STANNOUS TRIFLATE MEDIATED ALDOL REACTION OF 3-ACYLTHIAZOLIDINE-2-THIONE: A CONVENIENT METHOD FOR THE STEREOSELECTIVE SYNTHESES OF β-HYDROXY ALDEHYDE AND β-HYDROXY CARBOXYLIC ACID DERIVATIVES

1982 ◽  
Vol 11 (12) ◽  
pp. 1903-1906 ◽  
Author(s):  
Teruaki Mukaiyama ◽  
Nobuharu Iwasawa
Keyword(s):  
Carboxylic Acid ◽  
Convenient Method ◽  
Aldol Reaction ◽  
Hydroxy Carboxylic Acid ◽  
Stereoselective Syntheses

THE APPLICATION OF THE ARNDT–EISTERT REACTION TO THE SYNTHESIS OF FATTY ACIDS OF HIGH MOLECULAR WEIGHT

1950 ◽  
Vol 28b (9) ◽  
pp. 556-560 ◽  
Author(s):  
F. A. Vandenheuvel ◽  
P. Yates
Keyword(s):  
Fatty Acids ◽  
Molecular Weight ◽  
Carboxylic Acid ◽  
Stearic Acid ◽  
High Molecular Weight ◽  
Efficient Method ◽  
Convenient Method ◽  
Ultraviolet Absorption ◽  
Aliphatic Carboxylic Acid ◽  
Eicosanoic Acid

The Arndt–Eistert reaction offers a convenient method for the synthesis of the higher members of the aliphatic carboxylic acid series. Nonadecanoic acid, eicosanoic acid, and heneicosanoic acid have been prepared successively from stearic acid in good yields. An efficient method of purification of the synthetic products is described. The ultraviolet absorption maxima for some diazoketones derived from the higher members of the aliphatic carboxylic acid series are recorded.

Simultaneous “O–Alkyl” and “O–Acyl” Lactone Cleavages from Hydroxy–Carboxylic Acid Initiators: Direct Access to Multiblock Architectures

2019 ◽  
Vol 52 (17) ◽  
pp. 6382-6392 ◽  
Author(s):  
Bryan Raeskinet ◽  
Sébastien Moins ◽  
Luke Harvey ◽  
Julien De Winter ◽  
Céline Henoumont ◽  
...  
Keyword(s):  
Carboxylic Acid ◽  
Direct Access ◽  
Hydroxy Carboxylic Acid

Discovery and characterization of GSK256073, a non-flushing hydroxy-carboxylic acid receptor 2 (HCA2) agonist

2015 ◽  
Vol 756 ◽  
pp. 1-7 ◽  
Author(s):  
Dennis Sprecher ◽  
Miles Maxwell ◽  
Joanne Goodman ◽  
Brian White ◽  
Chi-Man Tang ◽  
...  
Keyword(s):  
Carboxylic Acid ◽  
Acid Receptor ◽  
Hydroxy Carboxylic Acid
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