scholarly journals Catalytic Behavior of Optically Active Amino Alcohol–Borane Complex in the Enantioselective Reduction of Acetophenone OximeO-Alkyl Ethers

1987 ◽  
Vol 60 (1) ◽  
pp. 395-396 ◽  
Author(s):  
Shinichi Itsuno ◽  
Yoshiki Sakurai ◽  
Koichi Ito ◽  
Akira Hirao ◽  
Seiichi Nakahama
Keyword(s):  
Amino Alcohol ◽  
Optically Active ◽  
Catalytic Behavior ◽  
Enantioselective Reduction ◽  
Alkyl Ethers

Highly enantioselective reduction of 3-chloro-2-oxoalkanoates with fermenting bakers' yeast. A new synthesis of optically active 3-chloro-2-hydroxyalkanoates and glycidic esters

1993 ◽  
Vol 58 (2) ◽  
pp. 486-492 ◽  
Author(s):  
Sadao Tsuboi ◽  
Hiroyuki Furutani ◽  
Mohammad Hafeez Ansari ◽  
Takashi Sakai ◽  
Masanori Utaka ◽  
...  
Keyword(s):  
Optically Active ◽  
Enantioselective Reduction ◽  
New Synthesis

Preparation of secondary alcohols of high optical purity

1986 ◽  
Vol 51 (2) ◽  
pp. 401-403 ◽  
Author(s):  
Otakar Červinka ◽  
Anna Fábryová ◽  
Irina Sablukova
Keyword(s):  
Nmr Spectroscopy ◽  
Optical Purity ◽  
Optically Active ◽  
Secondary Alcohols ◽  
Lithium Aluminium Hydride ◽  
Enantioselective Reduction ◽  
H Nmr ◽  
Lithium Aluminium ◽  
High Optical Purity ◽  
Optically Pure

Partially resolved enantiomers of optically active alcohols I-V, obtained by enantioselective reduction of the corresponding ketones with lithium aluminium hydride in the presence of (-)-quinine, were converted into crystalline 3,5-dinitrobenzoates or phenylcarbamates. The esters of the nearly optically pure enantiomers were separated by crystallization from the generally more soluble esters of the racemates. Optical purity of the hydrolytically liberated alcohols was determined by 1H NMR spectroscopy in the presence of chiral shifting agents.

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