Short Chemotherapy-Free Interval Improves Oncological Outcome in Patients Undergoing Two-Stage Hepatectomy for Colorectal Liver Metastases

2016 ◽  
Vol 23 (12) ◽  
pp. 3915-3923 ◽  
Author(s):  
P. Kambakamba ◽  
M. Linecker ◽  
F. A. Alvarez ◽  
P. Samaras ◽  
C. S. Reiner ◽  
...  
Keyword(s):  
Liver Metastases ◽  
Colorectal Liver Metastases ◽  
Oncological Outcome ◽  
Two Stage ◽  
Free Interval

scholarly journals ALPPS reduces chemotherapy-free interval and may improve oncological outcome in patients with bilobar colorectal liver metastases

HPB ◽  
2016 ◽  
Vol 18 ◽  
pp. e9
Author(s):  
P. Kambakamba ◽  
M. Linecker ◽  
F.A.A. Alvarez ◽  
P. Samaras ◽  
C. Reiner ◽  
...  
Keyword(s):  
Liver Metastases ◽  
Colorectal Liver Metastases ◽  
Oncological Outcome ◽  
Free Interval

Feasibility of “Watch-and-Wait” Management before Repeat Hepatectomy for Colorectal Liver Metastases

2018 ◽  
Vol 36 (3) ◽  
pp. 233-240 ◽  
Author(s):  
Yoji Kishi ◽  
Satoshi Nara ◽  
Minoru Esaki ◽  
Kazuaki Shimada
Keyword(s):  
Liver Metastases ◽  
Colorectal Liver Metastases ◽  
Repeat Hepatectomy ◽  
Hepatic Recurrence ◽  
Free Interval ◽  
Tumor Number ◽  
Group A ◽  
Synchronous Colorectal Liver Metastases ◽  
Group B ◽  
Better Than

Background: Whether repeat hepatectomy for colorectal liver metastases should be performed after chemotherapy or observation is unclear. Methods: We selected patients with resectable hepatic recurrence after their first hepatectomies performed between 2000 and 2015. They were classified according to the further treatment: Group A, prompt repeat hepatectomy; Group B, observation; and Group C, ≤6 months of chemotherapy. In Group B/C, patients who later underwent hepatectomy and those who did not due to disease progression were classified as B1/C1 and B2/C2, respectively. Predictors of B2/C2 were evaluated. Results: Groups A, B, and C consisted of 81, 36, and 17 patients, respectively. Recurrence-free interval was longer in Group A (median months; Group A, 10.3; Group B, 5.7; Group C, 3.5; p < 0.01). Group B1/C1 and B2/C2 included 34 and 19 patients, respectively. Five-year survival after recurrence of Group B1/C1 was 56%, which was comparable with Group A (56%, p = 0.77) and better than Group B2/C2 (0%, p < 0.01). Multivariate analysis showed synchronous colorectal liver metastases (OR 7.23) and recurrent hepatic tumor number (OR 4.04) were predictors of tumor progression. Conclusion: Selecting patients optimally either for prompt or delayed repeat hepatectomy following chemotherapy or observation is a feasible strategy.

scholarly journals Comparison between two-stage hepatectomy (TSH) and tourniquet ALPPS for advanced colorectal liver metastases (CRLM)

HPB ◽  
2019 ◽  
Vol 21 ◽  
pp. S581
Author(s):  
R. Brusadin ◽  
R. Robles Campos ◽  
A. López Conesa ◽  
P.J. Gil Vázquez ◽  
V. López López ◽  
...  
Keyword(s):  
Liver Metastases ◽  
Colorectal Liver Metastases ◽  
Two Stage

scholarly journals Two-stage hepatectomy for bilateral colorectal liver metastases: a multi-institutional analysis

HPB ◽  
2018 ◽  
Vol 20 ◽  
pp. S190
Author(s):  
M.I. Chavez ◽  
C.G. Ethun ◽  
G.A. Margonis ◽  
S. Gholami ◽  
B.J. Kim ◽  
...  
Keyword(s):  
Liver Metastases ◽  
Colorectal Liver Metastases ◽  
Institutional Analysis ◽  
Two Stage

Long-Term Outcome After Conventional Two-Stage Hepatectomy Versus Tourniquet-ALPPS in Colorectal Liver Metastases: A Propensity Score Matching Analysis

2019 ◽  
Vol 43 (9) ◽  
pp. 2281-2289 ◽  
Author(s):  
Ricardo Robles-Campos ◽  
Roberto Brusadin ◽  
Asunción López-Conesa ◽  
Víctor López-López ◽  
Álvaro Navarro-Barrios ◽  
...  
Keyword(s):  
Propensity Score ◽  
Liver Metastases ◽  
Propensity Score Matching ◽  
Colorectal Liver Metastases ◽  
Two Stage ◽  
Term Outcome ◽  
Long Term Outcome ◽  
Propensity Score Matching Analysis

scholarly journals Laparoscopic left liver resections and right portal vein ligation: first step of two stage hepatectomy for colorectal liver metastases

HPB ◽  
2019 ◽  
Vol 21 ◽  
pp. S602
Author(s):  
R. Lo Tesoriere ◽  
N. Russolillo ◽  
S. Langella ◽  
F. Forchino ◽  
S. Perotti ◽  
...  
Keyword(s):  
Portal Vein ◽  
Liver Metastases ◽  
Colorectal Liver Metastases ◽  
Portal Vein Ligation ◽  
Two Stage ◽  
Left Liver ◽  
Liver Resections

Two-Stage Hepatectomy vs One-Stage Major Hepatectomy with Contralateral Resection or Ablation for Advanced Bilobar Colorectal Liver Metastases

2018 ◽  
Vol 226 (5) ◽  
pp. 825-834 ◽  
Author(s):  
Takashi Mizuno ◽  
Jordan M. Cloyd ◽  
Kiyohiko Omichi ◽  
Yun Shin Chun ◽  
Claudius Conrad ◽  
...  
Keyword(s):  
Liver Metastases ◽  
Colorectal Liver Metastases ◽  
Major Hepatectomy ◽  
Two Stage ◽  
One Stage
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