scholarly journals Shifting roles of Drosophila pair-rule gene orthologs: segmental expression and function in the milkweed bug Oncopeltus fasciatus

Development ◽  
2019 ◽  
Vol 146 (17) ◽  
pp. dev181453 ◽  
Author(s):  
Katie Reding ◽  
Mengyao Chen ◽  
Yong Lu ◽  
Alys M. Cheatle Jarvela ◽  
Leslie Pick
Keyword(s):  
Oncopeltus Fasciatus ◽  
Milkweed Bug ◽  
Pair Rule Gene ◽  
And Function ◽  
Gene Orthologs ◽  
Segmental Expression ◽  
Pair Rule

scholarly journals Shifting roles of Drosophila pair-rule gene orthologs: segmental expression and function in the milkweed bug Oncopeltus fasciatus

2019 ◽  
Author(s):  
Katie Reding ◽  
Mengyao Chen ◽  
Yong Lu ◽  
Alys M. Cheatle Jarvela ◽  
Leslie Pick
Keyword(s):  
Oncopeltus Fasciatus ◽  
Regulatory Pathways ◽  
Milkweed Bug ◽  
Regulatory Circuits ◽  
Hemimetabolous Insect ◽  
Pair Rule Gene ◽  
Summary Statement ◽  
And Function ◽  
Gene Orthologs ◽  
Pair Rule

AbstractThe discovery of pair-rule genes (PRGs) in Drosophila revealed the existence of an underlying two-segment-wide prepattern directing embryogenesis. The milkweed bug Oncopeltus, a hemimetabolous insect, is a more representative arthropod: most of its segments form sequentially after gastrulation. Here we report the expression and function of orthologs of the complete set of nine Drosophila PRGs in Oncopeltus. Seven Of-PRG-orthologs are expressed in stripes in the primordia of every segment, rather than every-other segment, Of-runt is PR-like, and several are also expressed in the segment addition zone. RNAi-mediated knockdown of Of-odd-skipped, paired and sloppy-paired impacted all segments, with no indication of PR-like register. We confirm that Of-E75A is expressed in PR-like stripes, although it is not PR in Drosophila, demonstrating the existence of an underlying PR-like prepattern in Oncopeltus. These findings reveal that a switch occurred in regulatory circuits leading to segment formation: while several holometabolous insects are “Drosophila-like,” utilizing PRG-orthologs for PR-patterning, most Of-PRGs are expressed segmentally in Oncopeltus, a more basally-branching insect. Thus, an evolutionarily stable phenotype – segment formation – is directed by alternate regulatory pathways in diverse species.Summary StatementDespite the broad of conservation of segmentation in insects, the regulatory genes underlying this process in Drosophila have different roles in the hemipteran, Oncopeltus fasciatus.

scholarly journals Conservation and variation in pair-rule gene expression and function in the intermediate-germ beetleDermestes maculatus

Development ◽  
2017 ◽  
Vol 144 (24) ◽  
pp. 4625-4636 ◽  
Author(s):  
Jie Xiang ◽  
Katie Reding ◽  
Alison Heffer ◽  
Leslie Pick
Keyword(s):  
Gene Expression ◽  
Pair Rule Gene ◽  
And Function ◽  
Pair Rule

scholarly journals Expression of pair rule gene orthologs in the blastoderm of a myriapod: evidence for pair rule-like mechanisms?

2012 ◽  
Vol 12 (1) ◽  
pp. 15 ◽  
Author(s):  
Ralf Janssen ◽  
Wim G M Damen ◽  
Graham E Budd
Keyword(s):  
Pair Rule Gene ◽  
Gene Orthologs ◽  
Pair Rule

scholarly journals The nuclear receptor E75A has a novel pair-rule-like function in patterning the milkweed bug, Oncopeltus fasciatus

2009 ◽  
Vol 334 (1) ◽  
pp. 300-310 ◽  
Author(s):  
Deniz F. Erezyilmaz ◽  
Hans C. Kelstrup ◽  
Lynn M. Riddiford
Keyword(s):  
Nuclear Receptor ◽  
Oncopeltus Fasciatus ◽  
Milkweed Bug ◽  
Pair Rule

scholarly journals Expression of myriapod pair rule gene orthologs

EvoDevo ◽  
2011 ◽  
Vol 2 (1) ◽  
pp. 5 ◽  
Author(s):  
Ralf Janssen ◽  
Graham E Budd ◽  
Nikola-Michael Prpic ◽  
Wim GM Damen
Keyword(s):  
Pair Rule Gene ◽  
Gene Orthologs ◽  
Pair Rule

Pair rule gene orthologs in spider segmentation

2005 ◽  
Vol 7 (6) ◽  
pp. 618-628 ◽  
Author(s):  
Wim G. M. Damen ◽  
Ralf Janssen ◽  
Nikola-Michael Prpic
Keyword(s):  
Pair Rule Gene ◽  
Gene Orthologs ◽  
Pair Rule
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