in guiding treatment strategies

Journal of Neurosurgery Pediatrics ◽

10.3171/2009.10.peds09172 ◽

2010 ◽

Vol 5 (3) ◽

pp. 255-262 ◽

Cited By ~ 39

Author(s):

Edward S. Ahn ◽

Liliana Goumnerova

Keyword(s):

Brain Tumors ◽

Tumor Marker ◽

Lateral Ventricle ◽

Endoscopic Third Ventriculostomy ◽

Obstructive Hydrocephalus ◽

Pineal Region ◽

Endoscopic Biopsy ◽

Neurological Deficits ◽

Third Ventriculostomy ◽

Consecutive Series

Object Endoscopic biopsy is an important minimally invasive method of diagnosis in the initial management of lesions in children with intraventricular and periventricular tumors. The procedure can be performed in conjunction with CSF-diverting procedures for obstructive hydrocephalus. The authors present their single-institution experience in a predominantly pediatric series with respect to diagnostic efficacy, utility in guiding treatment plans, and safety. Methods A retrospective review was conducted in a consecutive series of patients who underwent endoscopic biopsy of brain tumors during a 13-year period. Results There were 33 endoscopic biopsies in 31 patients (16 males and 15 females). The average age of the patients was 11.3 years, with a mean follow-up duration of 2.4 years. The majority of biopsies were performed in conjunction with CSF-diverting procedures, such as endoscopic third ventriculostomy or fenestration of the septum pellucidum. Overall, 23 (70%) of 33 biopsies were diagnostic, with results that directed subsequent treatment. When stratified by tumor location, biopsy samples obtained in the lateral ventricle or pineal region were more favorable toward a successful diagnosis than those in the thalamus or tectal region. In 4 cases, elevated CSF tumor marker levels led to modification of the diagnosis and appropriate adjustment of treatment. The endoscopic third ventriculostomy success rate was 82.4%. There were 2 major complications (6.1%), which resulted in neurological deficits. There were no procedure-related deaths. Conclusions Endoscopic biopsy is an effective means of diagnosis of brain tumors in children. The diagnostic power may be more favorable with tumors in the lateral ventricle or pineal region. Collection of CSF during the procedure for tumor marker analysis is an integral component of diagnosis.

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Is the Real Prevalence of Pancreatic Neuroendocrine Tumors Underestimated? A Retrospective Study on a Large Series of Pancreatic Specimens

Neuroendocrinology ◽

10.1159/000499606 ◽

2019 ◽

Vol 109 (2) ◽

pp. 165-170 ◽

Cited By ~ 7

Author(s):

Stefano Partelli ◽

Fabio Giannone ◽

Marco Schiavo Lena ◽

Francesca Muffatti ◽

Valentina Andreasi ◽

...

Keyword(s):

Neuroendocrine Tumors ◽

Smoking Habit ◽

Maximum Size ◽

Histological Diagnosis ◽

Main Diagnosis ◽

Pancreatic Neuroendocrine Tumors ◽

Intraductal Papillary Mucinous Neoplasms ◽

Mucinous Neoplasms ◽

Median Diameter ◽

Made In

Background/Aims: The annual incidence of pancreatic neuroendocrine tumors (PanNET) has been estimated to be around 0.8/100,000 inhabitants. The aim of this study was to determine the frequency of incidental histological diagnosis of PanNET in pancreatic specimen evaluation for a purpose other other than PanNET diagnosis. Methods: One thousand seventy-four histopathological examinations of pancreatic specimens performed in 3 centers in Italy were retrospectively reviewed. All cases with a main pathological diagnosis of PanNET were excluded. Results: An incidental associated diagnosis of PanNET was made in 41 specimens (4%). Among those 41 cases, 29 (71%) had a largest diameter <5 mm (microadenoma), whereas the other 12 (29%) had a maximum size ≥5 mm (median diameter of the whole series = 3 mm, range 1–15). The association with a main diagnosis of intraductal papillary mucinous neoplasms (IPMN) was significantly higher for patients who had an incidental PanNET (p = 0.048). There was no association between incidental diagnosis of PanNET and age, gender, BMI, smoking habit, diabetes, and type of operation. Conclusions: The frequency of incidental histological diagnosis of PanNET is considerably high, suggesting that their real prevalence is probably underestimated. The present study suggests a possible correlation between the incidental occurrence of PanNET and IPMN.

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Endoscopic Biopsy and Third Ventriculostomy for the Management of Pineal Region Tumors

World Neurosurgery ◽

10.1016/j.wneu.2014.11.013 ◽

2015 ◽

Vol 83 (4) ◽

pp. 543-547 ◽

Cited By ~ 20

Author(s):

Aminul I. Ahmed ◽

Malik J. Zaben ◽

Nijaguna V. Mathad ◽

Owen C.E. Sparrow

Keyword(s):

Pineal Region ◽

Endoscopic Biopsy ◽

Third Ventriculostomy ◽

Pineal Region Tumors

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Tumors of the Lateral Ventricle and the Pineal Region

Neurocritical Care Management of the Neurosurgical Patient ◽

10.1016/b978-0-323-32106-8.00017-0 ◽

2018 ◽

pp. 177-185

Author(s):

Tracy S. Ma ◽

Preethi Ramchand ◽

R. Alexander Schlichter ◽

Steven Brem

Keyword(s):

Lateral Ventricle ◽

Pineal Region

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Transcallosal-lateral ventricle-choroid fissure approach for excising large pineal region tumors extending into the third ventricle: experience in 15 pediatric cases

Child s Nervous System ◽

10.1007/s00381-020-04742-z ◽

2020 ◽

Author(s):

Hu Xing ◽

Liu Jing-ping ◽

Qin Kun-ming ◽

Liao Shen-chao ◽

Tang Chun-hai ◽

...

Keyword(s):

Lateral Ventricle ◽

Third Ventricle ◽

Pineal Region ◽

Pineal Region Tumors ◽

The Third ◽

Choroid Fissure

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Congenital Obliteration of the Anterior Portion of the Lateral Ventricle

Neurology ◽

10.1212/wnl.6.7.478 ◽

1956 ◽

Vol 6 (7) ◽

pp. 478-478 ◽

Cited By ~ 4

Author(s):

F. M. Skultety ◽

R. G. Hardy

Keyword(s):

Lateral Ventricle ◽

Anterior Portion

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Underwater observations on a rare Caribbean fish, Labrisomus filamentosus (Labrisomidae) in Barbados, W.I.

Canadian Journal of Zoology ◽

10.1139/z81-225 ◽

1981 ◽

Vol 59 (8) ◽

pp. 1625-1629 ◽

Cited By ~ 1

Author(s):

Alan R. Emery ◽

Marc Labelle

Keyword(s):

Fish Habitat ◽

Anterior Portion ◽

Dorsal Fin ◽

Barrier Reefs ◽

Made In

Labrisomus filamentosus Springer, 1959 was previously known from the holotype and three specimens, and considered to be a deep-dwelling species (35–100 m). Observations were made in Barbados at much shallower depths (12–16 m) of large adults which were territorial and which used the elongate anterior portion of the dorsal fin in signalling other species of fish. Habitat was on or near sand interstices and interconnecting coral caves amongst large boulder-shaped live corals on isolated pinnacle or barrier reefs.

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