Wear particles from metal-on-metal total hip replacements: Effects of implant design and implantation time

Author(s):  
I Catelas ◽  
P A Campbell ◽  
J D Bobyn ◽  
J B Medley ◽  
O L Huk
Author(s):  
S Williams ◽  
J L Tipper ◽  
E Ingham ◽  
M H Stone ◽  
J Fisher

Extremely low wear rates have been reported for metal-on-metal total hip replacements, but concerns remain about the effects of metal ion release, dissolution rates and toxicity. Surface-engineered coatings have the potential to improve wear resistance and reduce the biological activity of the wear debris produced. The aim of this study was to examine the wear and wear debris generation from surface-engineered coatings: titanium nitride (TiN), chromium nitride (CrN) and chromium carbon nitride (CrCN) applied to a cobalt-chrome alloy (CoCr) substrate. The coatings were articulated against themselves in a simple geometry model. The wear particles generated were characterized and the cytotoxic effect on U937 macrophages and L929 fibroblasts assessed. The CrN and CrCN coatings showed a decrease in wear compared to the CoCr bearings and produced small (less than 40 nm in length) wear particles. The wear particles released from the surface engineered bearings also showed a decreased cytotoxic effect on cells compared to the CoCr alloy debris. The reduced wear volumes coupled with the reduced cytotoxicity per unit volume of wear indicate the potential for the clinical application of this technology.


2006 ◽  
Vol 88 (6) ◽  
pp. 1173-1182 ◽  
Author(s):  
INGRID MILOŠEV ◽  
RIHARD TREBŠE ◽  
SIMON KOVAČ ◽  
ANDREJ CÖR ◽  
VENČESLAV PIŠOT

1998 ◽  
Vol 47 (1) ◽  
pp. 151-154
Author(s):  
Koji Hiraoka ◽  
Fujio Higuchi ◽  
Rikimaru Kawabata ◽  
Akio Inoue

2011 ◽  
Vol 44 (5) ◽  
pp. 513-516 ◽  
Author(s):  
Thomas J. Joyce ◽  
Harry Grigg ◽  
David J. Langton ◽  
Antoni V.F. Nargol

2017 ◽  
Vol 27 (3) ◽  
pp. 235-240 ◽  
Author(s):  
Hafiz J. Iqbal ◽  
Waheeb A.K. Al-Azzani ◽  
Esther Jackson-Taylor ◽  
Elizabeth Clatworthy ◽  
Alun John

Purpose We aimed to assess the early outcome following revision arthroplasty for failed metal-on-metal (MoM) total hip replacements (THR) due to adverse reaction to metal debris (ARMD). Methods We reviewed 106 consecutive revision arthroplasties. Case notes and radiological investigations were reviewed to assess the complications. Oxford Hip Score (OHS) and Euroqol (EQ-5D-3L) scores were used to assess the functional outcome and improvement of quality of life. Results At a mean follow-up of 20 months (12-48 months), the mean OHS was 28.7. Pain improved in 61% patients. A majority of patients were in level 2 for all the EQ-5D-3L dimensions. The overall complication rate was 16%. Survivorship free from further revision for any cause was 94.3% at 48 months. There was no correlation between pre-revision blood metal ions and the final outcome. Conclusions Revision surgery for failed MoM hip replacement due to ARMD is associated with a relatively higher rate of complications and risk of chronic pain. There is poor correlation between serum metal ions and development of ARMD and outcome following revision surgery.


1996 ◽  
Vol 329 ◽  
pp. S206-S216 ◽  
Author(s):  
Peter F. Doorn ◽  
Patricia A. Campbell ◽  
Harlan C. Amstutz

1996 ◽  
Vol 333 ◽  
pp. 108???117 ◽  
Author(s):  
Lawrence D. Dorr ◽  
Kevin R. Hilton ◽  
Zhinian Wan ◽  
George D. Markovich ◽  
Roy Bloebaum

2003 ◽  
Vol 21 (2) ◽  
pp. 189-195 ◽  
Author(s):  
Christian Lhotka ◽  
Thomas Szekeres ◽  
Ilse Steffan ◽  
Klaus Zhuber ◽  
Karl Zweymüller

2006 ◽  
Vol 39 ◽  
pp. S530
Author(s):  
C. Brockett ◽  
S. Williams ◽  
Z. Jin ◽  
G. Isaac ◽  
J. Fisher

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